-
1
-
-
73949110360
-
Pharmacogenomic progress in individualized dosing of key drugs for cancer patients
-
Walko CM, McLeod H: Pharmacogenomic progress in individualized dosing of key drugs for cancer patients. Nat Clin Pract Oncol 6:153-162, 2009
-
(2009)
Nat Clin Pract Oncol
, vol.6
, pp. 153-162
-
-
Walko, C.M.1
McLeod, H.2
-
2
-
-
0029743058
-
Dose calculation of anticancer drugs: A review of the current practice and introduction of an alternative
-
Gurney H: Dose calculations of anticancer drugs: A review of the current practice and introduction of an alternative. J Clin Oncol 14:2590-2611, 1996 (Pubitemid 26300128)
-
(1996)
Journal of Clinical Oncology
, vol.14
, Issue.9
, pp. 2590-2611
-
-
Gurney, H.1
-
3
-
-
0003964361
-
-
American Cancer Society: Atlanta, GA, American Cancer Society
-
American Cancer Society: Cancer Facts and Figures 2013. Atlanta, GA, American Cancer Society, 2013
-
(2013)
Cancer Facts and Figures 2013
-
-
-
4
-
-
0038662715
-
Participation of patients 65 years of age or older in cancer clinical trials
-
DOI 10.1200/JCO.2003.08.010
-
Lewis JH, Kilgore ML, Goldman DP, et al: Participation of patients 65 years of age or older in cancer clinical trials. J Clin Oncol 21:1383-1389, 2003 (Pubitemid 46606420)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.7
, pp. 1383-1389
-
-
Lewis, J.H.1
Kilgore, M.L.2
Goldman, D.P.3
Trimble, E.L.4
Kaplan, R.5
Montello, M.J.6
Housman, M.G.7
Escarce, J.J.8
-
5
-
-
16544371710
-
Enrollment of elderly patients in clinical trials for cancer drug registration: A 7-year experience by the US Food and Drug Administration
-
DOI 10.1200/JCO.2004.02.175
-
Talarico L, Chen G, Pazdur R: Enrollment of elderly patients in clinical trials for cancer registration: A 7-year experience by the US Food and Drug Administration. J Clin Oncol 22:4626-4631, 2004 (Pubitemid 41185131)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.22
, pp. 4626-4631
-
-
Talarico, L.1
Chen, G.2
Pazdur, R.3
-
6
-
-
0342547065
-
The effects of diet, aging and disease-states on presystemic elimination and oral drug bioavailability in humans
-
DOI 10.1016/S0169-409X(97)00040-9, PII S0169409X97000409
-
Wilkinson GR: The effects of diet, aging and disease-states on presystemic elimination and oral drug bioavailability in humans. Adv Drug Deliv Rev 27:129-159, 1997 (Pubitemid 27417870)
-
(1997)
Advanced Drug Delivery Reviews
, vol.27
, Issue.2-3
, pp. 129-159
-
-
Wilkinson, G.R.1
-
7
-
-
84864712711
-
Analgesics in patients with hepatic impairment: Pharmacology and clinical implications
-
Bosilkovska M, Walder B, Besson M: Analgesics in patients with hepatic impairment: Pharmacology and clinical implications. Drugs 72:1645-1649, 2012
-
(2012)
Drugs
, vol.72
, pp. 1645-1649
-
-
Bosilkovska, M.1
Walder, B.2
Besson, M.3
-
8
-
-
0035695389
-
Liver function and phase I drug metabolism in the elderly: A paradox
-
Schmucker DL: Liver function and phase I drug metabolism in the elderly: A paradox. Drugs Aging 18:837-851, 2001 (Pubitemid 34073129)
-
(2001)
Drugs and Aging
, vol.18
, Issue.11
, pp. 837-851
-
-
Schmucker, D.L.1
-
9
-
-
0027217141
-
Aging and the response to inhibition and induction of theophylline metabolism
-
Vestal RE, Cusack BJ, Crowley JJ, et al: Aging and the response to inhibition and induction of theophylline metabolism. Exp Gerontol 28:421-433, 1993 (Pubitemid 23226559)
-
(1993)
Experimental Gerontology
, vol.28
, Issue.4-5
, pp. 421-433
-
-
Vestal, R.E.1
Cusack, B.J.2
Crowley, J.J.3
Loi, C.-M.4
-
10
-
-
0032853391
