Interplay of physics and evolution in the likely origin of protein biochemical function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 23, 2013, Pages 9344-9349

  Skolnick, Jeffrey ^a   Gao, Mu ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Protein evolution; Protein pocket space; Protein ligand interactions

Indexed keywords

AMINO ACID; PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; MOLECULAR EVOLUTION; MOLECULAR PHYSICS; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DATA BANK; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; THERMODYNAMICS;

PROTEIN EVOLUTION; PROTEIN POCKET SPACE; PROTEIN-LIGAND INTERACTIONS;

ALGORITHMS; EVOLUTION, MOLECULAR; LIGANDS; MODELS, CHEMICAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS;

EID: 84878737382     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1300011110     Document Type: Article

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