Age dependency of safety and outcome of endovascular therapy for acute stroke

Journal of Neurology

Volumn 261, Issue 8, 2014, Pages 1622-1627

  Luedi, Rudolf ^a   Hsieh, Kety ^a   Slezak, Agnieszka ^a   El Koussy, Marwan ^a   Fischer, Urs ^a   Heldner, Mirjam R ^a   Meisterernst, Julia ^a   Mono, Marie Luise ^a   Zubler, Christoph ^a   Mordasini, Pasquale ^a   Ozdoba, Christoph ^a   Mattle, Heinrich P ^a   Schroth, Gerhard ^a   Gralla, Jan ^a   Arnold, Marcel ^a   Jung, Simon ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Age; Endovascular therapy; Intra arterial thrombolysis; Outcome

Indexed keywords

ADULT; AGE; AGED; ARTICLE; BLEEDING; BRAIN HEMORRHAGE; CEREBROVASCULAR ACCIDENT; ENDOVASCULAR SURGERY; FEMALE; GERIATRIC PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OUTCOME ASSESSMENT; PATIENT SAFETY; PRIORITY JOURNAL; RANKIN SCALE; RECANALIZATION; SURVIVAL; VERY ELDERLY; YOUNG ADULT; ACUTE DISEASE; AGING; COHORT ANALYSIS; MORTALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES; STATISTICAL MODEL; STROKE;

ACUTE DISEASE; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; COHORT STUDIES; ENDOVASCULAR PROCEDURES; FEMALE; HUMANS; LOGISTIC MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); STROKE; YOUNG ADULT;

EID: 84906083268     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-014-7401-0     Document Type: Article

References (29)

