Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-α1β2, Fas ligand, and TNF-related apoptosis-inducing ligand

Journal of Immunology

Volumn 168, Issue 4, 2002, Pages 1831-1839

  Lu, Ganwei ^a   Janjic, Bratislav M ^a   Janjic, Jelena ^a   Whiteside, Theresa L ^a   Storkus, Walter J ^a   Vujanovic, Nikola L ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; HYBRID PROTEIN; LYMPHOTOXIN; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER IMMUNOLOGY; CELL KILLING; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION;

EID: 0037083571     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.4.1831     Document Type: Article

References (47)

1. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro
2. Extent and diversity of inflammatory cell infiltrates in squamous cell carcinomas and basal epitheliomas of the head and neck
3. A discreet subpopulation of dendritic cells transports apoptotic intestitial epidermal cells to T cell areas of mesenteric lymph nodes
4. Are dendritic cells the key to liver transplant tolerance
5. MHC class II antigen-bearing dendritic cells in pulmonary tissues of the rat: Regulation of antigen presentation activity by endogenous macrophage populations
6. T-cell apoptosis detected in situ during positive and negative selection in the thymus
7. Dendritic cells and the control of immunity
8. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium
9. Anticancer role of dendritic cells (DC) in human and experimental cancers: A review
10. Flt3 ligand induces tumor regression and antitumor immune responses in vivo
11. Antitumor activity and immunotherapeutic properties of Flt3-ligand in a murine breast cancer model
12. Role of bone marrow-derived cells in presenting MHC class 1-restricted tumor antigens
13. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
14. 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
15. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells
16. Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
17. Generation of tumor-specific T lymphocytes by cross-priming with human dendritic cells ingesting apoptotic tumor cells
18. Immunogenicity of apoptotic cells in vivo: Role of antigen load, antigen-presenting cells, and cytokines
19. A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis
20. Fas ligand (CD95L) and B7 expression on dendritic cells provide counter-regulatory signals for T cell survival and proliferation
21. Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)
22. The involvement of TNF-α-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-β-stimulated human dendritic cells to tumor cells
23. Constitutive expression and role of the TNF family ligands in apoptotic killing of tumor cells by human NK cells
24. Nonsecretory apoptotic killing by human NK cells
25. Evaluation of tetrazolium-based semiautomatic colorimetric assay for measurement of human antitumor cytotoxicity
26. Distinct phenotypic and functional characteristics of human natural killer cells obtained by rapid interleukin 2-induced adherence to plastic
27. Molecular, structural and biological characteristics of the tumor necrosis factor ligand superfamily
28. Tumor necrosis factor and Fas signaling mechanisms
29. Dominant negative mutations of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-β receptor
30. The CTL's kiss of death
31. Expression of surface lymphotoxin and TNF on activated T, B, and NK cells
32. Cytotoxic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
33. Expression of the Fas ligand in cells of T cell lineage
34. Natural killer (NK) cell-mediated cytotoxicity: Differential use of TRAIL and Fas ligand by immature and mature primary human NK cells
35. Perforin, Fas ligand, and tumor necrosis factor are the major cytotoxic molecules used by lymphokine-activated killer cells
36. A novel addition to the T cell repertory cell surface expression of tumor necrosis factor/cachectin by activated normal human T cells
37. Membrane form of TNF-α induces both cell lysis and apoptosis in susceptible target cells
38. Soluble and membrane-bound TNF-α are involved in the cytotoxic activity of B cells from tumor-bearing mice against tumor targets
39. + T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor
40. TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells
41. Surface expression of TRAIL/Apo-2 ligand in activated mouse T and B cells
42. + T cell-mediated cytotoxicity
43. Bystander apoptosis triggers dendritic cell maturation and antigen-presenting function
44. Inhibition of death receptor signaling by FLICE-inhibitory protein as a mechanism of immune escape of tumors
45. TRAIL/Apo-2-ligand-induced apoptosis in human T cells
46. Signaling by the TNF receptor superfamily and T cell homeostasis
47. Innate direct anticancer effector function of human immature dendritic cells. I. Involvement of an apoptosis-inducing pathway