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Volumn 21, Issue 9, 2014, Pages 703-711

Tumor necrosis factor-α modulates epithelial mesenchymal transition mediators ZEB2 and S100A4 to promote cholangiocarcinoma progression

Author keywords

Cholangiocarcinoma; Epithelial mesenchymal transition; S100A4; ZEB2

Indexed keywords

CALVASCULIN; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZEB1; TRANSCRIPTION FACTOR ZEB2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; PROTEIN S 100; REPRESSOR PROTEIN; S100A4 PROTEIN, HUMAN; TUMOR MARKER; ZEB1 PROTEIN, HUMAN; ZEB2 PROTEIN, HUMAN;

EID: 84906344780     PISSN: 18686974     EISSN: 18686982     Source Type: Journal    
DOI: 10.1002/jhbp.125     Document Type: Article
Times cited : (35)

References (45)
  • 2
    • 33645302628 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition: New insights in signaling, development, and disease
    • Lee JM, Dedhar S, Kalluri R, Thompson EW,. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol. 2006; 172: 973-981.
    • (2006) J Cell Biol , vol.172 , pp. 973-981
    • Lee, J.M.1    Dedhar, S.2    Kalluri, R.3    Thompson, E.W.4
  • 3
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP,. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer. 2002; 2: 442-454.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 4
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP,. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Rev Mol Cell Biol. 2006; 7: 131-142.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 5
    • 84871402255 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiating properties in head and neck cancer
    • Chu PY, Hu FW, Yu CC, Tsai LL, Yu CH, Wu BC, et al. Epithelial- mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiating properties in head and neck cancer. Oral Oncol. 2013; 49: 34-41.
    • (2013) Oral Oncol , vol.49 , pp. 34-41
    • Chu, P.Y.1    Hu, F.W.2    Yu, C.C.3    Tsai, L.L.4    Yu, C.H.5    Wu, B.C.6
  • 6
    • 79953201570 scopus 로고    scopus 로고
    • TWIST1 is expressed in colorectal carcinomas and predicts patient survival
    • Gomez I, Pena C, Herrera M, Munoz C, Larriba MJ, Garcia V, et al. TWIST1 is expressed in colorectal carcinomas and predicts patient survival. PLoS ONE. 2011; 6: e18023.
    • (2011) PLoS ONE , vol.6
    • Gomez, I.1    Pena, C.2    Herrera, M.3    Munoz, C.4    Larriba, M.J.5    Garcia, V.6
  • 7
    • 84055212063 scopus 로고    scopus 로고
    • Overexpression of ZEB2 at the invasion front of colorectal cancer is an independent prognostic marker and regulates tumor invasion in vitro
    • Kahlert C, Lahes S, Radhakrishnan P, Dutta S, Mogler C, Herpel E, et al. Overexpression of ZEB2 at the invasion front of colorectal cancer is an independent prognostic marker and regulates tumor invasion in vitro. Clin Cancer Res. 2011; 17: 7654-7663.
    • (2011) Clin Cancer Res , vol.17 , pp. 7654-7663
    • Kahlert, C.1    Lahes, S.2    Radhakrishnan, P.3    Dutta, S.4    Mogler, C.5    Herpel, E.6
  • 8
    • 84880260044 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha (TNF-alpha) stimulates the epithelial-mesenchymal transition regulator Snail in cholangiocarcinoma
    • Techasen A, Namwat N, Loilome W, Bungkanjana P, Khuntikeo N, Puapairoj A, et al. Tumor necrosis factor-alpha (TNF-alpha) stimulates the epithelial-mesenchymal transition regulator Snail in cholangiocarcinoma. Med Oncol. 2012; 29: 3083-3091.
