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Volumn 39, Issue 7, 2014, Pages 1170-1178

The lateral habenula in addiction and depression: An anatomical, synaptic and behavioral overview

Author keywords

Addiction; Depression; Lateral habenula; Synapses; Synaptic plasticity

Indexed keywords

ARTICLE; AVERSION; BEHAVIOR; CELL FUNCTION; DEPRESSION; DOPAMINERGIC SYSTEM; DRUG DEPENDENCE; DRUG EXPOSURE; EPITHALAMUS; HABENULA; HUMAN; LATERAL HABENULA; MENTAL DISEASE; MESENCEPHALON; MONOAMINERGIC SYSTEM; MOOD DISORDER; MOTIVATION; NEUROANATOMY; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; REWARD; SEROTONINERGIC SYSTEM; STIMULUS; STRESS; SYNAPSE; ADDICTION; ANIMAL; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNAPTIC TRANSMISSION;

EID: 84898738049     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/ejn.12480     Document Type: Article
Times cited : (151)

References (90)
  • 3
    • 0345561552 scopus 로고    scopus 로고
    • Subnuclear organization of the rat habenular complexes
    • Andres, K.H., von During, M. & Veh, R.W. (1999) Subnuclear organization of the rat habenular complexes. J. Comp. Neurol., 407, 130-150.
    • (1999) J. Comp. Neurol. , vol.407 , pp. 130-150
    • Andres, K.H.1    von During, M.2    Veh, R.W.3
  • 4
    • 84865783996 scopus 로고    scopus 로고
    • The Role of the Habenula in Nicotine Addiction
    • 002
    • Baldwin, P.R., Alanis, R. & Salas, R. (2011) The Role of the Habenula in Nicotine Addiction. J. Addict. Res. Ther., S1(2), pii:002.
    • (2011) J. Addict. Res. Ther , vol.S1 , Issue.2 , pp. 2
    • Baldwin, P.R.1    Alanis, R.2    Salas, R.3
  • 5
    • 65649141611 scopus 로고    scopus 로고
    • The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain
    • Bianco, I.H. & Wilson, S.W. (2009) The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain. Philos. T. Roy. Soc. B., 364, 1005-1020.
    • (2009) Philos. T. Roy. Soc. B. , vol.364 , pp. 1005-1020
    • Bianco, I.H.1    Wilson, S.W.2
  • 6
    • 77955458973 scopus 로고    scopus 로고
    • Multiple timescales of memory in lateral habenula and dopamine neurons
    • Bromberg-Martin, E.S., Matsumoto, M., Nakahara, H. & Hikosaka, O. (2010) Multiple timescales of memory in lateral habenula and dopamine neurons. Neuron, 67, 499-510.
    • (2010) Neuron , vol.67 , pp. 499-510
    • Bromberg-Martin, E.S.1    Matsumoto, M.2    Nakahara, H.3    Hikosaka, O.4
  • 7
    • 84876074520 scopus 로고    scopus 로고
    • Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats
    • Brown, P.L. & Shepard, P.D. (2013) Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats. PLoS One, 8, e60678.
    • (2013) PLoS One , vol.8
    • Brown, P.L.1    Shepard, P.D.2
  • 8
    • 78650835031 scopus 로고    scopus 로고
    • Identification of brain nuclei implicated in cocaine-primed reinstatement of conditioned place preference: a behaviour dissociable from sensitization
    • Brown, R.M., Short, J.L. & Lawrence, A.J. (2010) Identification of brain nuclei implicated in cocaine-primed reinstatement of conditioned place preference: a behaviour dissociable from sensitization. PLoS One, 5, e15889.
    • (2010) PLoS One , vol.5
    • Brown, R.M.1    Short, J.L.2    Lawrence, A.J.3
  • 9
    • 0026543243 scopus 로고
    • Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit
    • Burnashev, N., Monyer, H., Seeburg, P.H. & Sakmann, B. (1992) Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit. Neuron, 8, 189-198.
    • (1992) Neuron , vol.8 , pp. 189-198
    • Burnashev, N.1    Monyer, H.2    Seeburg, P.H.3    Sakmann, B.4
  • 10
    • 1542317068 scopus 로고    scopus 로고
    • Ionic mechanism of long-lasting discharges of action potentials triggered by membrane hyperpolarization in the medial lateral habenula
    • Chang, S.Y. & Kim, U. (2004) Ionic mechanism of long-lasting discharges of action potentials triggered by membrane hyperpolarization in the medial lateral habenula. J. Neurosci., 24, 2172-2181.
    • (2004) J. Neurosci. , vol.24 , pp. 2172-2181
    • Chang, S.Y.1    Kim, U.2
  • 11
    • 0022644104 scopus 로고
    • Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat
    • Christoph, G.R., Leonzio, R.J. & Wilcox, K.S. (1986) Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat. J. Neurosci., 6, 613-619.
