The effect of outdoor fungal spore concentrations on daily asthma severity

Environmental Health Perspectives

Volumn 105, Issue 6, 1997, Pages 622-635

  Delfino, Ralph J ^a,b   Zeiger, Robert S ^c,d   Seltzer, James M ^c,e   Street, Donald H ^f   Matteucci, Reneé M ^a   Anderson, Patrick R ^a   Koutrakis, Petros ^g  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d Southern California Permanente Medical Group   (United States)

^e Clinical Research Institute Inc   (United States)

^f BAYER CORPORATION   (United States)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Alternaria; Asthma; Basidiomycete; Epicutaneous allergen skin tests; Epidemiology; Longitudinal data analysis; Ozone; Panel study; Particulate air pollution

Indexed keywords

ALLERGEN; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; OZONE;

ADOLESCENT; ADULT; AIR CONDITIONING; AIR POLLUTION; AIR TEMPERATURE; ALTERNARIA; ARTICLE; ASTHMA; CLINICAL ARTICLE; DISEASE SEVERITY; FEMALE; FUNGUS HYPHAE; FUNGUS SPORE; HUMAN; INHALATIONAL DRUG ADMINISTRATION; MALE; NONHUMAN; PARTICULATE MATTER; PEAK EXPIRATORY FLOW; POLLEN; PRIORITY JOURNAL; REGRESSION ANALYSIS; SCHOOL CHILD; UNITED STATES; WEATHER;

ALTERNARIA; DEUTEROMYCETE; FUNGI;

EID: 0030871074     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.97105622     Document Type: Article

References (47)

