Somatic cell mutations caused by 365 nm LED-UVA due to DNA double-strand breaks through oxidative damage

Photochemical and Photobiological Sciences

Volumn 13, Issue 9, 2014, Pages 1338-1346

  Fang, Xing ^a   Ide, Naohiro ^a   Higashi, Sho Ichi ^b   Kamei, Yasuhiro ^b   Toyooka, Tatsushi ^c   Ibuki, Yuko ^c   Kawai, Kazuaki ^d   Kasai, Hiroshi ^d   Okamoto, Keinosuke ^a   Arimoto Kobayashi, Sakae ^a   Negishi, Tomoe ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

^d UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; DROSOPHILA PROTEIN; HISTONE; MEIOTIC 41 PROTEIN, DROSOPHILA; MEIOTIC 9 PROTEIN, DROSOPHILA; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE;

ANIMAL; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DROSOPHILA MELANOGASTER; GENETICS; GROWTH, DEVELOPMENT AND AGING; LARVA; METABOLISM; MUTATION; OXIDATIVE STRESS; PHOSPHORYLATION; RADIATION RESPONSE; ULTRAVIOLET RADIATION;

ANIMALS; CELL CYCLE PROTEINS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HISTONES; LARVA; MUTATION; NUCLEAR PROTEINS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; ULTRAVIOLET RAYS;

EID: 84906230542     PISSN: 1474905X     EISSN: 14749092     Source Type: Journal    
DOI: 10.1039/c4pp00148f     Document Type: Article

References (54)