-
Differential kinetics of phenytoin in elderly patients
-
DOI 10.2165/00002512-199915030-00006
-
Bachmann KA, Belloto RJ Jr: Differential kinetics of phenytoin in elderly patients. Drugs Aging 15:235-250, 1999 (Pubitemid 29438142)
-
(1999)
Drugs and Aging
, vol.15
, Issue.3
, pp. 235-250
-
-
Bachmann, K.A.1
Belloto Jr., R.J.2
-
11
-
-
34250686532
-
The current state of knowledge on age, sex, and their interactions on clinical pharmacology
-
DOI 10.1038/sj.clpt.6100226, PII 6100226
-
Schwartz JB: The current state of knowledge on age, sex, and their interactions on clinical pharmacology. Clin Pharmacol Ther 82:87-96, 2007 (Pubitemid 46944201)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.82
, Issue.1
, pp. 87-96
-
-
Schwartz, J.B.1
-
12
-
-
70149103802
-
Pharmacokinetics and drug metabolism in the elderly
-
Klotz U: Pharmacokinetics and drug metabolism in the elderly. Drug Metab Rev 41:67-76, 2009
-
(2009)
Drug Metab Rev
, vol.41
, pp. 67-76
-
-
Klotz, U.1
-
13
-
-
84897405323
-
The glomerular filtration rate estimated by new and old equations as a predictor of important outcomes in elderly patients
-
Van Pottelbergh G, Vaes B, Adriaensen W, et al: The glomerular filtration rate estimated by new and old equations as a predictor of important outcomes in elderly patients. BMC Med 12:27, 2014
-
(2014)
BMC Med
, vol.12
, pp. 27
-
-
Van Pottelbergh, G.1
Vaes, B.2
Adriaensen, W.3
-
14
-
-
84886112334
-
Performance of Cockcroft-Gault, MDRD, and CKDEPI in estimating prevalence of renal function and predicting survival in the oldest old
-
Willems JM, Vlasveld T, den Elzen WP, et al: Performance of Cockcroft-Gault, MDRD, and CKDEPI in estimating prevalence of renal function and predicting survival in the oldest old. BMC Geriatr 13:113, 2013
-
(2013)
BMC Geriatr
, vol.13
, pp. 113
-
-
Willems, J.M.1
Vlasveld, T.2
Den Elzen, W.P.3
-
15
-
-
39449112419
-
Estimating gfr using serum cystatin c alone and in combination with serum creatinine: A pooled analysis of 3,418 individuals with ckd
-
DOI 10.1053/j.ajkd.2007.11.018, PII S0272638607015946
-
Stevens LA, Coresh J, Schmid CH, et al: Estimating GFR using serum cystatin C alone and in combination with serum creatinine: A pooled analysis of 3,418 individuals with CKD. Am J Kidney Dis 51:395-406, 2008 (Pubitemid 351273480)
-
(2008)
American Journal of Kidney Diseases
, vol.51
, Issue.3
, pp. 395-406
-
-
Stevens, L.A.1
Coresh, J.2
Schmid, C.H.3
Feldman, H.I.4
Froissart, M.5
Kusek, J.6
Rossert, J.7
Van Lente, F.8
Bruce III, R.D.9
Zhang, Y.L.10
Greene, T.11
Levey, A.S.12
-
16
-
-
77955551055
-
American Society of Clinical Oncology clinical practice guideline: Update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer
-
Burstein HJ, Prestrud AA, Seidenfeld J, et al: American Society of Clinical Oncology clinical practice guideline: Update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer. J Clin Oncol 28:3784-3796, 2010
-
(2010)
J Clin Oncol
, vol.28
, pp. 3784-3796
-
-
Burstein, H.J.1
Prestrud, A.A.2
Seidenfeld, J.3
-
17
-
-
42949164467
-
Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: The BIG 1-98 trial
-
Crivellari D, Sun Z, Coates AS, et al: Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: The BIG 1-98 trial. J Clin Oncol 26:1972-1979, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 1972-1979
-
-
Crivellari, D.1
Sun, Z.2
Coates, A.S.3
-
18
-
-
79955480679
-
Activity levels of tamoxifen metabolites at the estrogen receptor and the impact of genetic polymorphisms of phase I and II enzymes on their concentration levels in plasma
