-
1
-
-
0024509701
-
Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
-
Choo, Q. L., Kuo, G., Weiner, A. J., Overby, L. R., Bradley, D. W. and Houghton, M. (1989) Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244, 359-362 (Pubitemid 19117877)
-
(1989)
Science
, vol.244
, Issue.4902
, pp. 359-362
-
-
Choo, Q.-L.1
Kuo, G.2
Weiner, A.J.3
Overby, L.R.4
Bradley, D.W.5
Houghton, M.6
-
2
-
-
0035918320
-
Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A
-
Arima, N., Kao, C. Y., Licht, T., Padmanabhan, R., Sasaguri, Y. and Padmanabhan, R. (2001) Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A. J. Biol. Chem. 276, 12675-12684
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12675-12684
-
-
Arima, N.1
Kao, C.Y.2
Licht, T.3
Padmanabhan, R.4
Sasaguri, Y.5
Padmanabhan, R.6
-
3
-
-
14844349109
-
The oncogenic potential of hepatitis C virus NS5A sequence variants is associated with PKR regulation
-
DOI 10.1089/jir.2005.25.152
-
Gimenez-Barcons, M., Wang, C., Chen, M., Sanchez-Tapias, J. M., Saiz, J. C. and Gale, Jr, M. (2005) The oncogenic potential of hepatitis C virus NS5A sequence variants is associated with PKR regulation. J. Interferon. Cytokine Res. 25, 152-164 (Pubitemid 40354835)
-
(2005)
Journal of Interferon and Cytokine Research
, vol.25
, Issue.3
, pp. 152-164
-
-
Gimenez-Barcons, M.1
Wang, C.2
Chen, M.3
Sanchez-Tapias, J.-M.4
Saiz, J.-C.5
Gale Jr., M.6
-
4
-
-
0035947270
-
How hepatitis C virus counteracts the interferon response: The jury is still out on NS5A
-
DOI 10.1006/viro.2001.0885
-
Tan, S. L. and Katze, M. G. (2001) How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A. Virology 284, 1-12 (Pubitemid 32476690)
-
(2001)
Virology
, vol.284
, Issue.1
, pp. 1-12
-
-
Tan, S.-L.1
Katze, M.G.2
-
5
-
-
4544336360
-
Hepatitis C virus NS5A: Tales of a promiscuous protein
-
DOI 10.1099/vir.0.80204-0
-
Macdonald, A. and Harris, M. (2004) Hepatitis C virus NS5A: tales of a promiscuous protein. J. Gen. Virol. 85, 2485-2502 (Pubitemid 39214345)
-
(2004)
Journal of General Virology
, vol.85
, Issue.9
, pp. 2485-2502
-
-
Macdonald, A.1
Harris, M.2
-
6
-
-
84865086668
-
HCV NS5A disrupts STAT1 phosphorylation and suppresses type i IFN signaling
-
Kumthip, K., Chusri, P., Jilg, N., Zhao, L., Fusco, D. N., Zhao, H., Goto, K., Cheng, D., Schaefer, E. A., Zhang, L. et al. (2012) HCV NS5A disrupts STAT1 phosphorylation and suppresses type I IFN signaling. J. Virol. 86, 8581-8591
-
(2012)