    • (1986) J. Neurosci. , vol.6 , pp. 613-619
    • Christoph, G.R.1    Leonzio, R.J.2    Wilcox, K.S.3
  • 13
    • 84876953664 scopus 로고    scopus 로고
    • Differential contribution of mesoaccumbens and mesohabenular dopamine to intracranial self-stimulation
    • Duchesne, V. & Boye, S.M. (2013) Differential contribution of mesoaccumbens and mesohabenular dopamine to intracranial self-stimulation. Neuropharmacology, 70, 43-50.
    • (2013) Neuropharmacology , vol.70 , pp. 43-50
    • Duchesne, V.1    Boye, S.M.2
  • 14
    • 33749556143 scopus 로고    scopus 로고
    • The role of substance P in stress and anxiety responses
    • Ebner, K. & Singewald, N. (2006) The role of substance P in stress and anxiety responses. Amino Acids, 31, 251-272.
    • (2006) Amino Acids , vol.31 , pp. 251-272
    • Ebner, K.1    Singewald, N.2
  • 15
    • 0036019879 scopus 로고    scopus 로고
    • Neural degeneration following chronic stimulant abuse reveals a weak link in brain, fasciculus retroflexus, implying the loss of forebrain control circuitry
    • Ellison, G. (2002) Neural degeneration following chronic stimulant abuse reveals a weak link in brain, fasciculus retroflexus, implying the loss of forebrain control circuitry. Eur. Neuropsychopharm., 12, 287-297.
    • (2002) Eur. Neuropsychopharm. , vol.12 , pp. 287-297
    • Ellison, G.1
  • 16
    • 57449108466 scopus 로고    scopus 로고
    • The runway model of drug self-administration
    • Ettenberg, A. (2009) The runway model of drug self-administration. Pharmacol. Biochem. Be., 91, 271-277.
    • (2009) Pharmacol. Biochem. Be. , vol.91 , pp. 271-277
    • Ettenberg, A.1
  • 17
    • 84887119512 scopus 로고    scopus 로고
    • Nicotine aversion: neurobiological mechanisms and relevance to tobacco dependence vulnerability
    • Fowler, C.D. & Kenny, P.J. (2013) Nicotine aversion: neurobiological mechanisms and relevance to tobacco dependence vulnerability. Neuropharmacology, 76(Pt B), 533-544.
    • (2013) Neuropharmacology , vol.76 , Issue.PART B , pp. 533-544
    • Fowler, C.D.1    Kenny, P.J.2
  • 21
    • 0022978868 scopus 로고
    • Time action profiles of regional cerebral glucose utilization during naloxone-precipitated morphine withdrawal
    • Geary, W.A. & Wooten, G.F. (1986) Time action profiles of regional cerebral glucose utilization during naloxone-precipitated morphine withdrawal. Brain Res. 399, 181-184.
    • (1986) Brain Res. , vol.399 , pp. 181-184
    • Geary, W.A.1    Wooten, G.F.2
  • 22
    • 0037415808 scopus 로고    scopus 로고
    • Morphologic and cytochemical criteria for the identification and delineation of individual subnuclei within the lateral habenular complex of the rat
    • Geisler, S., Andres, K.H. & Veh, R.W. (2003) Morphologic and cytochemical criteria for the identification and delineation of individual subnuclei within the lateral habenular complex of the rat. J. Comp. Neurol., 458, 78-97.
    • (2003) J. Comp. Neurol. , vol.458 , pp. 78-97
    • Geisler, S.1    Andres, K.H.2    Veh, R.W.3
  • 23
    • 84865264751 scopus 로고    scopus 로고
    • Lesions of the lateral habenula dissociate the reward-enhancing and locomotor-stimulant effects of amphetamine
    • Gifuni, A.J., Jozaghi, S., Gauthier-Lamer, A.C. & Boye, S.M. (2012) Lesions of the lateral habenula dissociate the reward-enhancing and locomotor-stimulant effects of amphetamine. Neuropharmacology, 63, 945-957.
    • (2012) Neuropharmacology , vol.63 , pp. 945-957
    • Gifuni, A.J.1    Jozaghi, S.2    Gauthier-Lamer, A.C.3    Boye, S.M.4
  • 24
    • 84883305234 scopus 로고    scopus 로고
    • Inactivation of the lateral habenula reduces anxiogenic behavior and cocaine seeking under conditions of heightened stress
    • Gill, M.J., Ghee, S.M., Harper, S.M. & See, R.E. (2013) Inactivation of the lateral habenula reduces anxiogenic behavior and cocaine seeking under conditions of heightened stress. Pharmacol. Biochem. Be., 111C, 24-29.
    • (2013) Pharmacol. Biochem. Be. , vol.111 C , pp. 24-29
    • Gill, M.J.1    Ghee, S.M.2    Harper, S.M.3    See, R.E.4
  • 25
    • 84886922650 scopus 로고    scopus 로고
    • Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms
    • Good, C.H., Wang, H., Chen, Y.H., Mejias-Aponte, C.A., Hoffman, A.F. & Lupica, C.R. (2013) Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms. J. Neurosci., 43, 16853-16864.