-
Mürdter TE, Schroth W, Bacchus-Gerybadze L, et al: Activity levels of tamoxifen metabolites at the estrogen receptor and the impact of genetic polymorphisms of phase I and II enzymes on their concentration levels in plasma. Clin Pharmacol Ther 89:708-717, 2001
-
(2001)
Clin Pharmacol Ther
, vol.89
, pp. 708-717
-
-
Mürdter, T.E.1
Schroth, W.2
Bacchus-Gerybadze, L.3
-
19
-
-
62449153701
-
The tamoxifen metabolite, endoxifen, is a potent antiestrogen that targets estrogen receptor alpha for degradation in breast cancer cells
-
Wu X, Hawse JR, Subramaniam M, et al: The tamoxifen metabolite, endoxifen, is a potent antiestrogen that targets estrogen receptor alpha for degradation in breast cancer cells. Cancer Res 69:1722-1727, 2009
-
(2009)
Cancer Res
, vol.69
, pp. 1722-1727
-
-
Wu, X.1
Hawse, J.R.2
Subramaniam, M.3
-
20
-
-
4243063941
-
Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: Prominent roles for CYP3A and CYP2D6
-
DOI 10.1124/jpet.104.065607
-
Desta Z, Ward BA, Soukhova NV, et al: Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: Prominent roles for CYP3A and CYP2D6. J Pharmacol Exp Ther 310:1062-1075, 2004 (Pubitemid 39108928)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.310
, Issue.3
, pp. 1062-1075
-
-
Desta, Z.1
Ward, B.A.2
Soukhova, N.V.3
Flockhart, D.A.4
-
21
-
-
0036124107
-
CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
-
DOI 10.1517/14622416.3.2.229
-
Bradford LD: CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 3:229-243, 2002 (Pubitemid 34223859)
-
(2002)
Pharmacogenomics
, vol.3
, Issue.2
, pp. 229-243
-
-
Bradford, L.D.1
-
22
-
-
77954907009
-
Coprescription of tamoxifen and medications that inhibit CYP2D6
-
Sideras K, Ingle JN, Ames MM, et al: Coprescription of tamoxifen and medications that inhibit CYP2D6. J Clin Oncol 28:2768-2776, 2010
-
(2010)
J Clin Oncol
, vol.28
, pp. 2768-2776
-
-
Sideras, K.1
Ingle, J.N.2
Ames, M.M.3
-
23
-
-
33745347897
-
Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: Implication for optimization of breast cancer treatment
-
DOI 10.1016/j.clpt.2006.03.013, PII S0009923606001366
-
Borges S, Desta Z, Li L, et al: Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: Implications for optimization of breast cancer treatment. Clin Pharmacol Ther 80:61-74, 2006 (Pubitemid 43946844)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.80
, Issue.1
, pp. 61-74
-
-
Borges, S.1
Desta, Z.2
Li, L.3
Skaar, T.C.4
Ward, B.A.5
Nguyen, A.6
Jin, Y.7
Storniolo, A.M.8
Nikoloff, D.M.9
Wu, L.10
Hillman, G.11
Hayes, D.F.12
Stearns, V.13
Flockhart, D.A.14
-
24
-
-
19944434201
-
CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
-
Jin Y, Desta Z, Sterns V, et al: CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J Natl Cancer Inst 97:30-39, 2005
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 30-39
-
-
Jin, Y.1
Desta, Z.2
Sterns, V.3
-
25
-
-
0034015751
-
Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: Prediction of in vivo drug interactions
-
DOI 10.1046/j.1365-2125.2000.00134.x
-
Ohyama K, Nakajima M, Suzuki M, et al: Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: Prediction of in vivo drug interactions. Br J Clin Pharmacol 49:244-253, 2000 (Pubitemid 30150986)
-
(2000)
British Journal of Clinical Pharmacology
, vol.49
, Issue.3
, pp. 244-253
-
-
Ohyama, K.1
Nakajima, M.2
Suzuki, M.3
Shimada, N.4
Yamazaki, H.5
Yokoi, T.6
-
27
-
-
70349929431
-
Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen
-
