Developmental and degenerative modulation of brain-derived neurotrophic factor transcript variants in the mouse hippocampus

International Journal of Developmental Neuroscience

Volumn 38, Issue , 2014, Pages 68-73

  Kim, Jinwook ^a   Yang, Miyoung ^b   Kim, Juhwan ^a   Song, Lina ^a   Lee, Sueun ^a   Son, Yeonghoon ^a   Kang, Sohi ^a   Bae, Chun Sik ^a   Kim, Jong Choon ^a   Kim, Sung Ho ^a   Shin, Taekyun ^c   Wang, Hongbing ^b   Moon, Changjong ^a  

^a Chonnam National University   (South Korea)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c Jeju National University   (South Korea)

Author keywords

BDNF; Exon; Hippocampus; Postnatal development; Trimethyltin

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR TRANSCRIPT VARIANT; COMPLEMENTARY DNA; RNA; TRIMETHYLTIN; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; EXON; FEMALE; HIPPOCAMPUS; MALE; MOUSE; NERVE CELL PLASTICITY; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SEIZURE; TREMOR; ANIMAL CELL; CELL DEATH; CELL DIFFERENTIATION; CELL MATURATION; CELL SURVIVAL; DENTATE GYRUS; GENE SEQUENCE; HISTOPATHOLOGY; NERVE CELL NETWORK; NERVOUS SYSTEM DEVELOPMENT; NEUROMODULATION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SYMPTOMATOLOGY;

EID: 84906717093     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2014.08.001     Document Type: Article

References (55)