J. Virol.
, vol.86
, pp. 8581-8591
-
-
Kumthip, K.1
Chusri, P.2
Jilg, N.3
Zhao, L.4
Fusco, D.N.5
Zhao, H.6
Goto, K.7
Cheng, D.8
Schaefer, E.A.9
Zhang, L.10
-
7
-
-
84856828353
-
Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation
-
George, A., Panda, S., Kudmulwar, D., Chhatbar, S. P., Nayak, S. C. and Krishnan, H. H. (2012) Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation. J. Biol. Chem. 287, 5042-5058
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 5042-5058
-
-
George, A.1
Panda, S.2
Kudmulwar, D.3
Chhatbar, S.P.4
Nayak, S.C.5
Krishnan, H.H.6
-
8
-
-
0020356106
-
Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotc initiation factor 3 and a cap binding protein complex
-
Etchison, D., Milburn, S. C., Edery, I., Sonenberg, N. and Hershey, J. W. (1982) Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex. J. Biol. Chem. 257, 14806-14810 (Pubitemid 13159573)
-
(1982)
Journal of Biological Chemistry
, vol.257
, Issue.24
, pp. 14806-14810
-
-
Etchison, D.1
Milburn, S.C.2
Edery, I.3
-
9
-
-
0029890687
-
Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus
-
DOI 10.1073/pnas.93.11.5578
-
Gingras, A. C., Svitkin, Y., Belsham, G. J., Pause, A. and Sonenberg, N. (1996) Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus. Proc. Natl. Acad. Sci. U.S.A. 93, 5578-5583 (Pubitemid 26159493)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.11
, pp. 5578-5583
-
-
Gingras, A.-C.1
Svitkin, Y.2
Belsham, G.J.3
Pause, A.4
Sonenberg, N.5
-
10
-
-
0029976319
-
The C-terminal domain of eukaryotic protein synthesis initiation factor (elF) 4G is sufficient to support cap-independent translation in the absence of elF4E
-
Ohlmann, T., Rau, M., Pain, V. M. and Morley, S. J. (1996) The C-terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap-independent translation in the absence of eIF4E. EMBO J. 15, 1371-1382 (Pubitemid 26093473)
-
(1996)
EMBO Journal
, vol.15
, Issue.6
, pp. 1371-1382
-
-
Ohlmann, T.1
Rau, M.2
Pain, V.M.3
Morley, S.J.4
-
11
-
-
1842831274
-
Phosphorylation of eIF4E by Mnk-1 enhances HSV-1 translation and replication in quiescent cells
-
DOI 10.1101/gad.1185304
-
Walsh, D. and Mohr, I. (2004) Phosphorylation of eIF4E by Mnk-1 enhances HSV-1 translation and replication in quiescent cells. Genes Dev. 18, 660-672 (Pubitemid 38489934)
-
(2004)
Genes and Development
, vol.18
, Issue.6
, pp. 660-672
-
-
Walsh, D.1
Mohr, I.2
-
12
-
-
81255160914
-
Viral subversion of the host protein synthesis machinery
-
Walsh, D. and Mohr, I. (2011) Viral subversion of the host protein synthesis machinery. Nat. Rev. Microbiol. 9, 860-875
-
(2011)
Nat. Rev. Microbiol.
, vol.9
, pp. 860-875
-
-
Walsh, D.1
Mohr, I.2
-
13
-
-
77957025367
-
Viral strategies to subvert the mammalian translation machinery
-
Roberts, L. O., Jopling, C. L., Jackson, R. J. and Willis, A. E. (2009) Viral strategies to subvert the mammalian translation machinery. Prog. Mol. Biol. Transl. Sci. 90, 313-367
-
(2009)
Prog. Mol. Biol. Transl. Sci.
, vol.90
, pp. 313-367
-
-
Roberts, L.O.1
Jopling, C.L.2
Jackson, R.J.3
Willis, A.E.4
-
14
-
-
33846991130
-
The mechanism of translation initiation in eukaryotes
-
(Mathews, M. B., Sonenberg, N. and Hershey, J. W. B., eds, Cold Spring Harbor Laboratory Press, Cold Spring Harbor
-
Pestova, T. V., Lorsch, J. R and Hellen, C. U. T. (2007) The mechanism of translation initiation in eukaryotes. In Translational Control in Biology and Medicine (Mathews, M. B., Sonenberg, N. and Hershey, J. W. B., eds), pp. 87-128, Cold Spring Harbor Laboratory Press, Cold Spring Harbor
-
(2007)
Translational Control in Biology and Medicine
, pp. 87-128
