메뉴 건너뛰기




Volumn 33, Issue 33, 2014, Pages 4213-4225

Estrogen receptor β upregulates FOXO3a and causes induction of apoptosis through PUMA in prostate cancer

Author keywords

apoptosis; ER ; FOXO3a; p53; PUMA

Indexed keywords

CASPASE 9; CYTOCHROME C; ESTROGEN RECEPTOR BETA; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; PUMA PROTEIN; TRANSCRIPTION FACTOR FKHRL1;

EID: 84906283646     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.384     Document Type: Article
Times cited : (100)

References (43)
  • 2
    • 47949126042 scopus 로고    scopus 로고
    • FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells
    • Cornforth AN, Davis JS, Khanifar E, Nastiuk KL, Krolewski JJ. FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells. Oncogene 2008; 27: 4422-4433.
    • (2008) Oncogene , vol.27 , pp. 4422-4433
    • Cornforth, A.N.1    Davis, J.S.2    Khanifar, E.3    Nastiuk, K.L.4    Krolewski, J.J.5
  • 3
    • 0035265823 scopus 로고    scopus 로고
    • PUMA induces the rapid apoptosis of colorectal cancer cells
    • DOI 10.1016/S1097-2765(01)00213-1
    • Yu J, Zhang L, Hwang PM, Kinzler KW, Vogelstein B. PUMA induces the rapid apoptosis of colorectal cancer cells. Mol Cell 2001; 7: 673-682. (Pubitemid 32706358)
    • (2001) Molecular Cell , vol.7 , Issue.3 , pp. 673-682
    • Yu, J.1    Zhang, L.2    Hwang, P.M.3    Kinzler, K.W.4    Vogelstein, B.5
  • 7
    • 79751488378 scopus 로고    scopus 로고
    • MiR-155, a modulator of FOXO3a protein expression, is underexpressed and cannot be upregulated by stimulation of HOZOT, a line of multifunctional Treg
    • Yamamoto M, Kondo E, Takeuchi M, Harashima A, Otani T, Tsuji-Takayama K et al. miR-155, a modulator of FOXO3a protein expression, is underexpressed and cannot be upregulated by stimulation of HOZOT, a line of multifunctional Treg. PLoS One 2011; 6: e16841.
    • (2011) PLoS One , vol.6
    • Yamamoto, M.1    Kondo, E.2    Takeuchi, M.3    Harashima, A.4    Otani, T.5    Tsuji-Takayama, K.6
  • 8
    • 44849127978 scopus 로고    scopus 로고
    • Forkhead box transcription factor FOXO3a suppresses estrogen-dependent breast cancer cell proliferation and tumorigenesis
    • Zou Y, Tsai WB, Cheng CJ, Hsu C, Chung YM, Li PC et al. Forkhead box transcription factor FOXO3a suppresses estrogen-dependent breast cancer cell proliferation and tumorigenesis. Breast Cancer Res 2008; 10: R21.
    • (2008) Breast Cancer Res , vol.10
    • Zou, Y.1    Tsai, W.B.2    Cheng, C.J.3    Hsu, C.4    Chung, Y.M.5    Li, P.C.6
  • 9
    • 79953773923 scopus 로고    scopus 로고
    • Chemopreventive effect of ERbeta-Selective agonist on intestinal tumorigenesis in Apc(Min/+) mice
    • Giroux V, Bernatchez G, Carrier JC. Chemopreventive effect of ERbeta-Selective agonist on intestinal tumorigenesis in Apc(Min/+) mice. Mol Carcinogen 2011; 50: 359-369.
    • (2011) Mol Carcinogen , vol.50 , pp. 359-369
    • Giroux, V.1    Bernatchez, G.2    Carrier, J.C.3
  • 12
    • 84865423001 scopus 로고    scopus 로고
    • Aggressive prostate cancer is prevented in ERalphaKO mice and stimulated in ERbetaKO TRAMP mice
    • Slusarz A, Jackson GA, Day JK, Shenouda NS, Bogener JL, Browning JD et al. Aggressive prostate cancer is prevented in ERalphaKO mice and stimulated in ERbetaKO TRAMP mice. Endocrinology 2012; 153: 4160-4170.
    • (2012) Endocrinology , vol.153 , pp. 4160-4170
    • Slusarz, A.1    Jackson, G.A.2    Day, J.K.3    Shenouda, N.S.4    Bogener, J.L.5    Browning, J.D.6
  • 13
    • 84866132321 scopus 로고    scopus 로고
    • Potential role of estrogen receptor Beta as a tumor suppressor of epithelial ovarian cancer
    • Bossard C, Busson M, Vindrieux D, Gaudin F, Machelon V, Brigitte M et al. Potential role of estrogen receptor Beta as a tumor suppressor of epithelial ovarian cancer. PLoS One 2012; 7: e44787.