    • (2012) Med Oncol , vol.29 , pp. 3083-3091
    • Techasen, A.1    Namwat, N.2    Loilome, W.3    Bungkanjana, P.4    Khuntikeo, N.5    Puapairoj, A.6
  • 9
    • 0036513626 scopus 로고    scopus 로고
    • The snail superfamily of zinc-finger transcription factors
    • Nieto MA,. The snail superfamily of zinc-finger transcription factors. Nat Rev Mol Cell Biol. 2002; 3: 155-166.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 155-166
    • Nieto, M.A.1
  • 10
    • 63049101157 scopus 로고    scopus 로고
    • The role of the ZEB family of transcription factors in development and disease
    • Vandewalle C, Van Roy F, Berx G,. The role of the ZEB family of transcription factors in development and disease. Cell Mol Life Sci. 2009; 66: 773-787.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 773-787
    • Vandewalle, C.1    Van Roy, F.2    Berx, G.3
  • 11
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell. 2004; 117: 927-939.
    • (2004) Cell , vol.117 , pp. 927-939
    • Yang, J.1    Mani, S.A.2    Donaher, J.L.3    Ramaswamy, S.4    Itzykson, R.A.5    Come, C.6
  • 12
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesenchymal transitions
    • Zeisberg M, Neilson EG,. Biomarkers for epithelial-mesenchymal transitions. J Clin Invest. 2009; 119: 1429-1437.
    • (2009) J Clin Invest , vol.119 , pp. 1429-1437
    • Zeisberg, M.1    Neilson, E.G.2
  • 13
    • 84863609332 scopus 로고    scopus 로고
    • ZEB2 promotes the metastasis of gastric cancer and modulates epithelial mesenchymal transition of gastric cancer cells
    • Dai YH, Tang YP, Zhu HY, Lv L, Chu Y, Zhou YQ, et al. ZEB2 promotes the metastasis of gastric cancer and modulates epithelial mesenchymal transition of gastric cancer cells. Dig Dis Sci. 2012; 57: 1253-1260.
    • (2012) Dig Dis Sci , vol.57 , pp. 1253-1260
    • Dai, Y.H.1    Tang, Y.P.2    Zhu, H.Y.3    Lv, L.4    Chu, Y.5    Zhou, Y.Q.6
  • 14
    • 78049339481 scopus 로고    scopus 로고
    • Small interfering RNA-directed knockdown of S100A4 decreases proliferation and invasiveness of osteosarcoma cells
    • Ma X, Yang Y, Wang Y, An G, Lv G,. Small interfering RNA-directed knockdown of S100A4 decreases proliferation and invasiveness of osteosarcoma cells. Cancer Lett. 2010; 299: 171-181.
    • (2010) Cancer Lett , vol.299 , pp. 171-181
    • Ma, X.1    Yang, Y.2    Wang, Y.3    An, G.4    Lv, G.5
  • 15
    • 33749516823 scopus 로고    scopus 로고
    • S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9
    • Saleem M, Kweon MH, Johnson JJ, Adhami VM, Elcheva I, Khan N, et al. S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9. Proc Natl Acad Sci USA. 2006; 103: 14825-14830.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 14825-14830
    • Saleem, M.1    Kweon, M.H.2    Johnson, J.J.3    Adhami, V.M.4    Elcheva, I.5    Khan, N.6
  • 16
    • 33847223125 scopus 로고    scopus 로고
    • Modified expression of Mts1/S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo
    • Takenaga K, Nygren J, Zelenina M, Ohira M, Iuchi T, Lukanidin E, et al. Modified expression of Mts1/S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo. Neurobiol Dis. 2007; 25: 455-463.
    • (2007) Neurobiol Dis , vol.25 , pp. 455-463
    • Takenaga, K.1    Nygren, J.2    Zelenina, M.3    Ohira, M.4    Iuchi, T.5    Lukanidin, E.6
  • 17
    • 84868468237 scopus 로고    scopus 로고
    • S100A4 regulates motility and invasiveness of human esophageal squamous cell carcinoma through modulating the AKT/Slug signal pathway
    • Zhang K, Zhang M, Zhao H, Yan B, Zhang D, Liang J,. S100A4 regulates motility and invasiveness of human esophageal squamous cell carcinoma through modulating the AKT/Slug signal pathway. Dis Esophagus. 2012; 25: 731-739.