Schroth W, Goetz MP, Hamann U, et al: Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen. JAMA 302:1429-1436, 2009
-
(2009)
JAMA
, vol.302
, pp. 1429-1436
-
-
Schroth, W.1
Goetz, M.P.2
Hamann, U.3
-
28
-
-
84893732936
-
CYP2D6 genotype and adjuvant tamoxifen: Metaanalysis of heterogeneous study populations
-
Province MA, Goetz MP, Brauch H, et al: CYP2D6 genotype and adjuvant tamoxifen: Metaanalysis of heterogeneous study populations. Clin Pharmacol Ther 95:216-227, 2014
-
(2014)
Clin Pharmacol Ther
, vol.95
, pp. 216-227
-
-
Province, M.A.1
Goetz, M.P.2
Brauch, H.3
-
29
-
-
84885324195
-
Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment
-
Lien EA, Søiland H, Lundgren S, et al: Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment. Breast Cancer Res Treat 141:243-248, 2013
-
(2013)
Breast Cancer Res Treat
, vol.141
, pp. 243-248
-
-
Lien, E.A.1
Søiland, H.2
Lundgren, S.3
-
30
-
-
28444498289
-
Excretion of hydroxylated metabolites of tamoxifen in human bile and urine
-
Kisanga ER, Mellgren G, Lien EA: Excretion of hydroxylated metabolites of tamoxifen in human bile and urine. Anticancer Res 25:4487-4492, 2005 (Pubitemid 41729501)
-
(2005)
Anticancer Research
, vol.25
, pp. 4487-4492
-
-
Kisanga, E.R.1
Mellgren, G.2
Lien, E.A.3
-
31
-
-
67650932092
-
Effects of CYP2D6 genotypes on age-related change of flecainide metabolism: Involvement of CYP1A2-mediated metabolism
-
Doki K, Homma M, Kuga K, et al: Effects of CYP2D6 genotypes on age-related change of flecainide metabolism: Involvement of CYP1A2-mediated metabolism. Br J Clin Pharmacol 68:89-96, 2009
-
(2009)
Br J Clin Pharmacol
, vol.68
, pp. 89-96
-
-
Doki, K.1
Homma, M.2
Kuga, K.3
-
32
-
-
0028036727
-
Selective biotransformation of taxol to 6 alphahydroxytaxol by human cytochrome P450 2C8
-
Rahman A, Korzekwa KR, Grogan J, et al: Selective biotransformation of taxol to 6 alphahydroxytaxol by human cytochrome P450 2C8. Cancer Res 54:5543-5546, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 5543-5546
-
-
Rahman, A.1
Korzekwa, K.R.2
Grogan, J.3
-
33
-
-
0037219633
-
Altered clearance of unbound paclitaxel in elderly patients with metastatic breast cancer
-
DOI 10.1016/S0959-8049(02)00611-1, PII S0959804902006111
-
Smorenburg CH, ten Tije AJ, Verweij J, et al: Altered clearance of unbound paclitaxel in elderly patients with metastatic breast cancer. Eur J Cancer 39:196-202, 2003 (Pubitemid 36057070)
-
(2003)
European Journal of Cancer
, vol.39
, Issue.2
, pp. 196-202
-
-
Smorenburg, C.H.1
Ten Tije, A.J.2
Verweij, J.3
Bontenbal, M.4
Mross, K.5
Van Zomeren, D.M.6
Seynaeve, C.7
Sparreboom, A.8
-
34
-
-
33646366957
-
Prospective evaluation of the relationship of patient age and paclitaxel clinical pharmacology: Cancer and Leukemia Group B (CALGB 9762)
-
DOI 10.1200/JCO.2005.03.9289
-
Lichtman SM, Hollis D, Miller AA, et al: Prospective evaluation of the relationship of patient age and paclitaxel clinical pharmacology: Cancer and Leukemia Group B (CALGB 9762). J Clin Oncol 24:1846-1851, 2006 (Pubitemid 46638982)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.12
, pp. 1846-1851
-
-
Lichtman, S.M.1
Hollis, D.2
Miller, A.A.3
Rosner, G.L.4
Rhoades, C.A.5
Lester, E.P.6
Millard, F.7
Byrd, J.8
Cullinan, S.A.9
Rosen, D.M.10
Parise, R.A.11
Ratain, M.J.12
Egorin, M.J.13
-
35
-
-
27644562207
-
Association of paclitaxel pharmacokinetics with the development of peripheral neuropathy in patients with advanced cancer
-
DOI 10.1158/1078-0432.CCR-05-0298
-