    • (2012) PLoS One , vol.7
    • Bossard, C.1    Busson, M.2    Vindrieux, D.3    Gaudin, F.4    Machelon, V.5    Brigitte, M.6
  • 14
    • 84870316458 scopus 로고    scopus 로고
    • Estrogen receptors beta1 and beta2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3
    • Dey P, Jonsson P, Hartman J, Williams C, Ström A, Gustafsson JÅ et al. Estrogen receptors beta1 and beta2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3. Mol Endocrinol 2012; 26: 1991-2003.
    • (2012) Mol Endocrinol , vol.26 , pp. 1991-2003
    • Dey, P.1    Jonsson, P.2    Hartman, J.3    Williams, C.4    Ström, A.5    Gustafsson, J.A.6
  • 15
  • 17
    • 77649253043 scopus 로고    scopus 로고
    • Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated
    • McPherson SJ, Hussain S, Balanathan P, Hedwards SL, Niranjan B, Grant M et al. Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated. Proc Natl Acad Sci USA 2010; 107: 3123-3128.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 3123-3128
    • McPherson, S.J.1    Hussain, S.2    Balanathan, P.3    Hedwards, S.L.4    Niranjan, B.5    Grant, M.6
  • 18
    • 84863694293 scopus 로고    scopus 로고
    • Estrogen receptor beta activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations
    • Hussain S, Lawrence MG, Taylor RA, Lo CY, Frydenberg M, Risbridger GP et al. Estrogen receptor beta activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations. PLoS One 2012; 7: e40732.
    • (2012) PLoS One , vol.7
    • Hussain, S.1    Lawrence, M.G.2    Taylor, R.A.3    Lo, C.Y.4    Frydenberg, M.5    Risbridger, G.P.6
  • 19
    • 43149093785 scopus 로고    scopus 로고
    • Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells
    • DOI 10.1007/s10549-007-9640-6
    • Hodges-Gallagher L, Valentine CD, El Bader S, Kushner PJ. Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells. Breast Cancer Res Treat 2008; 109: 241-250. (Pubitemid 351644839)
    • (2008) Breast Cancer Research and Treatment , vol.109 , Issue.2 , pp. 241-250
    • Hodges-Gallagher, L.1    Valentine, C.D.2    Bader, S.E.3    Kushner, P.J.4
  • 20
    • 10944251851 scopus 로고    scopus 로고
    • Frequent loss of estrogen and progesterone receptors in human prostatic tumors determined by quantitative real-time PCR
    • DOI 10.1016/j.mce.2004.08.012, PII S0303720704003375
    • Ji Q, Liu PI, Elshimali Y, Stolz A. Frequent loss of estrogen and progesterone receptors in human prostatic tumors determined by quantitative real-time PCR. Mol Cell Endocrinol 2005; 229: 103-110. (Pubitemid 40018088)
    • (2005) Molecular and Cellular Endocrinology , vol.229 , Issue.1-2 , pp. 103-110
    • Ji, Q.1    Liu, P.I.2    Elshimali, Y.3    Stolz, A.4
  • 21
    • 77956363192 scopus 로고    scopus 로고
    • Estrogen receptor beta2 and beta5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion
    • Leung YK, Lam HM, Wu S, Song D, Levin L, Cheng L et al. Estrogen receptor beta2 and beta5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion. Endocrine Relat Cancer 2010; 17: 675-689.
    • (2010) Endocrine Relat Cancer , vol.17 , pp. 675-689
    • Leung, Y.K.1    Lam, H.M.2    Wu, S.3    Song, D.4    Levin, L.5    Cheng, L.6
  • 22
    • 35348931001 scopus 로고    scopus 로고
    • 5α-Androstane-3β,17β-diol (3β-diol), an estrogenic metabolite of 5α-dihydrotestosterone, is a potent modulator of estrogen receptor ERβ expression in the ventral prostrate of adult rats
    • DOI 10.1016/j.steroids.2007.08.001, PII S0039128X07001365
    • Oliveira AG, Coelho PH, Guedes FD, Mahecha GA, Hess RA, Oliveira CA et al. 5alpha-Androstane-3beta,17beta-diol (3beta-diol), an estrogenic metabolite of 5alpha-dihydrotestosterone, is a potent modulator of estrogen receptor ERbeta expression in the ventral prostrate of adult rats. Steroids 2007; 72: 914-922. (Pubitemid 47600274)
