In vivo and in vitro evidence that 99mTc-HYNIC-interleukin-2 is able to detect T lymphocytes in vulnerable atherosclerotic plaques of the carotid artery

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 41, Issue 9, 2014, Pages 1710-1719

  Glaudemans, Andor W J M ^a   Bonanno, Elena ^b   Galli, Filippo ^c   Zeebregts, Clark J ^a   De Vries, Erik F J ^a   Koole, Michel ^a   Luurtsema, Gert ^a   Boersma, Hendrikus H ^a   Taurino, Maurizio ^d   Slart, Riemer H J A ^a   Signore, Alberto ^a,c  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Atherosclerosis; SPECT CT; Vulnerable plaque

Indexed keywords

CD3 ANTIGEN; HYDRAZINONICOTINAMIDE INTERLEUKIN 2 TC 99M; INTERLEUKIN 2 RECEPTOR ALPHA; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; 99MTC-HYNIC-INTERLEUKIN-12; INTERLEUKIN 12; TECHNETIUM COMPLEX;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; AUTORADIOGRAPHY; CAROTID ARTERY; CAROTID ENDARTERECTOMY; CD25+ T LYMPHOCYTE; CLINICAL ARTICLE; COMPUTER ASSISTED SCINTIGRAPHY; CT SPECT SCANNER; DIAGNOSTIC IMAGING; ECHOCARDIOGRAPHY; EX VIVO STUDY; FEMALE; HUMAN; IMAGE ANALYSIS; IMMUNOPHARMACOLOGY; IMMUNOPHENOTYPING; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LYMPHOCYTIC INFILTRATION; MALE; RADIOISOTOPE DISTRIBUTION; SENSITIVITY AND SPECIFICITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; T LYMPHOCYTE; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC USE; IMMUNOLOGY; METABOLISM; MIDDLE AGED; MULTIMODAL IMAGING; PATHOLOGY; PLAQUE, ATHEROSCLEROTIC; RADIOGRAPHY; SCINTISCANNING; TRANSPORT AT THE CELLULAR LEVEL;

AGED; AUTORADIOGRAPHY; BIOLOGICAL TRANSPORT; CAROTID ARTERIES; FEMALE; HUMANS; INTERLEUKIN-12; MALE; MIDDLE AGED; MULTIMODAL IMAGING; ORGANOTECHNETIUM COMPOUNDS; PLAQUE, ATHEROSCLEROTIC; T-LYMPHOCYTES; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84906062899     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-014-2764-0     Document Type: Article

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