    • (2013) J. Neurosci. , vol.43 , pp. 16853-16864
    • Good, C.H.1    Wang, H.2    Chen, Y.H.3    Mejias-Aponte, C.A.4    Hoffman, A.F.5    Lupica, C.R.6
  • 26
    • 35448970927 scopus 로고    scopus 로고
    • Dopaminergic projections from the VTA substantially contribute to the mesohabenular pathway in the rat
    • Gruber, C., Kahl, A., Lebenheim, L., Kowski, A., Dittgen, A. & Veh, R.W. (2007) Dopaminergic projections from the VTA substantially contribute to the mesohabenular pathway in the rat. Neurosci. Lett., 427, 165-170.
    • (2007) Neurosci. Lett. , vol.427 , pp. 165-170
    • Gruber, C.1    Kahl, A.2    Lebenheim, L.3    Kowski, A.4    Dittgen, A.5    Veh, R.W.6
  • 27
    • 0030870987 scopus 로고    scopus 로고
    • Amphetamine sensitization augments amphetamine-induced Fos expression in the lateral habenula
    • Hamamura, T. & Ichimaru, Y. (1997) Amphetamine sensitization augments amphetamine-induced Fos expression in the lateral habenula. Brain Res., 767, 140-143.
    • (1997) Brain Res. , vol.767 , pp. 140-143
    • Hamamura, T.1    Ichimaru, Y.2
  • 28
    • 0017363657 scopus 로고
    • Afferent connections of the habenular nuclei in the rat. A horseradish peroxidase study, with a note on the fiber-of-passage problem
    • Herkenham, M. & Nauta, W.J. (1977) Afferent connections of the habenular nuclei in the rat. A horseradish peroxidase study, with a note on the fiber-of-passage problem. J. Comp. Neurol., 173, 123-146.
    • (1977) J. Comp. Neurol. , vol.173 , pp. 123-146
    • Herkenham, M.1    Nauta, W.J.2
  • 29
    • 0018647716 scopus 로고
    • Efferent connections of the habenular nuclei in the rat
    • Herkenham, M. & Nauta, W.J. (1979) Efferent connections of the habenular nuclei in the rat. J. Comp. Neurol., 187, 19-47.
    • (1979) J. Comp. Neurol. , vol.187 , pp. 19-47
    • Herkenham, M.1    Nauta, W.J.2
  • 30
    • 77953791927 scopus 로고    scopus 로고
    • The habenula: from stress evasion to value-based decision-making
    • Hikosaka, O. (2010) The habenula: from stress evasion to value-based decision-making. Nat. Rev. Neurosci., 11, 503-513.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 503-513
    • Hikosaka, O.1
  • 31
    • 84867762513 scopus 로고    scopus 로고
    • Ventral tegmental area glutamate neurons: electrophysiological properties and projections
    • Hnasko, T.S., Hjelmstad, G.O., Fields, H.L. & Edwards, R.H. (2012) Ventral tegmental area glutamate neurons: electrophysiological properties and projections. J. Neurosci., 32, 15076-15085.
    • (2012) J. Neurosci. , vol.32 , pp. 15076-15085
    • Hnasko, T.S.1    Hjelmstad, G.O.2    Fields, H.L.3    Edwards, R.H.4
  • 32
    • 80051565543 scopus 로고    scopus 로고
    • Negative reward signals from the lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates
    • Hong, S., Jhou, T.C., Smith, M., Saleem, K.S. & Hikosaka, O. (2011) Negative reward signals from the lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates. J. Neurosci., 31, 11457-11471.
    • (2011) J. Neurosci. , vol.31 , pp. 11457-11471
    • Hong, S.1    Jhou, T.C.2    Smith, M.3    Saleem, K.S.4    Hikosaka, O.5
  • 33
    • 83055184338 scopus 로고    scopus 로고
    • Propensity to 'relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei
    • James, M.H., Charnley, J.L., Flynn, J.R., Smith, D.W. & Dayas, C.V. (2011) Propensity to 'relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei. Neuroscience, 199, 235-242.
    • (2011) Neuroscience , vol.199 , pp. 235-242
    • James, M.H.1    Charnley, J.L.2    Flynn, J.R.3    Smith, D.W.4    Dayas, C.V.5
  • 34
    • 61549112212 scopus 로고    scopus 로고
    • The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses
    • Jhou, T.C., Fields, H.L., Baxter, M.G., Saper, C.B. & Holland, P.C. (2009) The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron, 61, 786-800.
    • (2009) Neuron , vol.61 , pp. 786-800
    • Jhou, T.C.1    Fields, H.L.2    Baxter, M.G.3    Saper, C.B.4    Holland, P.C.5
  • 35
    • 84876526512 scopus 로고    scopus 로고
    • Cocaine drives aversive conditioning via delayed activation of dopamine-responsive habenular and midbrain pathways
    • Jhou, T.C., Good, C.H., Rowley, C.S., Xu, S.P., Wang, H., Burnham, N.W., Hoffman, A.F., Lupica, C.R. & Ikemoto, S. (2013) Cocaine drives aversive conditioning via delayed activation of dopamine-responsive habenular and midbrain pathways. J. Neurosci., 33, 7501-7512.
