PIAS1 and STAT-3 impair the tumoricidal potential of IFN-γ-stimulated mouse dendritic cells generated with IL-15

European Journal of Immunology

Volumn 44, Issue 8, 2014, Pages 2489-2499

  Hanke, Neale T ^a,b   Lacasse, Collin J ^a,b   Larmonier, Claire B ^a   Alizadeh, Darya ^a,b   Trad, Malika ^c   Janikashvili, Nona ^c   Bonnotte, Bernard ^c   Katsanis, Emmanuel ^a,b   Larmonier, Nicolas ^a,b  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c UNIVERSITÉ DE BOURGOGNE   (France)

Author keywords

Cytotoxic dendritic cells; INOS; NF B; PIAS1; STAT 3

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 15; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROTEIN INHIBITOR OF ACTIVATED STAT; PROTEIN INHIBITOR OF ACTIVATED STAT 1; SMALL INTERFERING RNA; STAT1 PROTEIN; STAT3 PROTEIN; TOLL LIKE RECEPTOR 4; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW CELL; CELL KILLING; CELL MATURATION; CELL STIMULATION; CONTROLLED STUDY; CYTOTOXICITY; DENDRITIC CELL; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LYMPHOCYTE PROLIFERATION; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TUMOR CELL;

CYTOTOXIC DENDRITIC CELLS; INOS; NF-ΚB; PIAS1; STAT-3;

ANIMALS; CELL LINE, TUMOR; DENDRITIC CELLS; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERFERON-GAMMA; INTERLEUKIN-15; INTERLEUKIN-4; LIGANDS; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN INHIBITORS OF ACTIVATED STAT; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTOR 4;

EID: 84906095759     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343803     Document Type: Article

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