Recent H3N2 influenza virus clinical isolates rapidly acquire hemagglutinin or neuraminidase mutations when propagated for antigenic analyses

Journal of Virology

Volumn 88, Issue 18, 2014, Pages 10986-10989

  Chambers, Benjamin S ^a,b   Li, Yang ^a,b   Hodink, Richard L ^b   Hensley, Scott E ^a,b  

^a WISTAR INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; OSELTAMIVIR; VIRUS HEMAGGLUTININ; VIRUS SIALIDASE; INFLUENZA VIRUS HEMAGGLUTININ; SIALIDASE;

ANIMAL CELL; ANTIGENICITY; ARTICLE; BRONCHUS SECRETION; CULTURE MEDIUM; GENE SEQUENCE; IN VITRO STUDY; INFLUENZA VIRUS A H3N2; MDCK CELL LINE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE GENETICS; SEROLOGY; VIRAL PHENOMENA AND FUNCTIONS; VIRUS ATTACHMENT; VIRUS CELL INTERACTION; VIRUS CULTURE; VIRUS GENE; VIRUS IDENTIFICATION; VIRUS ISOLATION; VIRUS LOAD; VIRUS MUTATION; VIRUS PROPAGATION; VIRUS REPLICATION; VIRUS STRAIN; ANIMAL; ANTIGENIC VARIATION; CHILD; ENZYMOLOGY; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; INFLUENZA; ISOLATION AND PURIFICATION; MALE; MISSENSE MUTATION; MOLECULAR GENETICS; VIROLOGY;

ANIMALS; ANTIGENIC VARIATION; CHILD; FEMALE; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA, HUMAN; MALE; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; NEURAMINIDASE; SERIAL PASSAGE; VIRUS CULTIVATION;

EID: 84906330420     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01077-14     Document Type: Article

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