    • (2013) J. Neurosci. , vol.33 , pp. 7501-7512
    • Jhou, T.C.1    Good, C.H.2    Rowley, C.S.3    Xu, S.P.4    Wang, H.5    Burnham, N.W.6    Hoffman, A.F.7    Lupica, C.R.8    Ikemoto, S.9
  • 36
    • 34347324115 scopus 로고    scopus 로고
    • Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism
    • Ji, H. & Shepard, P.D. (2007) Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism. J. Neurosci., 27, 6923-6930.
    • (2007) J. Neurosci. , vol.27 , pp. 6923-6930
    • Ji, H.1    Shepard, P.D.2
  • 39
    • 0032886356 scopus 로고    scopus 로고
    • Long-term alterations in benzodiazepine, muscarinic and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor density following continuous cocaine administration
    • Keys, A.S. & Ellison, G.D. (1999) Long-term alterations in benzodiazepine, muscarinic and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor density following continuous cocaine administration. Pharmacol. Toxicol., 85, 144-150.
    • (1999) Pharmacol. Toxicol. , vol.85 , pp. 144-150
    • Keys, A.S.1    Ellison, G.D.2
  • 40
    • 84881521450 scopus 로고    scopus 로고
    • A new translational target for deep brain stimulation to treat depression
    • Kiening, K. & Sartorius, A. (2013) A new translational target for deep brain stimulation to treat depression. EMBO Mol. Med., 5, 1151-1153.
    • (2013) EMBO Mol. Med. , vol.5 , pp. 1151-1153
    • Kiening, K.1    Sartorius, A.2
  • 41
    • 84860001626 scopus 로고    scopus 로고
    • Topography of descending projections from anterior insular and medial prefrontal regions to the lateral habenula of the epithalamus in the rat
    • Kim, U. & Lee, T. (2012) Topography of descending projections from anterior insular and medial prefrontal regions to the lateral habenula of the epithalamus in the rat. Eur. J. Neurosci., 35, 1253-1269.
    • (2012) Eur. J. Neurosci. , vol.35 , pp. 1253-1269
    • Kim, U.1    Lee, T.2
  • 42
    • 0035991301 scopus 로고    scopus 로고
    • Evidence for opponent-process actions of intravenous cocaine and cocaethylene
    • Knackstedt, L.A., Samimi, M.M. & Ettenberg, A. (2002) Evidence for opponent-process actions of intravenous cocaine and cocaethylene. Pharmacol. Biochem. Be., 72, 931-936.
    • (2002) Pharmacol. Biochem. Be. , vol.72 , pp. 931-936
    • Knackstedt, L.A.1    Samimi, M.M.2    Ettenberg, A.3
  • 43
    • 84884471807 scopus 로고    scopus 로고
    • Addiction is a Reward Deficit and Stress Surfeit Disorder
    • Koob, G.F. (2013) Addiction is a Reward Deficit and Stress Surfeit Disorder. Front. Psychiatry, 4, 72.
    • (2013) Front. Psychiatry , vol.4 , pp. 72
    • Koob, G.F.1
  • 44
    • 66049083193 scopus 로고    scopus 로고
    • Dopaminergic activation excites rat lateral habenular neurons in vivo
    • Kowski, A.B., Veh, R.W. & Weiss, T. (2009) Dopaminergic activation excites rat lateral habenular neurons in vivo. Neuroscience, 161, 1154-1165.
    • (2009) Neuroscience , vol.161 , pp. 1154-1165
    • Kowski, A.B.1    Veh, R.W.2    Weiss, T.3
  • 46
    • 33847684685 scopus 로고    scopus 로고
    • Anti-Hebbian long-term potentiation in the hippocampal feedback inhibitory circuit
    • Lamsa, K.P., Heeroma, J.H., Somogyi, P., Rusakov, D.A. & Kullmann, D.M. (2007) Anti-Hebbian long-term potentiation in the hippocampal feedback inhibitory circuit. Science, 315, 1262-1266.
    • (2007) Science , vol.315 , pp. 1262-1266
    • Lamsa, K.P.1    Heeroma, J.H.2    Somogyi, P.3    Rusakov, D.A.4    Kullmann, D.M.5
  • 48
    • 78651381283 scopus 로고    scopus 로고
    • Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells
    • Lecca, S., Melis, M., Luchicchi, A., Ennas, M.G., Castelli, M.P., Muntoni, A.L. & Pistis, M. (2011) Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells. Neuropsychopharmacology, 36, 589-602.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 589-602
    • Lecca, S.1    Melis, M.2    Luchicchi, A.3    Ennas, M.G.4    Castelli, M.P.5    Muntoni, A.L.6    Pistis, M.7
  • 49
    • 34247637934 scopus 로고    scopus 로고
    • A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition
    • Lecourtier, L. & Kelly, P.H. (2007) A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition. Neurosci. Biobehav. R., 5, 658-672.