Mielke S, Sparreboom A, Steinberg SM, et al: Association of paclitaxel pharmacokinetics with the development of peripheral neuropathy in patients with advanced cancer. Clin Cancer Res 11:4843-4850, 2005 (Pubitemid 41557204)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.13
, pp. 4843-4850
-
-
Mielke, S.1
Sparreboom, A.2
Steinberg, S.M.3
Gelderblom, H.4
Unger, C.5
Behringer, D.6
Mross, K.7
-
36
-
-
0037080432
-
Comparative pharmacokinetics of unbound paclitaxel during 1- and 3-hour infusions
-
DOI 10.1200/JCO.20.2.574
-
Gelderblom H, Mross K, ten Tije AJ, et al: Comparative pharmacokinetics of unbound paclitaxel during 1- and 3-hour infusions. J Clin Oncol 20:574-581, 2002 (Pubitemid 34072542)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.2
, pp. 574-581
-
-
Gelderblom, H.1
Mross, K.2
Ten Tije, A.J.3
Behringer, D.4
Mielke, S.5
Van Zomeren, D.M.6
Verweij, J.7
Sparreboom, A.8
-
37
-
-
77951971581
-
Randomized phase II trial of weekly paclitaxel combined with carboplatin versus standard paclitaxel combined with carboplatin for elderly patients with advanced non-small-cell lung cancer
-
Sakakibara T, Inoue A, Sugawara S, et al: Randomized phase II trial of weekly paclitaxel combined with carboplatin versus standard paclitaxel combined with carboplatin for elderly patients with advanced non-small-cell lung cancer. Ann Oncol 21:795-799, 2010
-
(2010)
Ann Oncol
, vol.21
, pp. 795-799
-
-
Sakakibara, T.1
Inoue, A.2
Sugawara, S.3
-
38
-
-
33645736326
-
Peripheral neuropathy induced by microtubule-stabilizing agents
-
DOI 10.1200/JCO.2005.04.0543
-
Lee JJ, Swain SM: Peripheral neuropathy induced by microtubule- stabilizing agents. J Clin Oncol 24:1633-1642, 2006 (Pubitemid 46638788)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.10
, pp. 1633-1642
-
-
Lee, J.J.1
Swain, S.M.2
-
39
-
-
0029970249
-
The impact of diabetes mellitus on the toxicity of therapy for advanced ovarian cancer
-
DOI 10.1006/gyno.1996.0090
-
Gogas H, Shapiro F, Aghajanian C, et al: The impact of diabetes mellitus on the toxicity of therapy for advanced ovarian cancer. Gynecol Oncol 61:22-26, 1996 (Pubitemid 26108524)
-
(1996)
Gynecologic Oncology
, vol.61
, Issue.1
, pp. 22-26
-
-
Gogas, H.1
Shapiro, F.2
Aghajanian, C.3
Fennelly, D.4
Almadrones, L.5
Hoskins, W.J.6
Spriggs, D.R.7
-
40
-
-
84875940168
-
CYP2C83 increases risk of neuropathy in breast cancer patients treated with paclitaxel
-
Hertz DL, Roy S, Motsinger-Reif AA, et al: CYP2C8*3 increases risk of neuropathy in breast cancer patients treated with paclitaxel. Ann Oncol 24:1472-1478, 2013
-
(2013)
Ann Oncol
, vol.24
, pp. 1472-1478
-
-
Hertz, D.L.1
Roy, S.2
Motsinger-Reif, A.A.3
-
41
-
-
79953052657
-
Polymorphisms in cytochromes P450 2C8 and 3A4 are associated with paclitaxel neurotoxicity
-
Leskelä S, Jara C, Leandro-García LJ, et al: Polymorphisms in cytochromes P450 2C8 and 3A4 are associated with paclitaxel neurotoxicity. Pharmacogenomics J 11:121-129, 2011
-
(2011)
Pharmacogenomics J
, vol.11
, pp. 121-129
-
-
Leskelä, S.1
Jara, C.2
Leandro-García, L.J.3
-
42
-
-
0034791777
-
Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
-
DOI 10.1097/00008571-200110000-00006
-
Dai D, Zeldin DC, Blaisdell JA, et al: Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics 11:597-607, 2001 (Pubitemid 32953585)
-
(2001)
Pharmacogenetics
, vol.11
, Issue.7
, pp. 597-607
-
-
Dai, D.1
Zeldin, D.C.2
Blaisdell, J.A.3
Chanas, B.4
Coulter, S.J.5
Ghanayem, B.I.6
Goldstein, J.A.7
-
43
-
-
34548081331
-
Pharmacogenetic analysis of paclitaxel transport and metabolism genes in breast cancer