1. Burrows B, Martinez FD, Halonen M, Barbee RA, Cline MG. Association of asthma with serum IgE levels and skin-test reactivity to allergens. N Engl J Med 320:271-277 (1989).
2. NHLBI. National Asthma Education Program, Expert Panel Report: Guidelines for the Diagnosis and Management of Asthma. U.S. Department of Public Health Publications No. 91-3042, Bethesda, MD:National Heart, Lung, and Blood Institute, 1991.
3. Klabuschnigg A, Götz M, Horak F, Jäger S, Machalek A, Popow C, Haschke F, Skoda-Türk R. Influence of aerobiology and weather on symptoms in children with asthma. Respiration 42:52-60 (1981).
4. Beaumont F, Kauffman HF, Sluiter HJ, De Vries K. Sequential sampling of fungal air spores inside and outside the homes of mould-sensitive, asthmatic patients: a search for a relationship to obstructive reactions. Ann Allergy 55:740-746 (1985).
5. O'Hollaren MT, Yunginger JW, Offord KP, Somers MJ, O'Connell EJ, Ballard DJ, Sachs MI. Exposure to an aeroallergen as a possible precipitating factor in respiratory arrest in young patients with asthma. N Engl J Med 324:359-363 (1991).
6. Salvaggio J, Seabury J, Schoenhardt E. New Orleans asthma. V. Relationship between Charity Hospital asthma admission rates, semi-quantitative pollen and fungal spore counts, and total particulate aerometric sampling data. J Allergy Clin Immunol 48:96-114 (1971).
7. Jenkins PF, Mullins J, Davies BH, Williams DA. The possible role of aeroallergens in the epidemic of asthma deaths. Clin Allergy 11:611-620 (1980).
8. Hasnain SM, Wilson JD, Newhook FJ. Fungal allergy and respiratory disease. NZ Med J 98:342-346 (1985).
9. Reid MJ, Moss RB, Hsu Y-P, Kwasnicki JM, Commerford TM, Nelson BL. Seasonal asthma in northern California: allergic causes and efficacy of immunotherapy. J Allergy Clin Immunol 78:590-600 (1986).
10. Molfino NA, Slutsky AS, Zamel N. The effects of air pollution on allergic bronchial responsiveness. Clin Exp Allergy 22:667-672 (1992).
11. Delfino RJ, Coate B, Zeiger RS, Seltzer JM, Street DH, Koutrakis P. Daily asthma severity in relation to personal ozone exposure and outdoor fungal spores. Am J Respir Crit Care Med 154:633-6341 (1996).
12. Liu L-J S, Delfino R, Koutrakis P. Ozone exposure assessment in a Southern California community. Environ Health Perspect 105:58-65 (1997).
13. Peters JM. Epidemiologic Investigation to Identify Chronic Health Effects of Ambient Air Pollutants: Phase I Final Report, Phase II Protocol. California Air Resources Board contract #A033-186. Sacramento, CA:California Air Resources Board, 1992.
14. Ellis MH, Gallup J. Aeroallergens of Southern California. Airborne Allergens 9:365-380 (1989).
15. 10 measurements using the tapered element oscillating microbalance. J Air Waste Manage Assoc 41:1079-1083 (1991).
16. Koutrakis P, Wolfson JM, Bunyaviroch A, Froehlich SE, Hirano K, Mulik JD. Measurement of ambient ozone using a nitrite-coated filter. Anal Chem 65:209-214 (1993).
17. Liu L-J S, Koutrakis P, Suh HH, Mulik JD, Burton RM. Use of personal measurements for ozone exposure assessment: a pilot study. Environ Health Perspect 101:318-324 (1993).
18. Liu L-J S, Koutrakis P, Olson MP, Allen GA, McDonnell WF, Gerrity TR. Evaluation of the Harvard ozone passive sampler on human subjects indoors. Environ Sci Technol 28:915-923 (1994).
19. SAS Institute Inc. SAS Technical Report P-229, SAS/STAT Software: Changes and Enhancements, Release 6.07. Cary, NC:SAS Institute Inc, 1992.
20. Jennrich RI, Schluchter MD. Unbalanced repeated-measures models with structured covariance matrices. Biometrics 42:805-820 (1986).
21. Lindstrom MJ, Bates DM. Newton-Raphson and EM algorithms for linear mixed-effects models for repeated-measures data. J Am Stat Assoc 83:1014-1022 (1988).
22. Dhillon M. Current status of mold immunotherapy. Ann Allergy 66:385-392 (1991).
23. Polgar G, Promadhat V. Pulmonary Function Testing in Children: Techniques and Standards. Philadelphia:W. B. Saunders Company, 1971.
24. Leiner GC, Abramowitz S, Small MJ, Stenby VB, Lewis WA. Expiratory peak flow rate. Standard values for normal subjects. Use as a clinical test of ventilatory function. Am Rev Respir Dis 88:644-651 (1963).
25. Levetin E. Fungi. In: Bioaerosols (Burge H, ed). Ann Arbor, MI:Lewis Publishers, 1995.
26. Metzger WJ, Richerson HB, Worden K, Monick M, Hunninghake GW. Bronchoalveolar lavage of allergic asthmatic patients following allergen bronchoprovocation. Chest 89:477-483 (1986).
27. Licorish K, Novey HS, Kozak P, Fairshtet RD, Wilson AF. Role of Alternaria and Penicillium spores in the pathogenesis of asthma. J Allergy Clin Immunol 76:819-825 (1985).
28. Targonski PV, Persky VW, Ramekrishnan V. Effect of environmental molds on risk of death from asthma during the pollen season. J Allergy Clin Immunol 95:955-961 (1995).
29. American Thoracic Society. Guidelines as to what constitutes an adverse respiratory health effect, with special reference to epidemiologic studies of air pollution. Am Rev Respir Dis 131:666-668 (1985).
30. Kleinbaum DG, Kupper LL, Muller KE. Applied Regression Analysis and Other Multivariable Methods. Boston:PWS-KENT Publishing Company, 1988.
31. Burge H. Bioaerosols: prevalence and health effects in the indoor environment. J Allergy Clin Immunol 86:687-701 (1990).
32. Lehrer SB, Hughes JM, Altman LC, Bousquet J, Davies RJ, Cell L, Li J, Lopez M, Mailing JF, Mathison DA. Prevalence of basidiomycete allergy in the USA and Europe and its relationship to allergic respiratory symptoms. Allergy 49:460-465 (1994).
33. Lopez M, Viogtlander JR, Lehrer SB, Salvaggio JE. Bronchoprovocation studies in basidiospore-sensitive allergic subjects with asthma. J Allergy Clin Immunol 84:243-246 (1989).
34. Solomon WR, Burge HP, Biose JR. Exclusion of particulate allergens by window air conditioners. J Allergy Clin Immunol 65:305 (1980).
35. Wickman M, Gravesen S, Nordvall SL, Pershagen G, Sundell J. Indoor viable dustbound microfungi in relation to residential characteristics, living habits, and symptoms in atopic and control children. J Allergy Clin Immunol 89:752-759 (1992).
36. Korsgaard J. House dust mites and absolute indoor humidity. Allergy 38:88-92 (1983).
37. Sakaguchi M, Inouye S, Sasaki R, Hashimoto M, Kobayashi C, Yasueda H. Measurement of airborne mite allergen exposure in individual subjects. J Allergy Clin Immunol 97:1040-1044 (1996).
38. Balmes J. The role of ozone in the epidemiology of asthma. Environ Health Perspect 101(suppl 4):219-224 (1993).
39. Verschelden P, Cartier A, L'Archeveque J, Trudeau C, Malo JL. Compliance with and accuracy of daily self-assessment of peak expiratory flows (PEF) in asthmatic subjects over a three-month period. Am J Respir Crit Care Med 153:A771 (1996).
40. Hyland ME, Kenyon CAP, Allen R, Howarth P. Diary keeping in asthma: comparison of written and electronic methods. BMJ 306:487-489 (1993).
41. Louis TA, Lavori PW, Bailar JC, Polansky M. Crossover and self-controlled designs in clinical research. N Engl J Med 310:24-31 (1984).
42. Weiss ST, Ware JH. Overview of issues in the longitudinal analysis of respiratory data. Am J Respir Crit Care Med 154:S208-S211 (1996).
43. Rothman KJ. Modern Epidemiology. Boston: Little, Brown & Co, 1986.
44. Neas LM, Dockery DW, Koutrakis P, Tollerud DJ, Speizer FE. The association of ambient air pollution with twice daily peak expiratory flow rate measurements in children. Am J Epidemiol 141:111-122 (1995).
45. Hoek G, Fischer P, Brunekreef B, Lebret E, Hofschreuder P, Mennen MG. Acute effects of ambient ozone on pulmonary function of children in the Netherlands. Am Rev Respir Dis 147:111-117 (1993).
46. Brunekreef B, Kinney PL, Ware JH, Dockery D, Speizer FE, Spengler JD, Ferris BG Jr. Sensitive subgroups and normal variation in pulmonary function response to air pollution episodes. Environ Health Perspect 90:189-193 (1991).
47. Burden JG, Juniper EF, Killian KJ, Hargreave FE, Campbell EJ. The preception of breathlessness in asthma. Am Rev Respir Dis 126:825-828 (1982).