    • (2012) Dis Esophagus , vol.25 , pp. 731-739
    • Zhang, K.1    Zhang, M.2    Zhao, H.3    Yan, B.4    Zhang, D.5    Liang, J.6
  • 18
    • 84876498615 scopus 로고    scopus 로고
    • Tumour-microenvironment interactions: Role of tumour stroma and proteins produced by cancer-associated fibroblasts in chemotherapy response
    • Hale MD, Hayden JD, Grabsch HI,. Tumour-microenvironment interactions: role of tumour stroma and proteins produced by cancer-associated fibroblasts in chemotherapy response. Cell Oncol. 2013; 36: 95-112.
    • (2013) Cell Oncol , vol.36 , pp. 95-112
    • Hale, M.D.1    Hayden, J.D.2    Grabsch, H.I.3
  • 19
    • 76949084622 scopus 로고    scopus 로고
    • TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion
    • Wu Y, Zhou BP,. TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion. Br J Cancer. 2010; 102: 639-644.
    • (2010) Br J Cancer , vol.102 , pp. 639-644
    • Wu, Y.1    Zhou, B.P.2
  • 20
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill F,. Tumour necrosis factor and cancer. Nat Rev Cancer. 2009; 9: 361-371.
    • (2009) Nat Rev Cancer , vol.9 , pp. 361-371
    • Balkwill, F.1
  • 21
    • 13944271340 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha promotes invasiveness of cholangiocarcinoma cells via its receptor, TNFR2
    • Tanimura Y, Kokuryo T, Tsunoda N, Yamazaki Y, Oda K, Nimura Y, et al. Tumor necrosis factor alpha promotes invasiveness of cholangiocarcinoma cells via its receptor, TNFR2. Cancer Lett. 2005; 219: 205-213.
    • (2005) Cancer Lett , vol.219 , pp. 205-213
    • Tanimura, Y.1    Kokuryo, T.2    Tsunoda, N.3    Yamazaki, Y.4    Oda, K.5    Nimura, Y.6
  • 22
    • 0037572319 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids
    • Bates RC, Mercurio AM,. Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids. Mol Biol Cell. 2003; 14: 1790-1800.
    • (2003) Mol Biol Cell , vol.14 , pp. 1790-1800
    • Bates, R.C.1    Mercurio, A.M.2
  • 23
    • 3042554386 scopus 로고    scopus 로고
    • Cell-matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca(2+) influx and PKC activation
    • Nagano O, Murakami D, Hartmann D, De Strooper B, Saftig P, Iwatsubo T, et al. Cell-matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca(2+) influx and PKC activation. J Cell Biol. 2004; 165: 893-902.
    • (2004) J Cell Biol , vol.165 , pp. 893-902
    • Nagano, O.1    Murakami, D.2    Hartmann, D.3    De Strooper, B.4    Saftig, P.5    Iwatsubo, T.6
  • 24
    • 33646472252 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha as a tumour promoter
    • Szlosarek P, Charles KA, Balkwill FR,. Tumour necrosis factor-alpha as a tumour promoter. Eur J Cancer. 2006; 42: 745-750.
    • (2006) Eur J Cancer , vol.42 , pp. 745-750
    • Szlosarek, P.1    Charles, K.A.2    Balkwill, F.R.3
  • 25
    • 0035153391 scopus 로고    scopus 로고
    • Translational regulation of renal proximal tubular epithelial cell transforming growth factor-beta1 generation by insulin
    • Morrisey K, Evans RA, Wakefield L, Phillips AO,. Translational regulation of renal proximal tubular epithelial cell transforming growth factor-beta1 generation by insulin. Am J Pathol. 2001; 159: 1905-1915.
