Variants in nicotinamide adenine dinucleotide phosphate oxidase complex components determine susceptibility to very early onset inflammatory bowel disease

Gastroenterology

Volumn 147, Issue 3, 2014, Pages

  Dhillon, Sandeep S ^a,b   Fattouh, Ramzi ^a   Elkadri, Abdul ^a,b,c   Xu, Wei ^d   Murchie, Ryan ^a   Walters, Thomas ^a,c   Guo, Conghui ^a   Mack, David ^e   Huynh, Hien Q ^f   Baksh, Shairaz ^f   Silverberg, Mark S ^b,d   Griffiths, Anne M ^a,c   Snapper, Scott B ^g   Brumell, John H ^a,b   Muise, Aleixo M ^a,b,c  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^f STOLLERY CHILDREN S HOSPITAL   (Canada)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

CGD; Genetics; Phagocytes; VEOIBD

Indexed keywords

CYTOCHROME B; CYTOCHROME B245; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NITROBLUE TETRAZOLIUM; RAC1 PROTEIN; RAC2 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHRONIC GRANULOMATOUS DISEASE; COHORT ANALYSIS; CYTOSOL; DISEASE PREDISPOSITION; ENDOSCOPY; EXOME; FEMALE; GENE FREQUENCY; GENE MUTATION; GENOTYPE; HEK293 CELL LINE; HISTOLOGY; HUMAN; INFLAMMATORY BOWEL DISEASE; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; PRIORITY JOURNAL; RESPIRATORY BURST; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSIENT TRANSFECTION;

CGD; GENETICS; PHAGOCYTES; VEOIBD;

AGE OF ONSET; CASE-CONTROL STUDIES; CHILD, PRESCHOOL; EXOME; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HETEROZYGOTE; HUMANS; INFLAMMATORY BOWEL DISEASES; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; ONTARIO; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; REACTIVE OXYGEN SPECIES; RISK FACTORS; TRANSFECTION;

EID: 84906541386     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2014.06.005     Document Type: Article

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