The importance of helix p1 stability for structural pre-organization and ligand binding affinity of the adenine riboswitch aptamer domain

RNA Biology

Volumn 11, Issue 5, 2014, Pages 655-666

  Nozinovic, Senada ^a,b   Reining, Anke ^a,b   Kim, Yong Boum ^a,b   Noeske, Jonas ^b   Schlepckow, Kai ^a,b   Woḧnert, Jens ^a,c   Schwalbe, Harald ^a,b  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Institute of Molecular Biosciences   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; APTAMER; HYDROGEN; NUCLEOTIDE; OLIGONUCLEOTIDE; PURINE; BACTERIAL RNA; LIGAND; MAGNESIUM; RIBOSWITCH;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DISSOCIATION; FLUORESCENCE SPECTROSCOPY; HELIX P1; HIGH TEMPERATURE; HYDROGEN BOND; IN VITRO STUDY; KINETICS; LIGAND BINDING; LOW TEMPERATURE; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; RIBOSWITCH; RNA CONFORMATION; RNA STABILITY; RNA STRUCTURE; SIGNAL TRANSDUCTION; THERMODYNAMICS; THERMOSTABILITY; BASE PAIRING; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; GENETICS; METABOLISM;

ADENINE; APTAMERS, NUCLEOTIDE; BASE PAIRING; LIGANDS; MAGNESIUM; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; RIBOSWITCH; RNA STABILITY; RNA, BACTERIAL; THERMODYNAMICS;

EID: 84906329914     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.29439     Document Type: Article

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