Mechanical Strain and the Aortic Valve: Influence on Fibroblasts, Extracellular Matrix, and Potential Stenosis

Annals of Thoracic Surgery

Volumn 88, Issue 5, 2009, Pages 1476-1483

  Lehmann, Sven ^a   Walther, Thomas ^a   Kempfert, Jörg ^a   Rastan, Ardawan ^a   Garbade, Jens ^a   Dhein, Stefan ^a   Mohr, Friedrich W ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYETHYL METHACRYLATE; ALKALINE PHOSPHATASE; BIGLYCAN; DECORIN; OSTEOCALCIN; OSTEOPONTIN; SCLEROPROTEIN; TENASCIN;

AGED; AORTA STENOSIS; AORTA VALVE; AORTA VALVE REPLACEMENT; ARTICLE; CALCIFICATION; CELL POPULATION; CLINICAL ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; FIBROBLAST; HUMAN; HUMAN TISSUE; IMMUNOHISTOLOGY; LEYDIG CELL; MALE; MOLECULAR MECHANICS; PRESSURE GRADIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; WESTERN BLOTTING; AORTA VALVE STENOSIS; BIOSYNTHESIS; CELL CULTURE; IN VITRO STUDY; MECHANICAL STRESS; METABOLISM; PATHOLOGY; PHYSIOLOGY;

AGED; AORTIC VALVE; AORTIC VALVE STENOSIS; CELLS, CULTURED; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FEMALE; FIBROBLASTS; HUMANS; MALE; STRESS, MECHANICAL;

EID: 70449701957     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2009.07.025     Document Type: Article

References (31)

