Innate direct anticancer effector function of human immature dendritic cells. I. Involvement of an apoptosis-inducing pathway

Journal of Immunology

Volumn 168, Issue 4, 2002, Pages 1823-1830

  Janjic, Bratislav M ^a   Lu, Ganwei ^a   Pimenov, Alexei ^a   Whiteside, Theresa L ^a   Storkus, Walter J ^a   Vujanovic, Nikola L ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PARAFORMALDEHYDE; TUMOR ANTIGEN;

ANTIGEN PRESENTATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL KILLING; CELL PROLIFERATION; CONTROLLED STUDY; DENDRITIC CELL; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN SECRETION; T LYMPHOCYTE;

EID: 0037083466     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.4.1823     Document Type: Article

References (26)

1. The dendritic cell system and its role in immunogenicity
2. Mechanisms of dendritic cell function
3. Dendritic cells and the control of immunity
4. Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and Th1-associated cytokines
5. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
6. 5 and CD36 and cross-present antigens to cytotoxic T lymphocytes
7. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells
8. Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
9. Generation of tumor-specific T lymphocytes by cross-priming with human dendritic cells ingesting apoptotic tumor cells
10. Immunogenicity of apoptotic cells in vivo: Role of antigen load, APCs, and cytokines
11. Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
12. The involvement of TNF-α-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-β-stimulated human dendritic cells to tumor cells
13. Dendritic cell activity against primary tumors: An overview
14. Selection of lymphocytes for immunotherapy
15. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α
16. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
17. Nonsecretory apoptotic killing by human NK cells
18. Evaluation of tetrazolium-based semiautomatic colorimetric assay for measurement of human antitumor cytotoxicity
19. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
20. Reduction of mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
21. Distinct phenotypic and functional characteristics of human natural killer cells obtained by rapid interleukin 2-induced adherence to plastic
22. Mitochondria and apoptosis
23. Death receptors: Signaling and modulation
24. Rapid IL-2-induced adherence of human NK cells, expression of mRNA for cytokines and IL-2 receptors in adherent NK cells
25. 2, Fas ligand, and TNF-related apoptosis-inducing ligand
26. 2+-dependent mechanism