-
-
Pestova, T.V.1
Lorsch, J.R.2
Hellen, C.U.T.3
-
15
-
-
0344758983
-
Starting the protein synthesis machine: Eukaryotic translation initiation
-
DOI 10.1002/bies.10362
-
Preiss, T. and Hentze, M. W. (2003) Starting the protein synthesis machine: eukaryotic translation initiation. Bioessays 25, 1201-1211 (Pubitemid 37499320)
-
(2003)
BioEssays
, vol.25
, Issue.12
, pp. 1201-1211
-
-
Preiss, T.1
Hentze, M.W.2
-
16
-
-
75149196287
-
The mechanism of eukaryotic translation initiation and principles of its regulation
-
Jackson, R. J., Hellen, C. U. and Pestova, T. V. (2010) The mechanism of eukaryotic translation initiation and principles of its regulation. Nat. Rev. Mol. Cell Biol. 11, 113-127
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 113-127
-
-
Jackson, R.J.1
Hellen, C.U.2
Pestova, T.V.3
-
17
-
-
5044229348
-
Molecular mechanisms of translational control
-
DOI 10.1038/nrm1488
-
Gebauer, F. and Hentze, M. W. (2004) Molecular mechanisms of translational control. Nat. Rev. Mol. Cell Biol. 5, 827-835 (Pubitemid 39336276)
-
(2004)
Nature Reviews Molecular Cell Biology
, vol.5
, Issue.10
, pp. 827-835
-
-
Gebauer, F.1
Hentze, M.W.2
-
18
-
-
0025314596
-
Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5 cap
-
Lazaris-Karatzas, A., Montine, K. S. and Sonenberg, N. (1990) Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5 cap. Nature 345, 544-547
-
(1990)
Nature
, vol.345
, pp. 544-547
-
-
Lazaris-Karatzas, A.1
Montine, K.S.2
Sonenberg, N.3
-
19
-
-
84905916817
-
-
(Mathews, M. B., Sonenberg, N. and Hershey, J. W. B., eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor
-
Schneider, R. J. and Sonenberg, N. (2007) Translational control in cancer development and progression. In Translational Control in Biology and Medicine (Mathews, M. B., Sonenberg, N. and Hershey, J. W. B., eds), pp. 87-128, Cold Spring Harbor Laboratory Press, Cold Spring Harbor
-
(2007)
Translational Control in Cancer Development and Progression. in Translational Control in Biology and Medicine
, pp. 87-128
-
-
Schneider, R.J.1
Sonenberg, N.2
-
20
-
-
2342489456
-
EIF-4E expression and its role in malignancies and metastases
-
DOI 10.1038/sj.onc.1207545
-
De Benedetti, A. and Graff, J. R. (2004) eIF-4E expression and its role in malignancies and metastases. Oncogene 23, 3189-3199 (Pubitemid 38638830)
-
(2004)
Oncogene
, vol.23
, Issue.18
, pp. 3189-3199
-
-
De Benedetti, A.1
Graff, J.R.2
-
21
-
-
0026723117
-
MRNAs containing extensive secondary structure in their 5 non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E
-
Koromilas, A. E., Lazaris-Karatzas, A. and Sonenberg, N. (1992) mRNAs containing extensive secondary structure in their 5 non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E. EMBO J. 11, 4153-4158
-
(1992)
EMBO J.
, vol.11
, pp. 4153-4158
-
-
Koromilas, A.E.1
Lazaris-Karatzas, A.2
Sonenberg, N.3
-
22
-
-
0027365517
-
Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E
-
Rosenwald, I. B., Lazaris-Karatzas, A., Sonenberg, N. and Schmidt, E. V. (1993) Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E. Mol. Cell. Biol. 13, 7358-7363 (Pubitemid 23354259)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.12
, pp. 7358-7363
-
-
Rosenwald, I.B.1
Lazaris-Karatzas, A.2
Sonenberg, N.3
Schmidt, E.V.4
-
23
-
-
0030041884
-
Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E
-
DOI 10.1073/pnas.93.3.1065
-
Rousseau, D., Kaspar, R., Rosenwald, I., Gehrke, L. and Sonenberg, N. (1996) Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. Proc. Natl. Acad. Sci. U.S.A. 93, 1065-1070 (Pubitemid 26054368)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.3