1. IARC, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. List of IARC Evaluations, WHO Press, Lyon, 2012, vol. 100
2. F. R. de Gruijl Photocarcinogenesis: UVA vs UVB Methods Enzymol. 2000 319 359 366
3. G. P. Pfeifer Y. H. You A. Besaratinia Mutations induced by ultraviolet light Mutat. Res. 2005 751 19 31
4. E. Sage P. M. Girard S. Francesconi Unravelling UVA-induced mutagenesis Photochem. Photobiol. Sci. 2012 11 74 80
5. A. Besaratinia S. I. Kim S. E. Bates G. P. Pfeifer Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C Proc. Natl. Acad. Sci. U. S. A. 2007 104 5953 5958
6. J. Cadet T. Douki J. L. Ravanat P. Di Mascio Sensitized formation of oxidatively generated damage to cellular DNA Photochem. Photobiol. Sci. 2009 8 903 911
7. E. Kvam R. M. Tyrrell Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation Carcinogenesis 1997 18 2379 2384
8. J. Cadet T. Douki S. Frelon S. Sauvaigo J. P. Pouget J. L. Ravanat Assessment of oxidative base damage to isolated and cellular DNA by HPLC-MS/MS measurement Free Radicals Biol. Med. 2002 33 441 449
9. P. J. Rochette J. P. Therrien R. Drouin D. Perdiz N. Bastien E. A. Drobetsky E. Sage UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine-thymine dipyrimidines and correlate with the mutation spectrum in rodent cells Nucleic Acids Res. 2003 31 2786 2794
10. S. Mouret C. Philippe J. Gracia-Chantegrei A. Banyasz S. Karpati D. Markovitsi T. Douki UVA-induced cyclobutane pyrimidine dimers in DNA: a direct photochemical mechanism? Org. Biomol. Chem. 2010 8 1760 1711
11. S. Mouret C. Baudouin M. Charveron A. Favier J. Cadet T. Douki Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation Proc. Natl. Acad. Sci. U. S. A. 2006 102 13765 13770
12. H. Ikehata K. Kawai J. Komura K. Sakatsume L. Wang M. Imai S. Higashi O. Nikaido K. Yamamoto K. Hieda M. Watanabe H. Kasai T. Ono UVA1 genotoxicity is mediated not by oxidative damage but by cyclobutane pyrimidine dimers in normal mouse skin J. Invest. Dermatol. 2008 128 2289 2296
13. T. Negishi C. Nagaoka H. Hayatsu K. Suzuki T. Hara M. Kubota M. Watanabe K. Hieda Somatic cell mutation induced by UVA and monochromatic UV radiation in repair-proficient and -deficient Drosophila melanogaster Photochem. Photobiol. 2001 73 493 498
14. M. Toyoshima S. Takinami K. Hieda Y. Furusawa T. Negishi The involvement of cell cycle checkpoint-mutations in the mutagenesis induced in Drosophila by a longer wavelength light band of solar UV Photochem. Photobiol. Sci. 2002 1 178 183
15. B. N. Ames R. Cathcart E. Schwiers P. Hochstein Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: A hypothesis Proc. Natl. Acad. Sci. U. S. A. 1981 78 6858 6862
16. A. J. Hilliker B. Duyf D. Evans J. P. Phillips Urate-null rosy mutants of Drosophila melanogaster are hypersensitive to oxygen stress Proc. Natl. Acad. Sci. U. S. A. 1992 89 4343 4347
17. B. F. Becker Towards the physiological function of uric acid Free Radicals Biol. Med. 1993 14 615 631
18. G. S. Scott D. C. Hooper The role of uric acid in protection against peroxynitrite-mediated pathology Med. Hypotheses 2001 56 95 100
19. N. Kuzkaya N. Weissmann D. G. Harrison S. Dikalov Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: Implications for uncoupling endothelial nitric oxide synthase Biochem. Pharmacol. 2005 70 343 354
20. N. Hayashi K. Togawa M. Yanagisawa J. Hosogi D. Mimura Y. Yamamoto Effect of sunlight exposure and aging on skin surface lipids and urate Exp. Dermatol. 2003 12 13 17
21. R. Kohen I. Gati Skin low molecular weight antioxidants and their role in aging and in oxidative stress Toxicology 2000 148 149 157
22. R. Arakawa M. Terao H. Hayashi H. Kasai T. Negishi Evaluation of oxidative damage induced by natural sunlight in Drosophila Genes Environ. 2006 28 153 159
23. Y. Hamatake A. Morita Y. Yuma K. Okamoto S. Arimoto T. Suzuki H. Kasai K. Kawai T. Negishi Hypersensitivity of a urate-null strain of Drosophila melanogaster to the toxic effects of environmental cigarette smoke Genes Environ. 2009 31 43 46
24. A. Rapp K. O. Greulich After double-strand break induction by UV-A, homologous recombination and nonhomologous end joining cooperate at the same DSB if both systems are available J. Cell Sci. 2004 117 4935 4945
25. R. Greinert B. Volkmer S. Henning E. W. Breitbart K. O. Greulich M. C. Cardoso A. Rapp UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages Nucleic Acids Res. 2012 40 10263 10273
26. J. L. Rizzo J. Dunn A. Rees T. M. Rünger No formation of DNA double-strand breaks and no activation of recombination repair with UVA J. Invest. Dermatol. 2011 131 1139 1148
27. J. R. LaRocque B. Jaklevic T. T. Su J. Sekelsky Drosophila ATR in double-strand break repair Genetics 2007 175 1023 1033
28. A. Kinner W. Wu C. Stauddt G. Iliakis γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin Nucleic Acids Res. 2008 36 5678 5694