    • (2007) Steroids , vol.72 , Issue.14 , pp. 914-922
    • Oliveira, A.G.1    Coelho, P.H.2    Guedes, F.D.3    Mahecha, G.A.B.4    Hess, R.A.5    Oliveira, C.A.6
  • 24
    • 0033604585 scopus 로고    scopus 로고
    • The regulation and activities of the multifunctional serine/ threonine kinase Akt/PKB
    • Kandel ES, Hay N. The regulation and activities of the multifunctional serine/ threonine kinase Akt/PKB. Exp Cell Res 1999; 253: 210-229.
    • (1999) Exp Cell Res , vol.253 , pp. 210-229
    • Kandel, E.S.1    Hay, N.2
  • 25
    • 27844497945 scopus 로고    scopus 로고
    • FOXO transcription factors at the interface between longevity and tumor suppression
    • DOI 10.1038/sj.onc.1209086, PII 1209086
    • Greer EL, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 2005; 24: 7410-7425. (Pubitemid 41637981)
    • (2005) Oncogene , vol.24 , Issue.50 , pp. 7410-7425
    • Greer, E.L.1    Brunet, A.2
  • 28
    • 32444436779 scopus 로고    scopus 로고
    • Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression
    • DOI 10.1016/j.molcel.2006.01.014, PII S1097276506000347
    • Cvoro A, Tzagarakis-Foster C, Tatomer D, Paruthiyil S, Fox MS, Leitman DC et al. Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression. Mol Cell 2006; 21: 555-564. (Pubitemid 43228010)
    • (2006) Molecular Cell , vol.21 , Issue.4 , pp. 555-564
    • Cvoro, A.1    Tzagarakis-Foster, C.2    Tatomer, D.3    Paruthiyil, S.4    Fox, M.S.5    Leitman, D.C.6
  • 29
    • 61749095503 scopus 로고    scopus 로고
    • The dual, opposing roles of estrogen in the prostate
    • Ellem SJ, Risbridger GP. The dual, opposing roles of estrogen in the prostate. Ann NY Acad Sci 2009; 1155: 174-186.
    • (2009) Ann NY Acad Sci , vol.1155 , pp. 174-186
    • Ellem, S.J.1    Risbridger, G.P.2
  • 30
    • 77950476293 scopus 로고    scopus 로고
    • ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: Implications for Gleason grading
    • Mak P, Leav I, Pursell B, Bae D, Yang X, Taglienti CA et al. ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading. Cancer Cell 2010; 17: 319-332.
    • (2010) Cancer Cell , vol.17 , pp. 319-332
    • Mak, P.1    Leav, I.2    Pursell, B.3    Bae, D.4    Yang, X.5    Taglienti, C.A.6
  • 32
    • 79955788943 scopus 로고    scopus 로고
    • An ADIOL-ERbeta-CtBP transrepression pathway negatively regulates microglia-mediated inflammation
    • Saijo K, Collier JG, Li AC, Katzenellenbogen JA, Glass CK. An ADIOL-ERbeta-CtBP transrepression pathway negatively regulates microglia-mediated inflammation. Cell 2011; 145: 584-595.
    • (2011) Cell , vol.145 , pp. 584-595
    • Saijo, K.1    Collier, J.G.2    Li, A.C.3    Katzenellenbogen, J.A.4    Glass, C.K.5
  • 33
    • 84055187654 scopus 로고    scopus 로고
    • Estrogen receptor beta and 17beta-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer
    • Muthusamy S, Andersson S, Kim HJ, Butler R, Waage L, Gustafsson JÅ et al. Estrogen receptor beta and 17beta-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer. Proc Natl Acad Sci USA 2011; 108: 20090-20094.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 20090-20094
    • Muthusamy, S.1    Andersson, S.2    Kim, H.J.3    Butler, R.4    Waage, L.5    Gustafsson, J.A.6
  • 34
    • 34548748656 scopus 로고    scopus 로고
    • Regulation and expression of human CYP7B1 in prostate: Overexpression of CYP7B1 during progression of prostatic adenocarcinoma
    • DOI 10.1002/pros.20630
    • Olsson M, Gustafsson O, Skogastierna C, Tolf A, Rietz BD, Morfin R et al. Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma. Prostate 2007; 67: 1439-1446. (Pubitemid 47435790)