1. Kelly-Hayes M, Beiser A, Kase CS, Scaramucci A, D'Agostino RB, Wolf PA (2003) The influence of gender and age on disability following ischemic stroke: the Framingham study. J Stroke Cerebrovasc Dis 12(3):119-126
2. Dennis MS, Burn JP, Sandercock PA, Bamford JM, Wade DT, Warlow CP (1993) Long-term survival after first-ever stroke: the Oxfordshire Community Stroke Project. Stroke 24(6):796-800
3. Heuschmann PU, Kolominsky-Rabas PL, Misselwitz B, Hermanek P, Leffmann C, Janzen RW et al (2004) Predictors of in-hospital mortality and attributable risks of death after ischemic stroke: the German Stroke Registers Study Group. Arch Intern Med 164(16):1761-1768
4. Sylaja PN, Cote R, Buchan AM, Hill MD (2006) Thrombolysis in patients older than 80 years with acute ischaemic stroke: Canadian Alteplase for Stroke Effectiveness Study. J Neurol Neurosurg Psychiatry 77(7):826-829
5. Mishra NK, Ahmed N, Andersen G, Egido JA, Lindsberg PJ, Ringleb PA et al (2010) Thrombolysis in very elderly people: controlled comparison of SITS International Stroke Thrombolysis Registry and Virtual International Stroke Trials Archive. BMJ 341:c6046
6. Mishra NK, Diener HC, Lyden PD, Bluhmki E, Lees KR (2010) Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA). Stroke 41(12):2840-2848
7. The NINDS t-PA Study Group (1997) Generalized efficacy of t-PA for acute stroke. Subgroup analysis of the NINDS t-PA Stroke Trial. Stroke 28(11):2119-2125
8. Poppe AY, Buchan AM, Hill MD (2009) Intravenous thrombolysis for acute ischaemic stroke in young adult patients. Can J Neurol Sci (Le journal canadien des sciences neurologiques) 36(2):161-167
9. Putaala J, Metso TM, Metso AJ, Makela E, Haapaniemi E, Salonen O et al (2009) Thrombolysis in young adults with ischemic stroke. Stroke 40(6):2085-2091
10. Meseguer E, Labreuche J, Olivot JM, Abboud H, Lavallee PC, Simon O et al (2008) Determinants of outcome and safety of intravenous rt-PA therapy in the very old: a clinical registry study and systematic review. Age Ageing 37(1):107-111
11. Engelter ST, Bonati LH, Lyrer PA (2006) Intravenous thrombolysis in stroke patients of ≥80 versus <80 years of age - a systematic review across cohort studies. Age Ageing 35(6):572-580
12. Ford GA, Ahmed N, Azevedo E, Grond M, Larrue V, Lindsberg PJ et al (2010) Intravenous alteplase for stroke in those older than 80 years old. Stroke 41(11):2568-2574 Epub 2010/10/12
13. Toni D, Ahmed N, Anzini A, Lorenzano S, Brozman M, Kaste M et al (2012) Intravenous thrombolysis in young stroke patients: results from the SITS-ISTR. Neurology 78(12):880-887
14. The IMS Study Investigators (2004) Combined intravenous and intra-arterial recanalization for acute ischemic stroke: the Interventional Management of Stroke Study. Stroke 35(4):904-911
15. The IMS II Trial Investigators (2007) The Interventional Management of Stroke (IMS) II Study. Stroke 38(7):2127-2135
16. Ciccone A, Valvassori L, Nichelatti M, Sgoifo A, Ponzio M, Sterzi R et al (2013) Endovascular treatment for acute ischemic stroke. N Engl J Med 368(10):904-913
17. Furlan A, Higashida R, Wechsler L, Gent M, Rowley H, Kase C et al (1999) Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in acute cerebral thromboembolism. JAMA 282(21):2003-2011
18. Broderick JP, Palesch YY, Demchuk AM, Yeatts SD, Khatri P, Hill MD et al (2013) Endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med 368(10):893-903
19. Kidwell CS, Jahan R, Gornbein J, Alger JR, Nenov V, Ajani Z et al (2013) A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med 368(10):914-923
20. Mono ML, Romagna L, Jung S, Arnold M, Galimanis A, Fischer U et al (2012) Intra-arterial thrombolysis for acute ischemic stroke in octogenarians. Cerebrovasc Dis 33(2):116-122
21. Qureshi AI, Suri MF, Georgiadis AL, Vazquez G, Janjua NA (2009) Intra-arterial recanalization techniques for patients 80 years or older with acute ischemic stroke: pooled analysis from 4 prospective studies. AJNR 30(6):1184-1189
22. Kim D, Ford GA, Kidwell CS, Starkman S, Vinuela F, Duckwiler GR et al (2007) Intra-arterial thrombolysis for acute stroke in patients 80 and older: a comparison of results in patients younger than 80 years. AJNR 28(1):159-163
23. Pundik S, McWilliams-Dunnigan L, Blackham KL, Kirchner HL, Sundararajan S, Sunshine JL et al (2008) Older age does not increase risk of hemorrhagic complications after intravenous and/or intra-arterial thrombolysis for acute stroke. J Stroke Cerebrovasc Dis 17(5):266-272
24. Chandra RV, Leslie-Mazwi TM, Oh DC, Chaudhry ZA, Mehta BP, Rost NS et al (2012) Elderly patients are at higher risk for poor outcomes after intra-arterial therapy. Stroke 43(9):2356-2361
25. Galimanis A, Jung S, Mono ML, Fischer U, Findling O, Weck A et al (2012) Endovascular therapy of 623 patients with anterior circulation stroke. Stroke 43(4):1052-1057
26. Jung S, Schindler K, Findling O, Mono ML, Fischer U, Gralla J et al (2012) Adverse effect of early epileptic seizures in patients receiving endovascular therapy for acute stroke. Stroke 43(6):1584-1590
27. Jung S, Mono ML, Fischer U, Galimanis A, Findling O, De Marchis GM et al (2011) Three-month and long-term outcomes and their predictors in acute basilar artery occlusion treated with intra-arterial thrombolysis. Stroke 42(7):1946-1951
28. Kase CS, Furlan AJ, Wechsler LR, Higashida RT, Rowley HA, Hart RG et al (2001) Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke: the PROACT II trial. Neurology 57(9):1603-1610
29. Sandercock P, Wardlaw JM, Lindley RI, Dennis M, Cohen G, Murray G et al (2012) The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet 379(9834):2352-2363