-
DOI 10.1038/sj.tpj.6500434, PII 6500434
-
Marsh S, Somlo G, Li X, et al: Pharmacogenetic analysis of paclitaxel transport and metabolism genes in breast cancer. Pharmacogenomics J 7:362-365, 2007 (Pubitemid 47484774)
-
(2007)
Pharmacogenomics Journal
, vol.7
, Issue.5
, pp. 362-365
-
-
Marsh, S.1
Somlo, G.2
Li, X.3
Frankel, P.4
King, C.R.5
Shannon, W.D.6
McLeod, H.L.7
Synold, T.W.8
-
44
-
-
77952313395
-
Human liver expression of CYP2C8: Gender, age, and genotype effects
-
Naraharisetti SB, Lin YS, Rieder MJ, et al: Human liver expression of CYP2C8: Gender, age, and genotype effects. Drug Metab Dispos 38:889-893, 2010
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 889-893
-
-
Naraharisetti, S.B.1
Lin, Y.S.2
Rieder, M.J.3
-
45
-
-
33751044628
-
Association of ABCB1 genotypes with paclitaxel-mediated peripheral neuropathy and neutropenia
-
DOI 10.1016/j.ejca.2006.06.017, PII S0959804906006009
-
Sissung TM, Mross K, Steinberg SM, et al: Association of ABCB1 genotypes with paclitaxelmediated peripheral neuropathy and neutropenia. Eur J Cancer 42:2893-2896, 2006 (Pubitemid 44755257)
-
(2006)
European Journal of Cancer
, vol.42
, Issue.17
, pp. 2893-2896
-
-
Sissung, T.M.1
Mross, K.2
Steinberg, S.M.3
Behringer, D.4
Figg, W.D.5
Sparreboom, A.6
Mielke, S.7
-
46
-
-
35648997048
-
Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: The scottish randomised trial in ovarian cancer
-
DOI 10.1200/JCO.2006.10.4752
-
Marsh S, Paul J, King CR, et al: Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: The Scottish Randomised Trial in Ovarian Cancer. J Clin Oncol 25:4528-4535, 2007 (Pubitemid 350035308)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.29
, pp. 4528-4535
-
-
Marsh, S.1
Paul, J.2
King, C.R.3
Gifford, G.4
McLeod, H.L.5
Brown, R.6
-
47
-
-
56749182291
-
Prevalence of undertreatment in cancer pain: A review of published literature
-
Deandrea S, Montanari M, Moja L, et al: Prevalence of undertreatment in cancer pain: A review of published literature. Ann Oncol 19:1985-1991, 2008
-
(2008)
Ann Oncol
, vol.19
, pp. 1985-1991
-
-
Deandrea, S.1
Montanari, M.2
Moja, L.3
-
48
-
-
84863951751
-
Opioid prescription after pain assessment: A populationbased cohort of elderly patients with cancer
-
Barbera L, Seow H, Husain A, et al: Opioid prescription after pain assessment: A populationbased cohort of elderly patients with cancer. J Clin Oncol 30:1095-1099, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 1095-1099
-
-
Barbera, L.1
Seow, H.2
Husain, A.3
-
50
-
-
7044245703
-
Opioids in renal failure and dialysis patients
-
DOI 10.1016/j.jpainsymman.2004.02.021, PII S0885392404003355
-
Dean M: Opioids in renal failure and dialysis patients. J Pain Symptom Manage 28:497-504, 2004 (Pubitemid 39422488)
-
(2004)
Journal of Pain and Symptom Management
, vol.28
, Issue.5
, pp. 497-504
-
-
Dean, M.1
-
51
-
-
84855968708
-
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype
-
Crews KR, Gaedigk A, Dunnenberger HM, et al: Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype. Clin Pharmacol Ther 91:321-326, 2012
-
(2012)
Clin Pharmacol Ther
, vol.91
, pp. 321-326
-
-
Crews, K.R.1
Gaedigk, A.2
Dunnenberger, H.M.3
-
52
-
-
0028836343
-
Affinity profiles of morphine, codeine, dihydrocodeine and their glucuronides at opioid receptor subtypes
-
Mignat C, Wille U, and Ziegler A: Affinity profiles of morphine, codeine, dihydrocodeine and their glucuronides at opioid receptor subtypes. Life Sci 56:793-799, 1995
-
