Discovery and refinement of muscle weight QTLs in B6 × D2 advanced intercross mice

Physiological Genomics

Volumn 46, Issue 16, 2014, Pages 571-582

  Carbonetto, P ^b   Cheng, R ^c   Gyekis, J P ^d   Parker, C C ^e   Blizard, D A ^d   Palmer, A A ^b   Lionikas, A ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF CHICAGO   (United States)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

^e MIDDLEBURY COLLEGE   (United States)

Author keywords

Advanced intercross line; Complex trait QTLs; Forward genetics; Genetic architecture; Genomewide association studies; Hypertrophy; Inbred strains; Linear mixed models; Mouse genetics; Muscle wasting; QTL mapping; Quantitative trait loci

Indexed keywords

ADVANCED INTERCROSS LINE; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ARTICLE; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE MAPPING; GENETIC DISTANCE; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HINDLIMB; INBRED STRAIN; MALE; MISSENSE MUTATION; MOUSE; MUSCLE DEVELOPMENT; MUSCLE MASS; NONHUMAN; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN FUNCTION; QUANTITATIVE TRAIT LOCUS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; ANATOMY AND HISTOLOGY; ANIMAL; C57BL MOUSE; CHROMOSOME; CHROMOSOME MAP; CROSS BREEDING; DBA MOUSE; GENETIC LINKAGE; GENETICS; GENOME; METABOLISM; ORGAN SIZE; PROCEDURES; SEX DIFFERENCE; SKELETAL MUSCLE; STOP CODON;

STOP CODON;

ANIMALS; CHROMOSOME MAPPING; CHROMOSOMES, MAMMALIAN; CODON, NONSENSE; CROSSES, GENETIC; FEMALE; GENE FREQUENCY; GENOME; HINDLIMB; LOD SCORE; MALE; MICE, INBRED C57BL; MICE, INBRED DBA; MUSCLE, SKELETAL; MUTATION, MISSENSE; ORGAN SIZE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; SEX FACTORS;

EID: 84906077788     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00055.2014     Document Type: Article

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