Soluble biglycan induces the production of ICAM-1 and MCP-1 in human aortic valve interstitial cells through TLR2/4 and the ERK1/2 pathway

Inflammation Research

Volumn 63, Issue 9, 2014, Pages 703-710

  Song, Rui ^a,b   Ao, Lihua ^a   Zhao, Ke Seng ^b   Zheng, Daniel ^a   Venardos, Neil ^a   Fullerton, David A ^a   Meng, Xianzhong ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

AVIC; Biglycan; Cytokines; TLR2; TLR4

Indexed keywords

BIGLYCAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; CCL2 PROTEIN, HUMAN; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

AORTA VALVE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INFLAMMATION; LEYDIG CELL; MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; SOLUBILITY;

AORTIC VALVE; BIGLYCAN; CELLS, CULTURED; CHEMOKINE CCL2; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MAP KINASE SIGNALING SYSTEM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA, SMALL INTERFERING; SOLUBILITY; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 84906266470     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-014-0743-3     Document Type: Article

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