, pp. 1065-1070
-
-
Rousseau, D.1
Kaspar, R.2
Rosenwald, I.3
Gehrke, L.4
Sonenberg, N.5
-
24
-
-
0031800113
-
Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to eIF-4E
-
Scott, P. A., Smith, K., Poulsom, R., De Benedetti, A., Bicknell, R. and Harris, A. L. (1998) Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to eIF-4E. Br. J. Cancer. 77, 2120-2128 (Pubitemid 28263931)
-
(1998)
British Journal of Cancer
, vol.77
, Issue.12
, pp. 2120-2128
-
-
Scott, P.A.E.1
Smith, K.2
Poulsom, R.3
De Benedetti, A.4
Bicknell, R.5
Harris, A.L.6
-
25
-
-
9244228003
-
Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
-
DOI 10.1158/0008-5472.CAN-04-2677
-
Topisirovic, I., Ruiz-Gutierrez, M. and Borden, K. L. (2004) Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities. Cancer Res. 64, 8639-8642 (Pubitemid 39552077)
-
(2004)
Cancer Research
, vol.64
, Issue.23
, pp. 8639-8642
-
-
Topisirovic, I.1
Ruiz-Gutierrez, M.2
Borden, K.L.B.3
-
26
-
-
37249042829
-
Dissecting eIF4E action in tumorigenesis
-
DOI 10.1101/gad.1604407
-
Wendel, H. G., Silva, R. L., Malina, A., Mills, J. R., Zhu, H., Ueda, T., Watanabe-Fukunaga, R., Fukunaga, R., Teruya-Feldstein, J., Pelletier, J. and Lowe, S. W. (2007) Dissecting eIF4E action in tumorigenesis. Genes Dev. 21, 3232-3237 (Pubitemid 350277750)
-
(2007)
Genes and Development
, vol.21
, Issue.24
, pp. 3232-3237
-
-
Wendel, H.-G.1
Silva, R.L.A.2
Malina, A.3
Mills, J.R.4
Zhu, H.5
Ueda, T.6
Watanabe-Fukunaga, R.7
Fukunaga, R.8
Teruya-Feldstein, J.9
Pelletier, J.10
Lowe, S.W.11
-
27
-
-
77956275419
-
EIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
-
Furic, L., Rong, L., Larsson, O., Koumakpayi, I. H., Yoshida, K., Brueschke, A., Petroulakis, E., Robichaud, N., Pollak, M., Gaboury, L. A. et al. (2010) eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression. Proc. Natl. Acad. Sci. U.S.A. 107, 14134-14139
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 14134-14139
-
-
Furic, L.1
Rong, L.2
Larsson, O.3
Koumakpayi, I.H.4
Yoshida, K.5
Brueschke, A.6
Petroulakis, E.7
Robichaud, N.8
Pollak, M.9
Gaboury, L.A.10
-
28
-
-
84871920117
-
Inhibition of the interaction between NS3 protease and HCV IRES with a small peptide: A novel therapeutic strategy
-
Ray, U., Roy, C. L., Kumar, A., Mani, P., Joseph, A. P., Sudha, G., Sarkar, D. P., Srinivasan, N. and Das, S. (2012) Inhibition of the interaction between NS3 protease and HCV IRES with a small peptide: a novel therapeutic strategy. Mol. Ther. 21, 57-67
-
(2012)
Mol. Ther.
, vol.21
, pp. 57-67
-
-
Ray, U.1
Roy, C.L.2
Kumar, A.3
Mani, P.4
Joseph, A.P.5
Sudha, G.6
Sarkar, D.P.7
Srinivasan, N.8
Das, S.9
-
29
-
-
23044437222
-
Virology: Complete replication of hepatitis C virus in cell culture
-
DOI 10.1126/science.1114016
-
Lindenbach, B. D., Evans, M. J., Syder, A. J., Wolk, B., Tellinghuisen, T. L., Liu, C. C., Maruyama, T., Hynes, R. O., Burton, D. R., McKeating, J. A. and Rice, C. M. (2005) Complete replication of hepatitis C virus in cell culture. Science 309, 623-626 (Pubitemid 41033648)
-
(2005)
Science
, vol.309
, Issue.5734
, pp. 623-626
-
-
Lindenbach, B.D.1
Evans, M.J.2
Syder, A.J.3
Wolk, B.4
Tellinghuisen, T.L.5
Liu, C.C.6
Maruyama, T.7
Hynes, R.O.8
Burton, D.R.9
McKeating, J.A.10
Rice, C.M.11
-
30
-
-
79953187584
-
Purification of ribosomes from human cell lines
-
3.40:3.40.3.40:3.40.11
-
Belin, S., Hacot, S., Daudignon, L., Therizols, G., Pourpe, S., Mertani, H. C., Rosa-Calatrava, M. and Diaz, J. J. (2010) Purification of ribosomes from human cell lines. Curr. Protoc. Cell Biol., 49:3.40:3.40.1-49:3.40:3.40.11
-
(2010)
Curr. Protoc. Cell Biol.
