Single Hemagglutinin Mutations That Alter both Antigenicity and Receptor Binding Avidity Influence Influenza Virus Antigenic Clustering

Journal of Virology

Volumn 87, Issue 17, 2013, Pages 9904-9910

  Li, Yang ^a,b   Bostick, David L ^b   Sullivan, Colleen B ^a   Myers, Jaclyn L ^a   Griesemer, Sara B ^c   George, Kirsten St ^c   Plotkin, Joshua B ^b   Hensley, Scott E ^a,b  

^a WISTAR INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WADSWORTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; EPITOPE; INFLUENZA VIRUS HEMAGGLUTININ; VIRUS ANTIGEN; VIRUS RECEPTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIBODY RESPONSE; ANTIGEN BINDING; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; HEMAGGLUTINATION INHIBITION TEST; IMMUNOREACTIVITY; INFLUENZA VIRUS A H3N2; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR AFFINITY; REVERSE GENETICS; VIRUS ATTACHMENT; VIRUS IDENTIFICATION; VIRUS MUTATION; VIRUS STRAIN;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; EPITOPE MAPPING; FERRETS; GENES, VIRAL; HEMAGGLUTINATION INHIBITION TESTS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; IMMUNODOMINANT EPITOPES; INFLUENZA A VIRUS, H3N2 SUBTYPE; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; RECEPTORS, VIRUS; TURKEYS; VIRUS ATTACHMENT;

EID: 84883300838     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01023-13     Document Type: Article

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