Strategies to fine-map genetic associations with lipid levels by combining epigenomic annotations and liver-specific transcription profiles

Genomics

Volumn 104, Issue 2, 2014, Pages 105-112

  Lo, Ken Sin ^a   Vadlamudi, Swarooparani ^b   Fogarty, Marie P ^b   Mohlke, Karen L ^b   Lettre, Guillaume ^a,c  

^a MONTREAL HEART INSTITUTE   (Canada)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

BIRC5; ENCODE; FOXA1; FOXA2; GWAS; HNF4A

Indexed keywords

FOXA2 PROTEIN, HUMAN; HEPATOCYTE NUCLEAR FACTOR 3BETA; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, HUMAN; LIPID; PROTEIN BINDING; TRANSCRIPTION FACTOR; TRANSCRIPTOME;

ALLELE; ANIMAL; BINDING SITE; CHEMISTRY; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOMAL MAPPING; EPIGENETICS; GENETIC ASSOCIATION STUDY; GENETICS; HEPG2 CELL LINE; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN GENOME; K562 CELL LINE; KNOCKOUT MOUSE; LIVER; METABOLISM; MOUSE; PHENOTYPE; PROCEDURES; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ANIMALS; BINDING SITES; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME MAPPING; EPIGENOMICS; GENETIC ASSOCIATION STUDIES; GENOME, HUMAN; HEP G2 CELLS; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HEPATOCYTE NUCLEAR FACTOR 4; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; K562 CELLS; LIPIDS; LIVER; MICE; MICE, KNOCKOUT; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; QUANTITATIVE TRAIT LOCI; TRANSCRIPTION FACTORS; TRANSCRIPTOME;

EID: 84906047240     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2014.04.006     Document Type: Article

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