    • (2001) Am J Pathol , vol.159 , pp. 1905-1915
    • Morrisey, K.1    Evans, R.A.2    Wakefield, L.3    Phillips, A.O.4
  • 26
    • 0026652797 scopus 로고
    • Regulation of rat pulmonary artery endothelial cell transforming growth factor-beta production by IL-1 beta and tumor necrosis factor-alpha
    • Phan SH, Gharaee-Kermani M, McGarry B, Kunkel SL, Wolber FW,. Regulation of rat pulmonary artery endothelial cell transforming growth factor-beta production by IL-1 beta and tumor necrosis factor-alpha. J Immunol. 1992; 149: 103-106.
    • (1992) J Immunol , vol.149 , pp. 103-106
    • Phan, S.H.1    Gharaee-Kermani, M.2    McGarry, B.3    Kunkel, S.L.4    Wolber, F.W.5
  • 27
    • 0029856324 scopus 로고    scopus 로고
    • Induction of TGF-beta 1 synthesis in d-glucose primed human proximal tubular cells by IL-1 beta and TNF alpha
    • Phillips AO, Topley N, Steadman R, Morrisey K, Williams JD,. Induction of TGF-beta 1 synthesis in d-glucose primed human proximal tubular cells by IL-1 beta and TNF alpha. Kidney Int. 1996; 50: 1546-1554.
    • (1996) Kidney Int , vol.50 , pp. 1546-1554
    • Phillips, A.O.1    Topley, N.2    Steadman, R.3    Morrisey, K.4    Williams, J.D.5
  • 28
    • 45849148542 scopus 로고    scopus 로고
    • The latent form of TGFbeta(1) is induced by TNFalpha through an ERK specific pathway and is activated by asbestos-derived reactive oxygen species in vitro and in vivo
    • Sullivan DE, Ferris M, Pociask D, Brody AR,. The latent form of TGFbeta(1) is induced by TNFalpha through an ERK specific pathway and is activated by asbestos-derived reactive oxygen species in vitro and in vivo. J Immunotoxicol. 2008; 5: 145-149.
    • (2008) J Immunotoxicol , vol.5 , pp. 145-149
    • Sullivan, D.E.1    Ferris, M.2    Pociask, D.3    Brody, A.R.4
  • 29
    • 16444383682 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces transforming growth factor-beta1 expression in lung fibroblasts through the extracellular signal-regulated kinase pathway
    • Sullivan DE, Ferris M, Pociask D, Brody AR,. Tumor necrosis factor-alpha induces transforming growth factor-beta1 expression in lung fibroblasts through the extracellular signal-regulated kinase pathway. Am J Respir Cell Mol Biol. 2005; 32: 342-349.
    • (2005) Am J Respir Cell Mol Biol , vol.32 , pp. 342-349
    • Sullivan, D.E.1    Ferris, M.2    Pociask, D.3    Brody, A.R.4
  • 30
    • 22244492306 scopus 로고    scopus 로고
    • Carcinoma invasion and metastasis: A role for epithelial-mesenchymal transition?
    • discussion 5.
    • Thompson EW, Newgreen DF, Tarin D,. Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition? Cancer Res. 2005; 65: 5991-5995; discussion 5.
    • (2005) Cancer Res , vol.65 , pp. 5991-5995
    • Thompson, E.W.1    Newgreen, D.F.2    Tarin, D.3
  • 32
    • 84860601923 scopus 로고    scopus 로고
    • Single cell profiling of circulating tumor cells: Transcriptional heterogeneity and diversity from breast cancer cell lines
    • Powell AA, Talasaz AH, Zhang H, Coram MA, Reddy A, Deng G, et al. Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines. PLoS ONE. 2012; 7: e33788.
    • (2012) PLoS ONE , vol.7
    • Powell, A.A.1    Talasaz, A.H.2    Zhang, H.3    Coram, M.A.4    Reddy, A.5    Deng, G.6
  • 33
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • Batlle E, Sancho E, Franci C, Dominguez D, Monfar M, Baulida J, et al. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat Cell Biol. 2000; 2: 84-89.