(1995)
Life Sci
, vol.56
, pp. 793-799
-
-
Mignat, C.1
Wille, U.2
Ziegler, A.3
-
53
-
-
0026669218
-
The analgesic activity of morphine-6-glucuronide
-
Osborne R, Thompson P, Joel S, et al: The analgesic activity of morphine-6-glucuronide. Br J Clin Pharmacol 34:130-138, 1992
-
(1992)
Br J Clin Pharmacol
, vol.34
, pp. 130-138
-
-
Osborne, R.1
Thompson, P.2
Joel, S.3
-
54
-
-
34547644659
-
Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication
-
DOI 10.1038/sj.tpj.6500406, PII 6500406
-
Kirchheiner J, Schmidt H, Tzvetkov M, et al: Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication. Pharmacogenomics J 7:257-265, 2007 (Pubitemid 47202488)
-
(2007)
Pharmacogenomics Journal
, vol.7
, Issue.4
, pp. 257-265
-
-
Kirchheiner, J.1
Schmidt, H.2
Tzvetkov, M.3
Keulen, J.-T.4
Lotsch, J.5
Roots, I.6
Brockmoller, J.7
-
55
-
-
69049096090
-
Codeine ultrarapid-metabolism genotype, and postoperative death
-
Ciszkowski C, Madadi P, Phillips MS, et al: Codeine ultrarapid-metabolism genotype, and postoperative death. N Engl J Med 361:827-828, 2009
-
(2009)
N Engl J Med
, vol.361
, pp. 827-828
-
-
Ciszkowski, C.1
Madadi, P.2
Phillips, M.S.3
-
56
-
-
11144221180
-
Codeine intoxication associated with ultrarapid CYP2D6 metabolism
-
DOI 10.1056/NEJMoa041888
-
Gasche Y, Daali Y, Fathi M, et al: Codeine intoxication associated with ultrarapid CYP2D6 metabolism. N Engl J Med 351:2827-2831, 2004 (Pubitemid 40051906)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.27
, pp. 2827-2831
-
-
Gasche, Y.1
Daali, Y.2
Fathi, M.3
Chiappe, A.4
Cottini, S.5
Dayer, P.6
Desmeules, J.7
-
58
-
-
14844303761
-
Capecitabine: A review
-
DOI 10.1016/j.clinthera.2005.01.005
-
Walko CM, Lindley C: Capecitabine: A review. Clin Ther 27:23-44, 2005 (Pubitemid 40347299)
-
(2005)
Clinical Therapeutics
, vol.27
, Issue.1
, pp. 23-44
-
-
Walko, C.M.1
Lindley, C.2
-
59
-
-
0033783056
-
Mechanism of action of fluoropyrimidines: Relevance to the new developments in colorectal cancer chemotherapy
-
Sobrero A, Guglielmi A, Grossi F, et al: Mechanism of action of fluoropyrimidines: Relevance to the new developments in colorectal cancer chemotherapy. Semin Oncol 27:72-77, 2000
-
(2000)
Semin Oncol
, vol.27
, pp. 72-77
-
-
Sobrero, A.1
Guglielmi, A.2
Grossi, F.3
-
60
-
-
2942648695
-
Four decades of continuing innovation with fluorouracil: Current and future approaches to fluorouracil chemoradiation therapy
-
DOI 10.1200/JCO.2004.08.009
-
Rich TA, Shepard RC, Mosley ST: Four decades of continuing innovation with fluorouracil: Current and future approaches to fluorouracil chemoradiation therapy. J Clin Oncol 22:2214-2232, 2004 (Pubitemid 41095158)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.11
, pp. 2214-2232
-
-
Rich, T.A.1
Shepard, R.C.2
Mosley, S.T.3
-
61
-
-
0037144354
-
Increased risk of grade IV neutropenia after administration of 5-fluorouracil due to a dihydropyrimidine dehydrogenase deficiency: High prevalence of the IVS14+1G>A mutation
-
DOI 10.1002/ijc.10599
-
Van Kuilenburg AB, Meinsma R, Zoetekouw L, et al: Increased risk of grade IV neutropenia after administration of 5-fluorouracil due to a dihydropyrimidine dehydrogenase deficiency: High prevalence of the IVS14+1g>a mutation. Int J Cancer 101:253-258, 2002 (Pubitemid 34970893)
-
(2002)
International Journal of Cancer
, vol.101
, Issue.3
, pp. 253-258
-
-
Van Kuilenburg, A.B.P.1
Meinsma, R.2
Zoetekouw, L.3
Van Gennip, A.H.4
-
62
-
-
33947588763
-
Should DPD analysis be required prior to prescribing fluoropyrimidines?