, vol.49
, pp. 1-49
-
-
Belin, S.1
Hacot, S.2
Daudignon, L.3
Therizols, G.4
Pourpe, S.5
Mertani, H.C.6
Rosa-Calatrava, M.7
Diaz, J.J.8
-
31
-
-
77957852191
-
Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction
-
Shveygert, M., Kaiser, C., Bradrick, S. S. and Gromeier, M. (2010) Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction. Mol. Cell. Biol. 30, 5160-5167
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 5160-5167
-
-
Shveygert, M.1
Kaiser, C.2
Bradrick, S.S.3
Gromeier, M.4
-
32
-
-
0033521535
-
Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E
-
DOI 10.1093/emboj/18.1.270
-
Pyronnet, S., Imataka, H., Gingras, A. C., Fukunaga, R., Hunter, T. and Sonenberg, N. (1999) Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E. EMBO J. 18, 270-279 (Pubitemid 29005042)
-
(1999)
EMBO Journal
, vol.18
, Issue.1
, pp. 270-279
-
-
Pyronnet, S.1
Imataka, H.2
Gingras, A.-C.3
Fukunaga, R.4
Hunter, T.5
Sonenberg, N.6
-
33
-
-
0015009391
-
Dissociation of mammalian polyribosomes into subunits by puromycin
-
Blobel, G. and Sabatini, D. (1971) Dissociation of mammalian polyribosomes into subunits by puromycin. Proc. Natl. Acad. Sci. U.S.A. 68, 390-394
-
(1971)
Proc. Natl. Acad. Sci. U.S.A.
, vol.68
, pp. 390-394
-
-
Blobel, G.1
Sabatini, D.2
-
34
-
-
84861570717
-
A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production
-
Khachatoorian, R., Arumugaswami, V., Ruchala, P., Raychaudhuri, S., Maloney, E. M., Miao, E., Dasgupta, A. and French, S. W. (2012) A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production. Hepatology 55, 1662-1672
-
(2012)
Hepatology
, vol.55
, pp. 1662-1672
-
-
Khachatoorian, R.1
Arumugaswami, V.2
Ruchala, P.3
Raychaudhuri, S.4
Maloney, E.M.5
Miao, E.6
Dasgupta, A.7
French, S.W.8
-
35
-
-
7044228006
-
The pathway of HCV IRES-mediated translation initiation
-
DOI 10.1016/j.cell.2004.09.038, PII S0092867404008918
-
Otto, G. A. and Puglisi, J. D. (2004) The pathway of HCV IRES-mediated translation initiation. Cell 119, 369-380 (Pubitemid 39423839)
-
(2004)
Cell
, vol.119
, Issue.3
, pp. 369-380
-
-
Otto, G.A.1
Puglisi, J.D.2
-
36
-
-
0029422016
-
Translation of hepatitis C virus genome
-
Ali, N., Wang, C. and Siddiqui, A. (1995) Translation of hepatitis C virus genome. Princess Takamatsu Symp. 25, 99-110
-
(1995)
Princess Takamatsu Symp.
, vol.25
, pp. 99-110
-
-
Ali, N.1
Wang, C.2
Siddiqui, A.3
-
37
-
-
0026513651
-
Internal ribosome entry site within hepatitis C virus RNA
-
Tsukiyama-Kohara, K., Iizuka, N., Kohara, M. and Nomoto, A. (1992) Internal ribosome entry site within hepatitis C virus RNA. J. Virol. 66, 1476-1483
-
(1992)
J. Virol.
, vol.66
, pp. 1476-1483
-
-
Tsukiyama-Kohara, K.1
Iizuka, N.2
Kohara, M.3
Nomoto, A.4
-
38
-
-
33845623845
-
Structural and mechanistic insights into hepatitis C viral translation initiation
-
DOI 10.1038/nrmicro1558, PII NRMICRO1558
-
Fraser, C. S. and Doudna, J. A. (2007) Structural and mechanistic insights into hepatitis C viral translation initiation. Nat. Rev. Microbiol. 5, 29-38 (Pubitemid 44942301)
-
(2007)
Nature Reviews Microbiology
, vol.5
, Issue.1
, pp. 29-38
-
-
Fraser, C.S.1
Doudna, J.A.2
|