Inhibition of adenylyl cyclase type 5 prevents L-DOPA-induced dyskinesia in an animal model of Parkinson's disease

Journal of Neuroscience

Volumn 34, Issue 35, 2014, Pages 11744-11753

  Park, Hye Yeon ^a,b   Kang, Young Mi ^a   Kang, Young ^a   Park, Tae Shin ^a,b   Ryu, Young Kyoung ^a   Hwang, Jung Hwan ^a   Kim, Yong Hoon ^a   Chung, Bong Hyun ^a,c   Nam, Ki Hoan ^a   Kim, Mee Ree ^b   Lee, Chul Ho ^a,c   Han, Pyung Lim ^d   Kim, Kyoung Shim ^a,c  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

^c University of Science and Technology (UST)   (South Korea)

^d Ewha Womans University   (South Korea)

Author keywords

Adenylyl cyclase; Dyskinesia; L DOPA; Parkinson's disease

Indexed keywords

ADENYLATE CYCLASE; BENSERAZIDE; LEVODOPA; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; CYLINDER TEST; DYSKINESIA; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE OVEREXPRESSION; GENOTYPE; GRIP STRENGTH TEST; IMMUNOHISTOCHEMISTRY; INVOLUNTARY MOVEMENT; MALE; MORTALITY; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ULTRACENTRIFUGATION; WESTERN BLOTTING;

ADENYLYL CYCLASE; DYSKINESIA; L-DOPA; PARKINSON'S DISEASE;

ADENYLATE CYCLASE; ANIMALS; ANTIPARKINSON AGENTS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; DYSKINESIA, DRUG-INDUCED; IMMUNOHISTOCHEMISTRY; LEVODOPA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PARKINSONIAN DISORDERS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84906537737     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0864-14.2014     Document Type: Article

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