1. Lehmann S., Walther T., Kempfert J., et al. Stentless versus conventional xenograft aortic valve replacement: Midterm results of a prospectively randomized trial. Ann Thorac Surg 84 (2007) 467-472
2. Ross J., and Braunwald E. Aortic stenosis. Circulation 381 Suppl (1968) 61-67
3. Latif N., Sarathchandra P., Taylor P.M., Antoniw J., and Yacoub M.H. Localisation and pattern of extracellular matrix components in human heart valves. J Heart Valve Dis 14 (2005) 218-227
4. Baig M., Daicoff G., and Ayoub E. Comparative studies of the acid mucopolysaccharide composition of rheumatic and normal heart valves in man. Circ Res 42 (1978) 271-275
5. Murata K. Acidic glycosaminoglycans in human heart valves. J Mol Cell Cardiol 13 (1981) 281-292
6. Merryman W.D., Youn I., Lukoff H.D., et al. Correlation between heart valve interstitial cell stiffness and transvalvular pressure: implications for collagen biosynthesis. Am J Physiol 290 (2006) H224-H231
7. Balachandran K., Konduri S., Sucosky P., Jo H., and Yoganathan A.P. An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch. Ann Biomed Eng 34 (2006) 1655-1665
8. Torii S., Bashey R., and Nakao K. Acid mucopolysaccaride composition of human-heart valve. Biochim Biophys Acta 101 (1965) 285-291
9. Laurent C., Laurent U.B., and Fraser J.R. The structure and function of hyaluronan: an overview. Immunol Cell Biol 74 (1996) A1-A7
10. Quinn T.M., Dierickx P., and Grodzinsky A.J. Glycosaminoglycan network geometry may contribute to anisotropic hydraulic permeability in cartilage under compression. J Biomech 34 (2001) 1483-1490
11. Engfeldt B., and Hjerpe A. Glycosaminoglycans and proteoglycans of human bone tissue at different stages of mineralization. Acta Pathol Microbiol Scand A 84 (1976) 95-106
12. Hunter G.K. Role of proteoglycan in the provisional calcification of cartilage. A review and reinterpretation. Clin Orthop 262 (1991) 256-280
13. Mohler E.R., Gannon F., Reynolds C., Zimmerman R., Keane M.G., and Kaplan F.S. Bone formation and inflammation in cardiac valves. Circulation 103 (2001) 1522-1528
14. Poole A.R., Pidoux I., and Rosenberg L. Role of proteoglycans in endochondral ossification: immunofluorescent localization of link protein and proteoglycan monomer in bovine fetal epiphyseal growth plate. J Cell Biol 92 (1982) 249-260
15. Rajamannan N.M. Calcific aortic stenosis: a disease ready for prime time. Circulation 114 (2006) 2007-2009
16. Satta J., Melkko J., Pollanen R., et al. Progression of human aortic valve stenosis is associated with tenascin-C expression. J Am Coll Cardiol 39 (2002) 96-101
17. Simionescu D.T., Lovekamp J.J., and Vyavahare N.R. Degeneration of bioprosthetic heart valve cusp and wall tissues is initiated during tissue preparation: an ultrastructural study. J Heart Valve Dis 12 (2003) 226-234
18. Simionescu D.T., Lovekamp J.J., and Vyavahare N.R. Glycosaminoglycan-degrading enzymes in porcine aortic heart valves: implications for bioprosthetic heart valve degeneration. J Heart Valve Dis 12 (2003) 217-225
19. Garg V., Muth A.N., Ransom J.F., et al. Mutations in NOTCH1 cause aortic valve disease. Nature 437 (2005) 270-274
20. Gitler A.D., Lu M.M., Jiang Y.Q., Epstein J.A., and Gruber P.J. Molecular markers of cardiac endocardial cushion development. Dev Dyn 228 (2003) 643-650
21. Cripe L., Andelfinger G., Martin L.J., Shooner K., and Benson D.W. Bicuspid aortic valve is heritable. J Am Coll Cardiol 44 (2004) 138-143
22. Rodriguez M., Lindinger A., Perez Lustres J.L., et al. Femtosecond dynamics of proteoheparan sulfate (HS-PG) after UV excitation-a readout for arteriosclerotic nanoplaque formation?. Biochem Biophys Res Commun 345 (2006) 886-893
23. Siegel G., Malmsten M., Klussendorf D., and Michel F. A receptor-based biosensor for lipoprotein docking at the endothelial surface and vascular matrix. Biosens Bioelectron 16 (2001) 895-904
24. Olsson M., Dalsgaard C.J., Haegerstrand A., Rosenqvist M., Rydén L., and Nilsson J. Accumulation of T lymphocytes and expression of interleukin-2 receptors in nonrheumatic stenotic aortic valves. J Am Coll Cardiol 23 (1994) 1162
25. Otto C.M., Kuusisto J., Reichenbach D.D., Gown A.M., and O'Brien K.D. Characterization of the early lesion of "degenerative" valvular aortic stenosis: histological and immunohistochemical studies. Circulation 90 (1994) 844
26. Robicsek F., Thubrikar M.J., and Fokin A.A. Cause of degenerative disease of the trileaflet aortic valve: review of subject and presentation of a new theory. Ann Thorac Surg 73 (2002) 1346
27. Passik C.S., Ackermann D.M., Pluth J.R., and Edwards W.D. Temporal changes in the causes of aortic stenosis: a surgical pathologic study of 646 cases. Mayo Clin Proc 62 (1987) 119
28. Hultgren H.N. Osteitis deformans (Paget's disease) and calcific disease of the heart valves. Am J Cardiol 81 (1998) 1461
29. Maher E.R., Young G., Smyth-Walsh B., Pugh S., and Curtis J.R. Aortic and mitral valve calcification in patients with end-stage renal disease. Lancet 2 (1987) 875
30. Mohler E.R., Adam L.P., and McClelland P. Detection of osteopontin in calcified human aortic valves. Arterioscler Thromb Vasc Biol 17 (1997) 547
31. Hangaishi M., Taguchi J., Ikari Y., et al. Aortic valve stenosis in alkaptonuria: images in cardiovascular medicine. Circulation 98 (1998) 1148