    • (2000) Nat Cell Biol , vol.2 , pp. 84-89
    • Batlle, E.1    Sancho, E.2    Franci, C.3    Dominguez, D.4    Monfar, M.5    Baulida, J.6
  • 34
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A, Perez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG, et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol. 2000; 2: 76-83.
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3    Locascio, A.4    Blanco, M.J.5    Del Barrio, M.G.6
  • 35
    • 0037131409 scopus 로고    scopus 로고
    • Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression
    • Guaita S, Puig I, Franci C, Garrido M, Dominguez D, Batlle E, et al. Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression. J Biol Chem. 2002; 277: 39209-39216.
    • (2002) J Biol Chem , vol.277 , pp. 39209-39216
    • Guaita, S.1    Puig, I.2    Franci, C.3    Garrido, M.4    Dominguez, D.5    Batlle, E.6
  • 36
    • 0037086277 scopus 로고    scopus 로고
    • The SLUG zinc-finger protein represses E-cadherin in breast cancer
    • Hajra KM, Chen DY, Fearon ER,. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res. 2002; 62: 1613-1618.
    • (2002) Cancer Res , vol.62 , pp. 1613-1618
    • Hajra, K.M.1    Chen, D.Y.2    Fearon, E.R.3
  • 37
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • Peinado H, Olmeda D, Cano A,. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer. 2007; 7: 415-428.
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 38
    • 0035920152 scopus 로고    scopus 로고
    • A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions
    • Perez-Moreno MA, Locascio A, Rodrigo I, Dhondt G, Portillo F, Nieto MA, et al. A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions. J Biol Chem. 2001; 276: 27424-27431.
    • (2001) J Biol Chem , vol.276 , pp. 27424-27431
    • Perez-Moreno, M.A.1    Locascio, A.2    Rodrigo, I.3    Dhondt, G.4    Portillo, F.5    Nieto, M.A.6
  • 39
    • 4644245551 scopus 로고    scopus 로고
    • Tumor metastasis: A new twist on epithelial-mesenchymal transitions
    • Vernon AE, LaBonne C,. Tumor metastasis: a new twist on epithelial-mesenchymal transitions. Curr Biol. 2004; 14: R719-721.
    • (2004) Curr Biol , vol.14
    • Vernon, A.E.1    Labonne, C.2
  • 40
  • 42
    • 84880665353 scopus 로고    scopus 로고
    • Clinicopathological significance of S100 protein expression in cholangiocarcinoma
    • Sato Y, Harada K, Sasaki M, Nakanuma Y,. Clinicopathological significance of S100 protein expression in cholangiocarcinoma. J Gastroenterol Hepatol. 2013; 28: 1422-1429.
    • (2013) J Gastroenterol Hepatol , vol.28 , pp. 1422-1429
    • Sato, Y.1    Harada, K.2    Sasaki, M.3    Nakanuma, Y.4
  • 43
    • 80051976226 scopus 로고    scopus 로고
    • Nuclear expression of S100A4 calcium-binding protein increases cholangiocarcinoma invasiveness and metastasization
    • Fabris L, Cadamuro M, Moserle L, Dziura J, Cong X, Sambado L, et al. Nuclear expression of S100A4 calcium-binding protein increases cholangiocarcinoma invasiveness and metastasization. Hepatology. 2011; 54: 890-899.
    • (2011) Hepatology , vol.54 , pp. 890-899
    • Fabris, L.1    Cadamuro, M.2    Moserle, L.3    Dziura, J.4    Cong, X.5    Sambado, L.6
  • 45
    • 34548496683 scopus 로고    scopus 로고
    • Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta
    • Shirakihara T, Saitoh M, Miyazono K,. Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta. Mol Biol Cell. 2007; 18: 3533-3544.
    • (2007) Mol Biol Cell , vol.18 , pp. 3533-3544
    • Shirakihara, T.1    Saitoh, M.2    Miyazono, K.3


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