The antiproliferative properties of the milk fat globule membrane are affected by extensive heating

Dairy Science and Technology

Volumn 94, Issue 5, 2014, Pages 439-453

  Zanabria, Romina ^a   Tellez, Angela M ^b   Griffiths, Mansel W ^a   Corredig, Milena ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b Richard Ivey School of Business   (Canada)

Author keywords

Antiproliferative; Bioactivity; Bioefficacy; MFGM; Milk heating

Indexed keywords

BIOACTIVITY; BIOSYNTHESIS; CELL CULTURE; CELL PROLIFERATION; OILS AND FATS; PHOSPHOLIPIDS; PROTEINS;

ANTI-PROLIFERATIVE; ANTIPROLIFERATIVE PROPERTIES; BIOEFFICACY; MFGM; MORPHOLOGICAL FEATURES; PROCESSING FUNCTIONALITY; PROTEIN-PROTEIN INTERACTIONS; SUPRAMOLECULAR STRUCTURE;

HEATING;

EID: 84906253829     PISSN: 19585586     EISSN: 19585594     Source Type: Journal    
DOI: 10.1007/s13594-014-0171-8     Document Type: Article

References (30)

1. Corredig, M. (1998). Properties of the milk fat globule membrane derived from buttermilks from different sources. Thesis. University of Guelph
2. Dalgleish DG, Banks JM (1991) The formation of complexes between serum-proteins and fat globules during heating of whole milk. Milchwissenschaft 46(2):75-78
3. Danthine S, Blecker C, Paquot M, Innocente N, Deroanne C (2000) Progress in milk fat globule membrane research: a review. Lait 80(2):209-222
4. Dommels YEM, Haring MMG, Keestra NGM, Alink GM, van Bladeren PJ, van Ommen B (2003) The role of cyclooxygenase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE (2) synthesis and cytotoxicity in human colorectal carcinoma cell lines. Carcinogenesis 24(3):385-392 (Pubitemid 36432632)
5. Estrada, R.; Stolowich, N.; & Yappert, M. C. (2008). Influence of temperature on P-31 NMR chemical shifts of phospholipids and their metabolites I. In chloroform-methanol-water. Anal. Biochem.; 380(1), 41-50.
6. Evers JM (2004) The milk fat globule membrane - compositional and structural changes post secretion by the mammary secretory cell. Int Dairy J 14(8):661-674 (Pubitemid 38791117)
7. Folch J, Lees M, Sloane Stanley H (1957) A Simple method for the Isolation and purification of total lipids from animal tissues. J, Biol Chem 226:497-509
8. Garcia C, Lutz NW, Confort-Gouny S, Cozzone PJ, Armand M, Bernard M (2012) Phospholipid fingerprints of milk from different mammalians determined by P-31 NMR: towards specific interest in human health. Food Chem 135(3):1777-1783
9. Guyomarc'h F, Law AJ, Dalgleish D (2003) Formation of soluble and micelle-bound protein aggregates in heated milk. J Agric Food Chem 51(16):4652-4660
10. Helmerich G, Koehler P (2003) Comparison of methods for the quantitative determination of phospholipids in lecithins and flour improvers. J Agr Food Chem 51(23):6645-6651
11. Hintze, K. J.; Snow, D.; Burtenshaw, I.; & Ward, R. E. (2011). Nutraceutical properties of milk fat globular membrane. In M. Elnashar (Ed.), Biotechnol. Biopolymers. (pp. 321-342) InTech. doi: 10.5772/683
12. Houlihan AV, Goddard PA, Kitchen BJ, Masters CJ (1992a) Changes in structure of the bovine-milk fat globule-membrane on heating whole milk. J Dairy Res 59(3):321-329
13. Houlihan AV, Goddard PA, Nottingham SM, Kitchen BJ, Masters CJ (1992b) Interactions between the bovine-milk fat globule-membrane and skim milk components on heating whole milk. J Dairy Res 59(2):187-195
14. Keenan TW, Patton S (1995) The milk fat globule membrane. In: Jensen RG (ed) Handbook of milk composition. Academic, San Diego, pp 5-50
15. Kim HHY, Jimenez Flores R (1995) Heat-induced interactions between the proteins of milk-fat globule-membrane and skim milk. J Dairy Sc 78(1):24-35
16. Larijani B, Poccia DL, Dickinson LC (2000) Phospholipid identification and quantification of membrane vesicle subfractions by P-31-H-1 two-dimensional nuclear magnetic resonance. Lipids 35(11):1289-1297 (Pubitemid 32005108)
17. Lee SJE, Sherbon JW (2002) Chemical changes in bovine milk fat globule membrane caused by heat treatment and homogenization of whole milk. J Dairy Res 69(4):555-567 (Pubitemid 35374583)
18. Mather IH (2000) A review and proposed nomenclature for major proteins of the milk-fat globule membrane. J Dairy Sci 83(2):203-247
19. McPherson AV (1984) Isolation and composition of milk fat globule membrane matrial I. From pasteurized milks and creams. J Dairy Res 51(2):279-287
20. Michalski MC, Januel C (2006) Does homogenization affect the human health properties of cow's milk? Trends Food Sci Tech 17(8):423-437 (Pubitemid 43833273)
21. Michalski MC, Michel F, Sainmont D, Briard V (2002) Apparent zeta-potential as a tool to assess mechanical damages to the milk fat globule membrane. Colloid Surface B 23(1):23-30 (Pubitemid 33111011)
22. Morin P, Jimenez-Flores R, Pouliot Y (2007) Effect of processing on the composition and microstructure of buttermilk and its milk fat globule membranes. Int Dairy J 17(10):1179-1187 (Pubitemid 47095285)
23. 31P NMR using a monophasic solvent mixture. Lipids 38(5):585-591 (Pubitemid 36760249)
24. Sanchez-Juanes F, Alonso JM, Zancada L, Hueso P (2009) Distribution and fatty acid content of phospholipids from bovine milk and bovine milk fat globule membranes. Int Dairy J 19(5):273-278
25. Sharma SK, Dalgleish DG (1994) Effect of heat-treatments on the incorporation of milk serum -proteins into the fat globule-membrane of homogenized milk. J Dairy Res 61(3):375-384
26. Simon KW, Roberts PC, Vespremi MJ, Manchen S, Schmelz EM (2009) Regulation of beta-catenin and connexin-43 expression: targets for sphingolipids in colon cancer prevention. Mol Nutr Food Res 53(3):332-340
27. Ye A, Singh H, Taylor MW, Anema S (2002) Characterization of protein components of natural and heat-treated milk fat globule membranes. Int Dairy J 12(4):393-402 (Pubitemid 34416025)
28. Ye AQ, Singh H, Oldfield DJ, Anema S (2004a) Kinetics of heat-induced association of beta-lactoglobulin and alpha-lactalbumin with milk fat globule membrane in whole milk. Int Dairy J 14(5):389-398 (Pubitemid 38345662)
29. Ye AQ, Singh H, Taylor MW, Anema S (2004b) Interactions of whey proteins with milk fat globule membrane proteins during heat treatment of whole milk. Lait 84(3):269-283 (Pubitemid 38732372)
30. Zanabria R, Tellez AM, Griffiths M, Corredig M (2013) Milk fat globule membrane isolate induces apoptosis in HT-29 human colon cancer cells. Food Func 4 2:222-30