29. J. P. Madigan H. L. Chotkowski R. L. Glaser DNA double-strand break-induced phosphorylation of Drosophila histone variant H2Av helps prevent radiation-induced apoptosis Nucleic Acids Res. 2002 30 3698 3705
30. a mutant of Drosophila melanogaster increases mutagen sensitivity and decreases excision repair Genetics 1976 84 527 544
31. J. J. Sekelsky K. S. McKim G. M. Chin R. S. Hawley The Drosophila meiotic recombination gene mei-9 encodes a homologue of the yeast excision repair protein Rad1 Genetics 1995 141 619 627
32. J. B. Boyd R. B. Setlow Characterization of postreplication repair in mutagen-sensitive strains of Drosophila melanogaster Genetics 1976 84 507 526
33. K. L. Hari A. Santerre J. J. Sekelsky K. S. McKim J. B. Boyd R. S. Hawley The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene Cell 1995 82 815 821
34. J. J. Sekelsky M. H. Brodsky K. C. Burtis DNA repair in Drosophila: Insights from the Drosophila genome sequence J. Cell Biol. 2000 150 F31 F36
35. R. C. Wahl C. K. Warner V. Finnerty K. V. Rajagopalan Drosophila melanogaster ma-l mutants are defective in the sulfuration of desulfo Mo hydroxylases J. Biol. Chem. 1982 257 3958 3962
36. D. L. Lindsley and G. G. Zimm, The genome of Drosophila melanogaster, Academic Press, San Diego, 1992
37. U. Graf F. E. Würgler A. J. Katz H. Frei H. Juon C. B. Hall P. G. Kale Somatic mutation and recombination test in Drosophila melanogaster Environ. Mutagen. 1984 6 153 188
38. E. W. Vogel, U. Graf, H.-J. Frei and M. M. J. Nivard, The results of assays in Drosophila as indicators of exposure to carcinogens, in The Use of Short and Medium-term Tests for Carcinogens and Data on Genetic Effects in Carcinogenic Hazard Evaluation, ed., D. B. McGregor, J. M. Rice, and, S. Venitt, IARC Scientific Publications, No. 146, International Agency for Research on Cancer, Lyon, 1999, pp. 427-470
39. H. Frei F. E. Würgler Statistical methods to decide whether mutagenicity test data from Drosophila melanogaster assays indicate a positive, negative, or inconclusive result Mutat. Res. 1988 203 297 308
40. M. A. Kastenbaum K. O. Bowman Tables for determining the statistical significance of mutation frequencies Mutat. Res. 1970 9 527 549
41. A. W. Thorne, P. D. Cary and C. Crane-Robinson, Extraction and separation of core histones and non-histone chromosomal proteins, in Chromatin-A Practical Approach, ed., H. Gould, Oxford University Press, Oxford, UK, 1998, pp. 35-57
42. Y. Ibuki T. Toyooka J. Shirahata T. Ohura R. Goto Water soluble fraction of solar simulated light-exposed crude oil generates phosphorylation of histone H2AX in human skin cells under UVA exposure Environ. Mol. Mutagen. 2007 48 430 439
43. A. J. Ridley J. R. Whiteside T. J. McMillan S. L. Allinson Cellular and sub-cellular responses to UVA in relation to carcinogenesis Int. J. Radiat. Biol. 2009 85 177 195
44. T. Negishi K. Kawai R. Arakawa S. Higashi T. Nakamura M. Watanabe H. Kasai K. Fujikawa Increased levels of 8-hydroxy-2′-deoxyguanosine in Drosophila larval DNA after irradiation with 364 nm-laser light but not with X-rays Photochem. Photobiol. 2007 83 658 663
45. T. M. Rünger U. P. Kappes Mechanisms of mutation formation with long-wave ultraviolet light (UVA) Photodermatol. Photoimmunol. Photomed. 2008 24 2 10
46. H. Ikehata T. Ono The mechanisms of UV mutagenesis J. Radiat. Res. 2011 52 115 52
47. J. D. Mallet P. J. Rochette Wavelength-dependent ultraviolet induction of cyclobutane pyrimidine dimers in the human cornea Photochem. Photobiol. Sci. 2013 12 1310 1318
48. S. Takinamai M. Mochizuki H. Hayatsu O. Nikaido M. Kubota M. Watanabe M. Hieda K. Hieda T. Negishi Somatic cell mutation and photoproduct formation in Drosophila induced by monochromatic UV-lights contained in the sunlight Environ. Toxicol. 2000 15 496 499
49. P. L. Olive J. P. Banáth Phosphorylation of histone H2AX as a measure of radiosensitivity Int. J. Radiat. Oncol., Biol., Phys. 2004 58 331 335
50. A. van Daal E. M. White M. A. Gorovsky C. R. Elgin Drosophila has a single copy of the gene encoding a highly conserved histone H2A variant of the H2A. F/Z type Nucleic Acids Res. 1988 16 7487 7497
51. J. E. Cleaver γH2Ax: Biomarker of damage or functional participant in DNA repair "All that glitters is not gold!" Photochem. Photobiol. 2011 87 1230 1239
52. N. Srivastava S. Gochhait P. de Boer R. N. Bamezai Role of H2AX in DNA damage response and human cancers Mutat. Res. 2009 681 180 188
53. M. A. Spanó H. Frei F. E. Würgler U. Graf Recombinagenic activity of four compounds in the standard and high bioactivation crosses of Drosophila melanogaster in the wing spot test Mutagenesis 2001 16 385 394
54. L. J. Fell N. D. Paul T. J. McMillan Role for non-homologous end-joining in the repair of UVA-induced DNA damage Int. J. Radiat. Biol. 2002 78 1023 1027