    • (2007) Neurosci. Biobehav. R. , vol.5 , pp. 658-672
    • Lecourtier, L.1    Kelly, P.H.2
  • 50
    • 41549139223 scopus 로고    scopus 로고
    • Differential tonic influence of lateral habenula on prefrontal cortex and nucleus accumbens dopamine release
    • Lecourtier, L., Defrancesco, A. & Moghaddam, B. (2008) Differential tonic influence of lateral habenula on prefrontal cortex and nucleus accumbens dopamine release. Eur. J. Neurosci., 27, 1755-1762.
    • (2008) Eur. J. Neurosci. , vol.27 , pp. 1755-1762
    • Lecourtier, L.1    Defrancesco, A.2    Moghaddam, B.3
  • 51
    • 79955784136 scopus 로고    scopus 로고
    • Neurodevelopmental disruption of cortico-striatal function caused by degeneration of habenula neurons
    • Lee, Y.A. & Goto, Y. (2011) Neurodevelopmental disruption of cortico-striatal function caused by degeneration of habenula neurons. PLoS One, 6, e19450.
    • (2011) PLoS One , vol.6
    • Lee, Y.A.1    Goto, Y.2
  • 52
    • 84881648871 scopus 로고    scopus 로고
    • Habenula and ADHD: convergence on time
    • Lee, Y.A. & Goto, Y. (2013) Habenula and ADHD: convergence on time. Neurosci. Biobehav. R., 37, 1801-1809.
    • (2013) Neurosci. Biobehav. R. , vol.37 , pp. 1801-1809
    • Lee, Y.A.1    Goto, Y.2
  • 53
    • 79952129505 scopus 로고    scopus 로고
    • Synaptic potentiation onto habenula neurons in the learned helplessness model of depression
    • Li, B., Piriz, J., Mirrione, M., Chung, C., Proulx, C.D., Schulz, D., Henn, F. & Malinow, R. (2011) Synaptic potentiation onto habenula neurons in the learned helplessness model of depression. Nature, 470, 535-539.
    • (2011) Nature , vol.470 , pp. 535-539
    • Li, B.1    Piriz, J.2    Mirrione, M.3    Chung, C.4    Proulx, C.D.5    Schulz, D.6    Henn, F.7    Malinow, R.8
  • 54
    • 84883122151 scopus 로고    scopus 로고
    • betaCaMKII in lateral habenula mediates core symptoms of depression
    • Li, K., Zhou, T., Liao, L., Yang, Z., Wong, C., Henn, F., Malinow, R. & Yates, J.R.r., Hu, H. (2013) betaCaMKII in lateral habenula mediates core symptoms of depression. Science, 341, 1016-1020.
    • (2013) Science , vol.341 , pp. 1016-1020
    • Li, K.1    Zhou, T.2    Liao, L.3    Yang, Z.4    Wong, C.5    Henn, F.6    Malinow, R.7    Yates, J.H.H.8
  • 55
    • 0034707632 scopus 로고    scopus 로고
    • Differential expression of gamma-aminobutyric acid type B receptor-1a and -1b mRNA variants in GABA and non-GABAergic neurons of the rat brain
    • Liang, F., Hatanaka, Y., Saito, H., Yamamori, T. & Hashikawa, T. (2000) Differential expression of gamma-aminobutyric acid type B receptor-1a and -1b mRNA variants in GABA and non-GABAergic neurons of the rat brain. J. Comp. Neurol., 416, 475-495.
    • (2000) J. Comp. Neurol. , vol.416 , pp. 475-495
    • Liang, F.1    Hatanaka, Y.2    Saito, H.3    Yamamori, T.4    Hashikawa, T.5
  • 56
    • 0018843252 scopus 로고
    • Selective activation of the mesocortico-frontal dopaminergic neurons induced by lesion of the habenula in the rat
    • Lisoprawski, A., Herve, D., Blanc, G., Glowinski, J. & Tassin, J.P. (1980) Selective activation of the mesocortico-frontal dopaminergic neurons induced by lesion of the habenula in the rat. Brain Res., 183, 229-234.
    • (1980) Brain Res. , vol.183 , pp. 229-234
    • Lisoprawski, A.1    Herve, D.2    Blanc, G.3    Glowinski, J.4    Tassin, J.P.5
  • 57
    • 84861002229 scopus 로고    scopus 로고
    • Investigation of the neuroanatomical substrates of reward seeking following protracted abstinence in mice
    • Madsen, H.B., Brown, R.M., Short, J.L. & Lawrence, A.J. (2012) Investigation of the neuroanatomical substrates of reward seeking following protracted abstinence in mice. J. Physiol., 590, 2427-2442.
    • (2012) J. Physiol. , vol.590 , pp. 2427-2442
    • Madsen, H.B.1    Brown, R.M.2    Short, J.L.3    Lawrence, A.J.4
  • 58
    • 84866395309 scopus 로고    scopus 로고
    • Fos activation of selective afferents to ventral tegmental area during cue-induced reinstatement of cocaine seeking in rats
    • Mahler, S.V. & Aston-Jones, G.S. (2012) Fos activation of selective afferents to ventral tegmental area during cue-induced reinstatement of cocaine seeking in rats. J. Neurosci., 32, 13309-13326.
