Widespread grey matter pathology dominates the longitudinal cerebral MRI and clinical landscape of amyotrophic lateral sclerosis

Brain

Volumn 137, Issue 9, 2014, Pages 2546-2555

  Menke, Ricarda A L ^a,b   Körner, Sonja ^c   Filippini, Nicola ^a   Douaud, Gwenaëlle ^a,b   Knight, Steven ^a   Talbot, Kevin ^b   Turner, Martin R ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Biomarker; Diffusion tensor imaging; Magnetic resonance imaging; Motor neuron disease; Voxel based morphometry

Indexed keywords

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BASAL GANGLION; CLINICAL FEATURE; COGNITIVE DEFECT; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS CALLOSUM; CROSS-SECTIONAL STUDY; DIAGONAL BAND OF BROCA; DIFFUSION TENSOR IMAGING; DISABILITY; FEMALE; FOLLOW UP; FRACTIONAL ANISOTROPY; FRONTAL LOBE; GENOTYPE; GRAY MATTER; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MOTONEURON; MOTOR CORTEX; NEUROIMAGING; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; PYRAMIDAL TRACT; VOXEL BASED MORPHOMETRY; WHITE MATTER;

BIOMARKER; DIFFUSION TENSOR IMAGING; MAGNETIC RESONANCE IMAGING; MOTOR NEURON DISEASE; VOXEL-BASED MORPHOMETRY;

AMYOTROPHIC LATERAL SCLEROSIS; CEREBRAL CORTEX; COHORT STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVE FIBERS, MYELINATED; NERVE NET;

EID: 84906666492     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awu162     Document Type: Article

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