Dissection of the adenoviral VA RNAI central domain structure reveals minimum requirements for RNA-mediated inhibition of PKR

Journal of Biological Chemistry

Volumn 289, Issue 33, 2014, Pages 23233-23245

  Wilson, Jo L ^a   Vachon, Virginia K ^a   Sunita, S ^a   Schwartz, Samantha L ^a   Conn, Graeme L ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOTIDES; VIRUSES;

BINDING ASSAYS; DOMAIN STRUCTURE; INHIBITORY ACTIVITY; INNATE IMMUNE SYSTEMS; MINIMUM REQUIREMENTS; NON-CODING RNAS; PROTEIN KINASE; TERTIARY STRUCTURES;

RNA;

MAGNESIUM ION; PROTEIN KINASE R; UNCLASSIFIED DRUG; UNTRANSLATED RNA; VIRUS ASSOCIATED RNA I; ADENOVIRUS ASSOCIATED RNA; MAGNESIUM; VIRUS RNA;

ADENOVIRUS; ARTICLE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; MUTAGENESIS; NONHUMAN; PH; PRIORITY JOURNAL; RNA SEQUENCE; RNA STRUCTURE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ADENOVIRIDAE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CONFORMATION; GENETICS; METABOLISM;

ADENOVIRIDAE; EIF-2 KINASE; HYDROGEN-ION CONCENTRATION; MAGNESIUM; MUTAGENESIS; NUCLEIC ACID CONFORMATION; RNA, VIRAL;

EID: 84905970441     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.550046     Document Type: Article

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