    • (2012) J. Neurosci. , vol.32 , pp. 13309-13326
    • Mahler, S.V.1    Aston-Jones, G.S.2
  • 59
    • 0021148234 scopus 로고
    • Learned helplessness and animal models of depression
    • Maier, S.F. (1984) Learned helplessness and animal models of depression. Prog. Neuropsychoph., 8, 435-446.
    • (1984) Prog. Neuropsychoph. , vol.8 , pp. 435-446
    • Maier, S.F.1
  • 61
    • 79953230027 scopus 로고    scopus 로고
    • Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area
    • Mameli, M., Bellone, C., Brown, M.T. & Luscher, C. (2011) Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area. Nat. Neurosci., 14, 414-416.
    • (2011) Nat. Neurosci. , vol.14 , pp. 414-416
    • Mameli, M.1    Bellone, C.2    Brown, M.T.3    Luscher, C.4
  • 62
    • 84865793096 scopus 로고    scopus 로고
    • Cocaine evokes projection-specific synaptic plasticity of lateral habenula neurons
    • Maroteaux, M. & Mameli, M. (2012) Cocaine evokes projection-specific synaptic plasticity of lateral habenula neurons. J. Neurosci., 32, 12641-12646.
    • (2012) J. Neurosci. , vol.32 , pp. 12641-12646
    • Maroteaux, M.1    Mameli, M.2
  • 63
    • 34347343926 scopus 로고    scopus 로고
    • Lateral habenula as a source of negative reward signals in dopamine neurons
    • Matsumoto, M. & Hikosaka, O. (2007) Lateral habenula as a source of negative reward signals in dopamine neurons. Nature, 447, 1111-1115.
    • (2007) Nature , vol.447 , pp. 1111-1115
    • Matsumoto, M.1    Hikosaka, O.2
  • 64
    • 58149127270 scopus 로고    scopus 로고
    • Representation of negative motivational value in the primate lateral habenula
    • Matsumoto, M. & Hikosaka, O. (2009) Representation of negative motivational value in the primate lateral habenula. Nat. Neurosci., 12, 77-84.
    • (2009) Nat. Neurosci. , vol.12 , pp. 77-84
    • Matsumoto, M.1    Hikosaka, O.2
  • 65
    • 80054868141 scopus 로고    scopus 로고
    • Chronic deep brain stimulation of the lateral habenula nucleus in a rat model of depression
    • Meng, H., Wang, Y., Huang, M., Lin, W., Wang, S. & Zhang, B. (2011) Chronic deep brain stimulation of the lateral habenula nucleus in a rat model of depression. Brain Res., 1422, 32-38.
    • (2011) Brain Res. , vol.1422 , pp. 32-38
    • Meng, H.1    Wang, Y.2    Huang, M.3    Lin, W.4    Wang, S.5    Zhang, B.6
  • 66
    • 0033178606 scopus 로고    scopus 로고
    • Covariation of activity in habenula and dorsal raphe nuclei following tryptophan depletion
    • Morris, J.S., Smith, K.A., Cowen, P.J., Friston, K.J. & Dolan, R.J. (1999) Covariation of activity in habenula and dorsal raphe nuclei following tryptophan depletion. NeuroImage, 10, 163-172.
    • (1999) NeuroImage , vol.10 , pp. 163-172
    • Morris, J.S.1    Smith, K.A.2    Cowen, P.J.3    Friston, K.J.4    Dolan, R.J.5
  • 67
    • 84879839639 scopus 로고    scopus 로고
    • DREADDing the lateral habenula: a review of methodological approaches for studying lateral habenula function
    • Nair, S.G., Strand, N.S. & Neumaier, J.F. (2013) DREADDing the lateral habenula: a review of methodological approaches for studying lateral habenula function. Brain Res., 1511, 93-101.
    • (2013) Brain Res. , vol.1511 , pp. 93-101
    • Nair, S.G.1    Strand, N.S.2    Neumaier, J.F.3
  • 68
    • 84875861827 scopus 로고    scopus 로고
    • A glutamatergic projection from the lateral hypothalamus targets VTA-projecting neurons in the lateral habenula of the rat
    • Poller, W.C., Madai, V.I., Bernard, R., Laube, G. & Veh, R.W. (2013) A glutamatergic projection from the lateral hypothalamus targets VTA-projecting neurons in the lateral habenula of the rat. Brain Res., 1507, 45-60.
    • (2013) Brain Res. , vol.1507 , pp. 45-60
    • Poller, W.C.1    Madai, V.I.2    Bernard, R.3    Laube, G.4    Veh, R.W.5
  • 69
    • 0024272571 scopus 로고
    • Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats
    • Porrino, L.J., Domer, F.R., Crane, A.M. & Sokoloff, L. (1988) Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats. Neuropsychopharmacology, 1, 109-118.