-
DOI 10.1016/j.ejca.2007.01.030, PII S0959804907000950
-
Yen JL, McLeod HL: Should DPD analysis be required prior to prescribing fluoropyrimidines? Eur J Cancer 43:1011-1016, 2007 (Pubitemid 46483039)
-
(2007)
European Journal of Cancer
, vol.43
, Issue.6
, pp. 1011-1016
-
-
Yen, J.L.1
McLeod, H.L.2
-
63
-
-
0026636184
-
Influence of sex and age on fluorouracil clearance
-
Milano G, Etienne MC, Cassuto-Viguier E, et al: Influence of sex and age on fluorouracil clearance. J Clin Oncol 10:1171-1175, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 1171-1175
-
-
Milano, G.1
Etienne, M.C.2
Cassuto-Viguier, E.3
-
64
-
-
0031901763
-
Long-term weekly treatment of colorectal metastatic cancer with fluorouracil and leucovorin: Results of a multicentric prospective trial of fluorouracil dosage optimization by pharmacokinetic monitoring in 152 patients
-
Gamelin E, Boisdron-Celle M, Delva R, et al: Long-term weekly treatment of colorectal metastatic cancer with fluorouracil and leucovorin: Results of a multicentric prospective trial of fluorouracil dosage optimization by pharmacokinetic monitoring in 152 patients. J Clin Oncol 16:1470-1478, 1998 (Pubitemid 28175768)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.4
, pp. 1470-1478
-
-
Gamelin, E.1
Boisdron-Celle, M.2
Delva, R.3
Regimbeau, C.4
Cailleux, P.E.5
Alleaume, C.6
Maillet, M.L.7
Goudier, M.J.8
Sire, M.9
Person-Joly, M.C.10
Maigre, M.11
Maillart, P.12
Fety, R.13
Burtin, P.14
Lortholary, A.15
Dumesnil, Y.16
Picon, L.17
Geslin, J.18
Gesta, P.19
Danquechin-Dorval, E.20
Larra, F.21
Robert, J.22
more..
-
65
-
-
72949086481
-
Pharmacokinetically guided dose adjustment of 5-fluorouracil: A rational approach to improving therapeutic outcomes
-
Saif MW, Choma A, Salamone SJ, et al: Pharmacokinetically guided dose adjustment of 5-fluorouracil: A rational approach to improving therapeutic outcomes. J Natl Cancer Inst 101:1543-1552, 2009
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1543-1552
-
-
Saif, M.W.1
Choma, A.2
Salamone, S.J.3
-
66
-
-
43749093441
-
Individual fluorouracil dose adjustment based on pharmacokinetic follow-up compared with conventional dosage: Results of a multicenter randomized trial of patients with metastatic colorectal cancer
-
Gamelin E, Delva R, Jacob J, et al: Individual fluorouracil dose adjustment based on pharmacokinetic follow-up compared with conventional dosage: Results of a multicenter randomized trial of patients with metastatic colorectal cancer. J Clin Oncol 26: 2099-2105, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 2099-2105
-
-
Gamelin, E.1
Delva, R.2
Jacob, J.3
|