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Volumn 27, Issue 5 SUPPL. 10, 2000, Pages 72-77

Mechanism of action of fluoropyrimidines: Relevance to the new developments in colorectal cancer chemotherapy

Author keywords

[No Author keywords available]

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE; CAPECITABINE; DOXIFLURIDINE; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; FLUOROURIDINE; FOLIC ACID ANTAGONIST; FOLINIC ACID; METHOTREXATE; THYMIDYLATE SYNTHASE INHIBITOR; TRIMETREXATE; UFT;

EID: 0033783056     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (46)

References (26)
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  • 3
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  • 11
  • 13
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    • Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules
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    • Aschele, C.1    Sobrero, A.2    Faderan, M.A.3
  • 15
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    • A prospectively randomized trial comparing 5FU bolus with low dose folinic acid (FUFOLld) and 5FU bolus plus continuous infusion with high dose folinic acid (LV5FU2) for advanced colorectal cancer
    • abstr 455
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 194
    • De Gramont, A.1    Bosset, J.F.2    Milan, C.3
  • 20
    • 0018899298 scopus 로고
    • Tissue distribution of 5'-deoxy-5-fluorouridine and deliver 5-fluorouracil in tumor bearing mice and rats
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    • Suzuky, S.1    Hongu, Y.2    Fukazawa, H.3
  • 23
    • 0028281781 scopus 로고
    • 5-Ethynyluracil (776C85): Modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma
    • (1994) Cancer Res , vol.54 , pp. 1507-1510
    • Cao, S.1    Rustum, Y.M.2    Spector, T.3
  • 24
    • 10544243363 scopus 로고    scopus 로고
    • Pharmacokinetic, oral bioavailability and safety study of 5-fluorouracil in patients treated with 776C85, an inactivator of dihydropyrimidine dehydrogenase
    • (1996) J Clin Oncol , vol.14 , pp. 3085-3096
    • Baker, S.D.1    Khor, S.P.2    Adjei, A.A.3
  • 25
    • 0028099423 scopus 로고
    • Phase II trial of uracil and tegafur plus oral leucovorin: An effective oral regimen in the treatment of metastatic colorectal cancer
    • (1994) J Clin Oncol , vol.12 , pp. 2296-2300
    • Pazdur, R.1    Lassere, Y.2    Rhodes, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.