    • (1988) Neuropsychopharmacology , vol.1 , pp. 109-118
    • Porrino, L.J.1    Domer, F.R.2    Crane, A.M.3    Sokoloff, L.4
  • 70
    • 0035674267 scopus 로고    scopus 로고
    • Rat brain cholinergic, dopaminergic, noradrenergic and serotonergic neurons express GABAA receptors derived from the alpha3 subunit
    • Rodriguez-Pallares, J., Caruncho, H.J., Lopez-Real, A., Wojcik, S., Guerra, M.J. & Labandeira-Garcia, J.L. (2001) Rat brain cholinergic, dopaminergic, noradrenergic and serotonergic neurons express GABAA receptors derived from the alpha3 subunit. Receptor. Channel., 7, 471-478.
    • (2001) Receptor. Channel. , vol.7 , pp. 471-478
    • Rodriguez-Pallares, J.1    Caruncho, H.J.2    Lopez-Real, A.3    Wojcik, S.4    Guerra, M.J.5    Labandeira-Garcia, J.L.6
  • 71
    • 35448951377 scopus 로고    scopus 로고
    • Deep brain stimulation of the lateral habenula in treatment resistant major depression
    • Sartorius, A. & Henn, F.A. (2007) Deep brain stimulation of the lateral habenula in treatment resistant major depression. Med. Hypotheses, 69, 1305-1308.
    • (2007) Med. Hypotheses , vol.69 , pp. 1305-1308
    • Sartorius, A.1    Henn, F.A.2
  • 73
    • 84860678825 scopus 로고    scopus 로고
    • Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin
    • Shabel, S.J., Proulx, C.D., Trias, A., Murphy, R.T. & Malinow, R. (2012) Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin. Neuron, 74, 475-481.
    • (2012) Neuron , vol.74 , pp. 475-481
    • Shabel, S.J.1    Proulx, C.D.2    Trias, A.3    Murphy, R.T.4    Malinow, R.5
  • 74
    • 84859237501 scopus 로고    scopus 로고
    • Stimulation of midbrain dopaminergic structures modifies firing rates of rat lateral habenula neurons
    • Shen, X., Ruan, X. & Zhao, H. (2012) Stimulation of midbrain dopaminergic structures modifies firing rates of rat lateral habenula neurons. PLoS One, 7, e34323.
    • (2012) PLoS One , vol.7
    • Shen, X.1    Ruan, X.2    Zhao, H.3
  • 75
    • 0037435977 scopus 로고    scopus 로고
    • Opposite metabolic changes in the habenula and ventral tegmental area of a genetic model of helpless behavior
    • Shumake, J., Edwards, E. & Gonzalez-Lima, F. (2003) Opposite metabolic changes in the habenula and ventral tegmental area of a genetic model of helpless behavior. Brain Res., 963, 274-281.
    • (2003) Brain Res. , vol.963 , pp. 274-281
    • Shumake, J.1    Edwards, E.2    Gonzalez-Lima, F.3
  • 76
    • 0023266598 scopus 로고
    • Distribution of GABA-immunoreactive neurons in the thalamus of the squirrel monkey (Saimiri sciureus)
    • Smith, Y., Seguela, P. & Parent, A. (1987) Distribution of GABA-immunoreactive neurons in the thalamus of the squirrel monkey (Saimiri sciureus). Neuroscience, 22, 579-591.
    • (1987) Neuroscience , vol.22 , pp. 579-591
    • Smith, Y.1    Seguela, P.2    Parent, A.3
  • 77
    • 84864456653 scopus 로고    scopus 로고
    • Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance
    • Stamatakis, A.M. & Stuber, G.D. (2012) Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance. Nat. Neurosci., 15, 1105-1107.
    • (2012) Nat. Neurosci. , vol.15 , pp. 1105-1107
    • Stamatakis, A.M.1    Stuber, G.D.2
  • 79
    • 84893747641 scopus 로고    scopus 로고
    • What's better for me? Fundamental role for lateral habenula in promoting subjective decision biases
    • Stopper, C.M. & Floresco, S.B. (2014) What's better for me? Fundamental role for lateral habenula in promoting subjective decision biases. Nat. Neurosci., 17, 33-35.
    • (2014) Nat. Neurosci. , vol.17 , pp. 33-35
    • Stopper, C.M.1    Floresco, S.B.2
  • 80
    • 84883766007 scopus 로고    scopus 로고
    • Mechanisms of dopamine transporter regulation in normal and disease states
    • Vaughan, R.A. & Foster, J.D. (2013) Mechanisms of dopamine transporter regulation in normal and disease states. Trends Pharmacol. Sci., 34, 489-496.
    • (2013) Trends Pharmacol. Sci. , vol.34 , pp. 489-496
    • Vaughan, R.A.1    Foster, J.D.2
  • 81
    • 0017744244 scopus 로고
    • Physiological evidence for habenula as major link between forebrain and midbrain raphe
    • Wang, R.Y. & Aghajanian, G.K. (1977) Physiological evidence for habenula as major link between forebrain and midbrain raphe. Science, 197, 89-91.
    • (1977) Science , vol.197 , pp. 89-91
    • Wang, R.Y.1    Aghajanian, G.K.2
  • 82
    • 33749066568 scopus 로고    scopus 로고
    • Absence of GABA type A signaling in adult medial habenular neurons
    • Wang, D.G., Gong, N., Luo, B. & Xu, T.L. (2006) Absence of GABA type A signaling in adult medial habenular neurons. Neuroscience, 141, 133-141.
