Sulfamates of methyl triterpenoates are effective and competitive inhibitors of carbonic anhydrase II

European Journal of Medicinal Chemistry

Volumn 86, Issue , 2014, Pages 95-102

  Schwarz, Stefan ^a   Sommerwerk, Sven ^a   Lucas, Susana D ^b   Heller, Lucie ^a   Csuk, René ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

Author keywords

Carbonic anhydrase II; Enzyme inhibition; Sulfamates; Triterpenoic acids

Indexed keywords

ACETAZOLAMIDE; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; METHYL (2ALPHA,3BETA) 2 (AMINOSULFONYLYOXY) MASLINOATE; METHYL (2ALPHA,3BETA) 3 (AMINOSULFONYLYOXY) MASLINOATE; METHYL (3BETA) 3 (AMINOSULFONYLYOXY) 11 OXO OLEANOATE; METHYL (3BETA) 3 (AMINOSULFONYLYOXY) 11 OXO URSOLOATE; METHYL (3BETA) 3 (AMINOSULFONYLYOXY) BETULINOATE; METHYL (3BETA) 3 (AMINOSULFONYLYOXY) GLYCYRRHETINOATE; METHYL (3BETA) 3 (AMINOSULFONYLYOXY) OLEAN 12 EN 39 OATE; METHYL (3BETA) 3 (AMINOSULFONYLYOXY) OLEANOATE; METHYL (3BETA) 3 (AMINOSULFONYLYOXY) PLANTANOATE; METHYL (3BETA) 3 (AMINOSULFONYLYOXY) URSOLOATE; METHYL TRITERPENOATE DERIVATIVE; SULFAMIC ACID DERIVATIVE; UNCLASSIFIED DRUG; SULFAMIC ACID; SULFONIC ACID DERIVATIVE; TRITERPENE;

ANIMAL CELL; ARTICLE; CATTLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; ERYTHROCYTE; IN VITRO STUDY; NONHUMAN; 3T3 CELL LINE; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; HUMAN; METABOLISM; MOLECULAR DOCKING; MOUSE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MICE; MOLECULAR DOCKING SIMULATION; MOLECULAR STRUCTURE; NIH 3T3 CELLS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONIC ACIDS; TRITERPENES;

EID: 84906504562     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.08.051     Document Type: Article

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