Predictive value of lactate in unselected critically ill patients: An analysis using fractional polynomials

Journal of Thoracic Disease

Volumn 6, Issue 7, 2014, Pages 995-1003

  Zhang, Zhongheng ^a   Chen, Kun ^a   Ni, Hongying ^a   Fan, Haozhe ^a  

^a ZHEJIANG NORMAL UNIVERSITY   (China)

Author keywords

Critically ill; Fractional polynomial; Intensive care unit (ICU); Lactate normalization; Mortality

Indexed keywords

LACTIC ACID;

ADULT; ARTICLE; COMORBIDITY; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DEMOGRAPHY; DISEASE ASSOCIATION; FEMALE; HUMAN; LABORATORY DIAGNOSIS; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MORTALITY; PREDICTIVE VALUE; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; RISK ASSESSMENT; RISK REDUCTION; SURVIVOR;

EID: 84905916899     PISSN: 20721439     EISSN: 20776624     Source Type: Journal    
DOI: 10.3978/j.issn.2072-1439.2014.07.01     Document Type: Article

References (26)

1. Fall PJ, Szerlip HM. Lactic acidosis: from sour milk to septic shock. J Intensive Care Med 2005;20:255-71.
2. Okorie ON, Dellinger P. Lactate: biomarker and potential therapeutic target. Crit Care Clin 2011;27:299-326.
3. Vecchio S, Giampreti A, Petrolini VM, et al. Metformin accumulation: lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66patients on chronic therapy. Clin Toxicol (Phila) 2014;52:129-35.
4. Gjedsted J, Buhl M, Nielsen S, et al. Effects of adrenaline on lactate, glucose, lipid and protein metabolism in the placebo controlled bilaterally perfused human leg. Acta Physiol (Oxf) 2011;202:641-8.
5. Fuller BM, Dellinger RP. Lactate as a hemodynamic marker in the critically ill. Curr Opin Crit Care 2012;18:267-72.
6. Gunnerson KJ, Saul M, He S, et al. Lactate versus nonlactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients. Crit Care 2006;10:R22.
7. Abramson D, Scalea TM, Hitchcock R, et al. Lactate clearance and survival following injury. J Trauma 1993;35:584-8; discussion 588-9.
8. Lee TR, Kang MJ, Cha WC, et al. Better lactate clearance associated with good neurologic outcome in survivors who treated with therapeutic hypothermia after out-of-hospital cardiac arrest. Crit Care 2013;17:R260.
9. Puskarich MA, Trzeciak S, Shapiro NI, et al. Whole blood lactate kinetics in patients undergoing quantitative resuscitation for severe sepsis and septic shock. Chest 2013;143:1548-53.
10. Liu XW, Ma T, Qu B, et al. Prognostic value of initial arterial lactate level and lactate metabolic clearance rate in patients with acute paraquat poisoning. Am J Emerg Med 2013;31:1230-5.
11. Saeed M, Villarroel M, Reisner AT, et al. Multiparameter Intelligent Monitoring in Intensive Care II: a public-access intensive care unit database. Crit Care Med 2011;39:952-60.
12. Scott DJ, Lee J, Silva I, et al. Accessing the public MIMICII intensive care relational database for clinical research. BMC Med Inform Decis Mak 2013;13:9.
13. Bursac Z, Gauss CH, Williams DK, et al. Purposeful selection of variables in logistic regression. Source Code Biol Med 2008;3:17.
14. Royston P, Altman DG. Regression Using Fractional Polynomials of Continuous Covariates: Parsimonious Parametric Modelling. Appl Stat 1994;43:429-67.
15. Sauerbrei W, Meier-Hirmer C, Benner A, et al. Multivariable regression model building by using fractional polynomials: Description of SAS, STATA and R programs. Computational Statistics and Data Analysis 2006;50:3464-85.
16. Marty P, Roquilly A, Vallée F, et al. Lactate clearance for death prediction in severe sepsis or septic shock patients during the first 24 hours inIntensive Care Unit: an observational study. Ann Intensive Care 2013;3:3.
17. Murtuza B, Wall D, Reinhardt Z, et al. The importance of blood lactate clearance as a predictor of early mortality following the modified Norwoodprocedure. Eur J Cardiothorac Surg 2011;40:1207-14.
18. Borthwick HA, Brunt LK, Mitchem KL, et al. Does lactate measurement performed on admission predict clinical outcome on the intensive care unit? A concisesystematic review. Ann Clin Biochem 2012;49:391-4.
19. Maarslet L, Møller MB, Dall R, et al. Lactate levels predict mortality and need for peritoneal dialysis in children undergoing congenital heart surgery. Acta Anaesthesiol Scand 2012;56:459-64.
20. Hajjar LA, Almeida JP, Fukushima JT, et al. High lactate levels are predictors of major complications after cardiac surgery. J Thorac Cardiovasc Surg 2013;146:455-60.
21. Badreldin AM, Doerr F, Elsobky S, et al. Mortality prediction after cardiac surgery: blood lactate is indispensible. Thorac Cardiovasc Surg 2013;61:708-17.
22. Altman DG, Bland JM. Time to event (survival) data. BMJ 1998;317:468-9.
23. Schmidt CO, Ittermann T, Schulz A, et al. Linear, nonlinear or categorical: how to treat complex associations in regression analyses? Polynomialtransformations and fractional polynomials. Int J Public Health 2013;58:157-60.
24. Husain FA, Martin MJ, Mullenix PS, et al. Serum lactate and base deficit as predictors of mortality and morbidity. Am J Surg 2003;185:485-91.
25. McNelis J, Marini CP, Jurkiewicz A, et al. Prolonged lactate clearance is associated with increased mortality in the surgical intensive care unit. Am J Surg 2001;182:481-5.
26. Arnold RC, Shapiro NI, Jones AE, et al. Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis. Shock 2009;32:35-9.