    • (2006) Neuroscience , vol.141 , pp. 133-141
    • Wang, D.G.1    Gong, N.2    Luo, B.3    Xu, T.L.4
  • 83
    • 78650733049 scopus 로고    scopus 로고
    • Morphological and electrophysiological characteristics of neurons within identified subnuclei of the lateral habenula in rat brain slices
    • Weiss, T. & Veh, R.W. (2011) Morphological and electrophysiological characteristics of neurons within identified subnuclei of the lateral habenula in rat brain slices. Neuroscience, 172, 74-93.
    • (2011) Neuroscience , vol.172 , pp. 74-93
    • Weiss, T.1    Veh, R.W.2
  • 84
    • 78149414084 scopus 로고    scopus 로고
    • Pharmacological inhibition of the lateral habenula improves depressive-like behavior in an animal model of treatment resistant depression
    • Winter, C., Vollmayr, B., Djodari-Irani, A., Klein, J. & Sartorius, A. (2011) Pharmacological inhibition of the lateral habenula improves depressive-like behavior in an animal model of treatment resistant depression. Behav. Brain Res., 216, 463-465.
    • (2011) Behav. Brain Res. , vol.216 , pp. 463-465
    • Winter, C.1    Vollmayr, B.2    Djodari-Irani, A.3    Klein, J.4    Sartorius, A.5
  • 85
    • 38749114701 scopus 로고    scopus 로고
    • Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus
    • Yang, L.M., Hu, B., Xia, Y.H., Zhang, B.L. & Zhao, H. (2008) Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus. Behav. Brain Res., 188, 84-90.
    • (2008) Behav. Brain Res. , vol.188 , pp. 84-90
    • Yang, L.M.1    Hu, B.2    Xia, Y.H.3    Zhang, B.L.4    Zhao, H.5
  • 86
    • 84889594115 scopus 로고    scopus 로고
    • Substance P receptor antagonist in lateral habenula improves rat depression-like behaviors
    • Yang, L.M., Yu, L., Jin, H.J. & Zhao, H. (2014) Substance P receptor antagonist in lateral habenula improves rat depression-like behaviors. Brain Res. Bull., 100, 22-28.
    • (2014) Brain Res. Bull. , vol.100 , pp. 22-28
    • Yang, L.M.1    Yu, L.2    Jin, H.J.3    Zhao, H.4
  • 87
    • 84858006374 scopus 로고    scopus 로고
    • Amphetamine differentially modifies the expression of monoaminergic and GABAergic synaptic boutons and processes in lateral habenula, dorsal and ventral hippocampal formation
    • Yin, H.S., Tien, T.W., Li, L., Yang, Y.H. & Lai, C.C. (2012) Amphetamine differentially modifies the expression of monoaminergic and GABAergic synaptic boutons and processes in lateral habenula, dorsal and ventral hippocampal formation. Neurotoxicology, 33, 235-245.
    • (2012) Neurotoxicology , vol.33 , pp. 235-245
    • Yin, H.S.1    Tien, T.W.2    Li, L.3    Yang, Y.H.4    Lai, C.C.5
  • 88
    • 23044452474 scopus 로고    scopus 로고
    • Increased c-Fos expression in the medial part of the lateral habenula during cue-evoked heroin-seeking in rats
    • Zhang, F., Zhou, W., Liu, H., Zhu, H., Tang, S., Lai, M. & Yang, G. (2005) Increased c-Fos expression in the medial part of the lateral habenula during cue-evoked heroin-seeking in rats. Neurosci. Lett., 386, 133-137.
    • (2005) Neurosci. Lett. , vol.386 , pp. 133-137
    • Zhang, F.1    Zhou, W.2    Liu, H.3    Zhu, H.4    Tang, S.5    Lai, M.6    Yang, G.7
  • 89
    • 84885078829 scopus 로고    scopus 로고
    • The lateral habenula is a common target of cocaine and dexamethasone
    • Zhang, C.X., Zhang, H., Xu, H.Y., Li, M.X. & Wang, S. (2013) The lateral habenula is a common target of cocaine and dexamethasone. Neurosci. Lett., 555, 12-17.
    • (2013) Neurosci. Lett. , vol.555 , pp. 12-17
    • Zhang, C.X.1    Zhang, H.2    Xu, H.Y.3    Li, M.X.4    Wang, S.5
  • 90
    • 84876985063 scopus 로고    scopus 로고
    • Cocaine facilitates glutamatergic transmission and activates lateral habenular neurons
    • Zuo, W., Chen, L., Wang, L. & Ye, J.H. (2013) Cocaine facilitates glutamatergic transmission and activates lateral habenular neurons. Neuropharmacology, 70, 180-189.
    • (2013) Neuropharmacology , vol.70 , pp. 180-189
    • Zuo, W.1    Chen, L.2    Wang, L.3    Ye, J.H.4


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