1. Aid T., Kazantseva A., Piirsoo M., Palm K., Timmusk T. Mouse and rat BDNF gene structure and expression revisited. J. Neurosci. Res. 2007, 85:525-535.
2. Allen S.J., Watson J.J., Dawbarn D. The neurotrophins and their role in Alzheimer's disease. Curr. Neuropharmacol. 2011, 9:559-573.
3. Andersson H., Wetmore C., Lindqvist E., Luthman J., Olson L. Trimethyltin exposure in the rat induces delayed changes in brain-derived neurotrophic factor, fos and heat shock protein 70. Neurotoxicology 1997, 18:147-159.
4. Angelucci F., Brene S., Mathe A.A. BDNF in schizophrenia, depression and corresponding animal models. Mol. Psychiatry 2005, 10:345-352.
5. Autry A.E., Monteggia L.M. Brain-derived neurotrophic factor and neuropsychiatric disorders. Pharmacol. Rev. 2012, 64:238-258.
6. Baj G., Del Turco D., Schlaudraff J., Torelli L., Deller T., Tongiorgi E. Regulation of the spatial code for BDNF mRNA isoforms in the rat hippocampus following pilocarpine-treatment: a systematic analysis using laser microdissection and quantitative real-time PCR. Hippocampus 2013, 23:413-423.
7. Bertram E.H., Cornett J.F. The evolution of a rat model of chronic spontaneous limbic seizures. Brain Res. 1994, 661:157-162.
8. Besser R., Kramer G., Thumler R., Bohl J., Gutmann L., Hopf H.C. Acute trimethyltin limbic-cerebellar syndrome. Neurology 1987, 37:945-950.
9. Bibel M., Barde Y.A. Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev. 2000, 14:2919-2937.
10. Bramham C.R., Messaoudi E. BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog. Neurobiol. 2005, 76:99-125.
11. Chang L.W. Neuropathology of trimethyltin: a proposed pathogenetic mechanism. Fundam. Appl. Toxicol. 1986, 6:217-232.
12. Chang L.W. The neurotoxicology and pathology of organomercury, organolead, and organotin. J. Toxicol. Sci. 1990, 15(Suppl. 4):125-151.
13. Chang L.W., Tiemeyer T.M., Wenger G.R., McMillan D.E. Neuropathology of mouse hippocampus in acute trimethyltin intoxication. Neurobehav. Toxicol. Teratol. 1982, 4:149-156.
14. Chao M.V., Rajagopal R., Lee F.S. Neurotrophin signalling in health and disease. Clin. Sci. (Lond.) 2006, 110:167-173.
15. Chiaruttini C., Sonego M., Baj G., Simonato M., Tongiorgi E. BDNF mRNA splice variants display activity-dependent targeting to distinct hippocampal laminae. Mol. Cell. Neurosci. 2008, 37:11-19.
16. Corvino V., Marchese E., Giannetti S., Lattanzi W., Bonvissuto D., Biamonte F., Mongiovi A.M., Michetti F., Geloso M.C. The neuroprotective and neurogenic effects of neuropeptide Y administration in an animal model of hippocampal neurodegeneration and temporal lobe epilepsy induced by trimethyltin. J. Neurochem. 2012, 122:415-426.
17. Duman R.S., Aghajanian G.K. Synaptic dysfunction in depression: potential therapeutic targets. Science 2012, 338:68-72.
18. Friedman W.J., Olson L., Persson H. Cells that express brain-derived neurotrophic factor mRNA in the developing postnatal rat brain. Eur. J. Neurosci. 1991, 3:688-697.
19. Geloso M.C., Corvino V., Michetti F. Trimethyltin-induced hippocampal degeneration as a tool to investigate neurodegenerative processes. Neurochem. Int. 2011, 58:729-738.
20. Ginzinger D.G. Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream. Exp. Hematol. 2002, 30:503-512.
21. Hetman M., Cavanaugh J.E., Kimelman D., Xia Z. Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal. J. Neurosci. 2000, 20:2567-2574.
22. Ishida N., Akaike M., Tsutsumi S., Kanai H., Masui A., Sadamatsu M., Kuroda Y., Watanabe Y., McEwen B.S., Kato N. Trimethyltin syndrome as a hippocampal degeneration model: temporal changes and neurochemical features of seizure susceptibility and learning impairment. Neuroscience 1997, 81:1183-1191.
23. Ivanova T., Beyer C. Pre- and postnatal expression of brain-derived neurotrophic factor mRNA/protein and tyrosine protein kinase receptor B mRNA in the mouse hippocampus. Neurosci. Lett. 2001, 307:21-24.
24. Jones K.R., Farinas I., Backus C., Reichardt L.F. Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 1994, 76:989-999.
25. Kim J., Yang M., Kim S.H., Kim J.C., Wang H.B., Shin T., Moon C. Possible role of the glycogen synthase kinase-3 signaling pathway in trimethyltin-induced hippocampal neurodegeneration in mice. PLOS ONE 2013, 8:e70356.
26. Lattanzi W., Corvino V., Di Maria V., Michetti F., Geloso M.C. Gene expression profiling as a tool to investigate the molecular machinery activated during hippocampal neurodegeneration induced by trimethyltin (TMT) administration. Int. J. Mol. Sci. 2013, 14:16817-16835.
27. Liu L., Cavanaugh J.E., Wang Y., Sakagami H., Mao Z., Xia Z. ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:8532-8537.
28. Liu Q.R., Walther D., Drgon T., Polesskaya O., Lesnick T.G., Strain K.J., de Andrade M., Bower J.H., Maraganore D.M., Uhl G.R. Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's disease. Am. J. Med. Genet. B: Neuropsychiatr. Genet. 2005, 134B:93-103.
29. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001, 25:402-408.
30. Lu L.X., Yon J.H., Carter L.B., Jevtovic-Todorovic V. General anesthesia activates BDNF-dependent neuroapoptosis in the developing rat brain. Apoptosis 2006, 11:1603-1615.
31. Lubin F.D., Roth T.L., Sweatt J.D. Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J. Neurosci. 2008, 28:10576-10586.
32. Maisonpierre P.C., Belluscio L., Friedman B., Alderson R.F., Wiegand S.J., Furth M.E., Lindsay R.M., Yancopoulos G.D. NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression. Neuron 1990, 5:501-509.
33. Martinowich K., Manji H., Lu B. New insights into BDNF function in depression and anxiety. Nat. Neurosci. 2007, 10:1089-1093.
34. McAllister A.K., Katz L.C., Lo D.C. Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. Neuron 1997, 18:767-778.
35. Neves-Pereira M., Mundo E., Muglia P., King N., Macciardi F., Kennedy J.L. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am. J. Hum. Genet. 2002, 71:651-655.
36. Nguyen N., Lee S.B., Lee Y.S., Lee K.H., Ahn J.Y. Neuroprotection by NGF and BDNF against neurotoxin-exerted apoptotic death in neural stem cells are mediated through Trk receptors, activating PI3-kinase and MAPK pathways. Neurochem. Res. 2009, 34:942-951.
37. Pattabiraman P.P., Tropea D., Chiaruttini C., Tongiorgi E., Cattaneo A., Domenici L. Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo. Mol. Cell. Neurosci. 2005, 28:556-570.
38. Roceri M., Hendriks W., Racagni G., Ellenbroek B.A., Riva M.A. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Mol. Psychiatry 2002, 7:609-616.
39. Sathanoori M., Dias B.G., Nair A.R., Banerjee S.B., Tole S., Vaidya V.A. Differential regulation of multiple brain-derived neurotrophic factor transcripts in the postnatal and adult rat hippocampus during development, and in response to kainate administration. Brain Res. Mol. Brain Res. 2004, 130:170-177.
40. Schecterson L.C., Bothwell M. Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons. Neuron 1992, 9:449-463.
41. -/- mice reveals a role for neurotrophins in CNS patterning. Neuron 1997, 19:269-281.
42. Sklar P., Gabriel S.B., McInnis M.G., Bennett P., Lim Y., Tsan G., Schaffner S., Kirov G., Jones I., Owen M., Craddock N., DePaulo J.R., Lander E.S. Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor. Mol. Psychiatry 2002, 7:579-593.
43. Tandon P., Yang Y., Das K., Holmes G.L., Stafstrom C.E. Neuroprotective effects of brain-derived neurotrophic factor in seizures during development. Neuroscience 1999, 91:293-303.
44. Thoenen H. Neurotrophins and neuronal plasticity. Science 1995, 270:593-598.
45. Timmusk T., Belluardo N., Persson H., Metsis M. Developmental regulation of brain-derived neurotrophic factor messenger RNAs transcribed from different promoters in the rat brain. Neuroscience 1994, 60:287-291.
46. Timmusk T., Palm K., Metsis M., Reintam T., Paalme V., Saarma M., Persson H. Multiple promoters direct tissue-specific expression of the rat BDNF gene. Neuron 1993, 10:475-489.
47. Tyler W.J., Alonso M., Bramham C.R., Pozzo-Miller L.D. From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learn. Mem. 2002, 9:224-237.
48. Viviani B., Bartesaghi S., Corsini E., Villa P., Ghezzi P., Garau A., Galli C.L., Marinovich M. Erythropoietin protects primary hippocampal neurons increasing the expression of brain-derived neurotrophic factor. J. Neurochem. 2005, 93:412-421.
49. Wu S.Y., Wang T.F., Yu L., Jen C.J., Chuang J.I., Wu F.S., Wu C.W., Kuo Y.M. Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway. Brain Behav. Immun. 2011, 25:135-146.
50. Yakovlev A.G., Ota K., Wang G., Movsesyan V., Bao W.L., Yoshihara K., Faden A.I. Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury. J. Neurosci. 2001, 21:7439-7446.
51. Yamada K., Mizuno M., Nabeshima T. Role for brain-derived neurotrophic factor in learning and memory. Life Sci. 2002, 70:735-744.
52. Yang M., Kim J., Kim T., Kim S.H., Kim J.C., Kim J., Takayama C., Hayashi A., Joo H.G., Shin T., Moon C. Possible involvement of galectin-3 in microglial activation in the hippocampus with trimethyltin treatment. Neurochem. Int. 2012, 61:955-962.
53. Yoneyama M., Nishiyama N., Shuto M., Sugiyama C., Kawada K., Seko K., Nagashima R., Ogita K. In vivo depletion of endogenous glutathione facilitates trimethyltin-induced neuronal damage in the dentate gyrus of mice by enhancing oxidative stress. Neurochem. Int. 2008, 52:761-769.
54. Zheng F., Zhou X., Luo Y., Xiao H., Wayman G., Wang H. Regulation of brain-derived neurotrophic factor exon IV transcription through calcium responsive elements in cortical neurons. PLOS ONE 2011, 6:e28441.
55. Zheng F., Zhou X., Moon C., Wang H. Regulation of brain-derived neurotrophic factor expression in neurons. Int. J. Physiol. Pathophysiol. Pharmacol. 2012, 4:188-200.