    • (2007) Prostate , vol.67 , Issue.13 , pp. 1439-1446
    • Olsson, M.1    Gustafsson, O.2    Skogastierna, C.3    Tolf, A.4    Du Rietz, B.5    Morfin, R.6    Rane, A.7    Ekstrom, L.8
  • 35
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • DOI 10.1016/S1097-2765(01)00214-3
    • Nakano K, Vousden KH. PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 2001; 7: 683-694. (Pubitemid 32706359)
    • (2001) Molecular Cell , vol.7 , Issue.3 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 36
    • 79960371728 scopus 로고    scopus 로고
    • Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsiveness in breast cancer
    • Roberts CG, Millar EK, O'Toole SA, McNeil CM, Lehrbach GM, Pinese M et al. Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsiveness in breast cancer. Oncogene 2011; 30: 3186-3197.
    • (2011) Oncogene , vol.30 , pp. 3186-3197
    • Roberts, C.G.1    Millar, E.K.2    O'toole, S.A.3    McNeil, C.M.4    Lehrbach, G.M.5    Pinese, M.6
  • 37
    • 33845762296 scopus 로고    scopus 로고
    • Estrogen receptor β inhibits angiogenesis and growth of T47D breast cancer xenografts
    • DOI 10.1158/0008-5472.CAN-06-0017
    • Hartman J, Lindberg K, Morani A, Inzunza J, Ström A, Gustafsson JA et al. Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts. Cancer Res 2006; 66: 11207-11213. (Pubitemid 46009948)
    • (2006) Cancer Research , vol.66 , Issue.23 , pp. 11207-11213
    • Hartman, J.1    Lindberg, K.2    Morani, A.3    Inzunza, J.4    Strom, A.5    Gustafsson, J.-A.6
  • 38
    • 68049129874 scopus 로고    scopus 로고
    • Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells
    • Hartman J, Edvardsson K, Lindberg K, Zhao C, Williams C, Ström A et al. Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells. Cancer Res 2009; 69: 6100-6106.
    • (2009) Cancer Res , vol.69 , pp. 6100-6106
    • Hartman, J.1    Edvardsson, K.2    Lindberg, K.3    Zhao, C.4    Williams, C.5    Ström, A.6
  • 40
    • 66449130218 scopus 로고    scopus 로고
    • Endothelial NOS, estrogen receptor beta, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer
    • Nanni S, Benvenuti V, Grasselli A, Priolo C, Aiello A, Mattiussi S et al. Endothelial NOS, estrogen receptor beta, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer. J Clin Invest 2009; 119: 1093-1108.
    • (2009) J Clin Invest , vol.119 , pp. 1093-1108
    • Nanni, S.1    Benvenuti, V.2    Grasselli, A.3    Priolo, C.4    Aiello, A.5    Mattiussi, S.6
  • 41
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983; 11: 1475-1489.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 42
    • 10044271901 scopus 로고    scopus 로고
    • HES-1 inhibits 17β-estradiol and heregulin-β1-mediated upregulation of E2F-1
    • DOI 10.1038/sj.onc.1208139
    • Hartman J, Müller P, Foster JS, Wimalasena J, Gustafsson JA, Ström A et al. HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1. Oncogene 2004; 23: 8826-8833. (Pubitemid 39610444)
    • (2004) Oncogene , vol.23 , Issue.54 , pp. 8826-8833
    • Hartman, J.1    Muller, P.2    Foster, J.S.3    Wimalasena, J.4    Gustafsson, J.-A.5    Strom, A.6
  • 43
    • 33745186905 scopus 로고    scopus 로고
    • DAX-1 expression is regulated during mammary epithelial cell differentiation
    • DOI 10.1210/en.2005-1651
    • Helguero LA, Hedengran Faulds M, Forster C, Gustafsson JA, Haldosen LA. DAX-1 expression is regulated during mammary epithelial cell differentiation. Endocrinology 2006; 147: 3249-3259. (Pubitemid 43904302)
    • (2006) Endocrinology , vol.147 , Issue.7 , pp. 3249-3259
    • Helguero, L.A.1    Faulds, M.H.2    Forster, C.3    Gustafsson, J.-A.4    Haldosen, L.-A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.