-
1
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss RS, Karl IE: The pathophysiology and treatment of sepsis. N Engl J Med 348:138-150, 2003.
-
(2003)
N Engl J Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
2
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368-1377, 2001.
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
Ressler, J.4
Muzzin, A.5
Knoblich, B.6
Peterson, E.7
Tomlanovich, M.8
-
3
-
-
54549122745
-
The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: A meta-analysis
-
Jones AE, Brown MD, Trzeciak S, Shapiro NI, Garrett JS, Heffner AC, Kline JA: The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: a meta-analysis. Crit Care Med 36:2734-2739, 2008.
-
(2008)
Crit Care Med
, vol.36
, pp. 2734-2739
-
-
Jones, A.E.1
Brown, M.D.2
Trzeciak, S.3
Shapiro, N.I.4
Garrett, J.S.5
Heffner, A.C.6
Kline, J.A.7
-
4
-
-
37549020378
-
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
-
Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, et al.: Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 36:296-327, 2008.
-
(2008)
Crit Care Med
, vol.36
, pp. 296-327
-
-
Dellinger, R.P.1
Levy, M.M.2
Carlet, J.M.3
Bion, J.4
Parker, M.M.5
Jaeschke, R.6
Reinhart, K.7
Angus, D.C.8
Brun-Buisson, C.9
Beale, R.10
-
5
-
-
34247551158
-
The incidence and outcome of septic shock patients in the absence of early-goal directed therapy
-
Ho BC, Bellomo R, McGain F, Jones D, Naka T, Wan L, Braitberg G: The incidence and outcome of septic shock patients in the absence of early-goal directed therapy. Crit Care 10:R80, 2006.
-
(2006)
Crit Care
, vol.10
-
-
Ho, B.C.1
Bellomo, R.2
McGain, F.3
Jones, D.4
Naka, T.5
Wan, L.6
Braitberg, G.7
-
6
-
-
33947161625
-
Early goal-directed therapy of septic shock: We honestly remain skeptical
-
Peake S, Webb S, Delaney A: Early goal-directed therapy of septic shock: we honestly remain skeptical. Crit Care Med 35:994-995, 2007.
-
(2007)
Crit Care Med
, vol.35
, pp. 994-995
-
-
Peake, S.1
Webb, S.2
Delaney, A.3
-
7
-
-
35448971112
-
Occult hypoperfusion and mortality in patients with suspected infection
-
Howell MD, Donnino M, Clardy P, Talmor D, Shapiro NI: Occult hypoperfusion and mortality in patients with suspected infection. Intensive Care Med 33:1892-1899, 2007.
-
(2007)
Intensive Care Med
, vol.33
, pp. 1892-1899
-
-
Howell, M.D.1
Donnino, M.2
Clardy, P.3
Talmor, D.4
Shapiro, N.I.5
-
8
-
-
17844398255
-
Serum lactate as a predictor of mortality in emergency department patients with infection
-
Shapiro NI, Howell MD, Talmor D, Nathanson LA, Lisbon A, Wolfe RE, Weiss JW: Serum lactate as a predictor of mortality in emergency department patients with infection. Ann Emerg Med 45:524-528, 2005.
-
(2005)
Ann Emerg Med
, vol.45
, pp. 524-528
-
-
Shapiro, N.I.1
Howell, M.D.2
Talmor, D.3
Nathanson, L.A.4
Lisbon, A.5
Wolfe, R.E.6
Weiss, J.W.7
-
9
-
-
34249739559
-
Serum lactate as a predictor of mortality in patients with infection
-
Trzeciak S, Dellinger RP, Chansky ME, Arnold RC, Schorr C, Milcarek B, Hollenberg SM, Parrillo JE: Serum lactate as a predictor of mortality in patients with infection. Intensive Care Med 33:970-977, 2007.
-
(2007)
Intensive Care Med
, vol.33
, pp. 970-977
-
-
Trzeciak, S.1
Dellinger, R.P.2
Chansky, M.E.3
Arnold, R.C.4
Schorr, C.5
Milcarek, B.6
Hollenberg, S.M.7
Parrillo, J.E.8
-
10
-
-
0025735897
-
Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock
-
Bakker J, Coffernils M, Leon M, Gris P, Vincent JL: Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock. Chest 99:956-962, 1991.
-
(1991)
Chest
, vol.99
, pp. 956-962
-
-
Bakker, J.1
Coffernils, M.2
Leon, M.3
Gris, P.4
Vincent, J.L.5
-
11
-
-
0030024779
-
Serial blood lactate levels can predict the development of multiple organ failure following septic shock
-
Bakker J, Gris P, Coffernils M, Kahn RJ, Vincent JL: Serial blood lactate levels can predict the development of multiple organ failure following septic shock. Am J Surg 171:221-226, 1996.
-
(1996)
Am J Surg
, vol.171
, pp. 221-226
-
-
Bakker, J.1
Gris, P.2
Coffernils, M.3
Kahn, R.J.4
Vincent, J.L.5
-
12
-
-
3943052086
-
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock
-
Nguyen HB, Rivers EP, Knoblich BP, Jacobsen G, Muzzin A, Ressler JA, Tomlanovich MC: Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med 32:1637-1642, 2004.
-
(2004)
Crit Care Med
, vol.32
, pp. 1637-1642
-
-
Nguyen, H.B.1
Rivers, E.P.2
Knoblich, B.P.3
Jacobsen, G.4
Muzzin, A.5
Ressler, J.A.6
Tomlanovich, M.C.7
-
13
-
-
67749125763
-
-
EMSHOCKNET, Available at:, Accessed: November, 2008
-
EMSHOCKNET. Emergency Medicine Shock Research Network. Available at: www.emshocknet.com. Accessed: November, 2008.
-
Emergency Medicine Shock Research Network
-
-
-
14
-
-
34548018339
-
Prospective external validation of the clinical effectiveness of an emergency department-based early goaldirected therapy protocol for severe sepsis and septic shock
-
Jones AE, Focht A, Horton JM, Kline JA: Prospective external validation of the clinical effectiveness of an emergency department-based early goaldirected therapy protocol for severe sepsis and septic shock. Chest 132(2): 425-432, 2007.
-
(2007)
Chest
, vol.132
, Issue.2
, pp. 425-432
-
-
Jones, A.E.1
Focht, A.2
Horton, J.M.3
Kline, J.A.4
-
15
-
-
33645805899
-
Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol
-
Shapiro NI, Howell MD, Talmor D, Lahey D, Ngo L, Buras J, Wolfe RE, Weiss JW, Lisbon A: Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol. Crit Care Med 34(4): 1025-1032, 2006.
-
(2006)
Crit Care Med
, vol.34
, Issue.4
, pp. 1025-1032
-
-
Shapiro, N.I.1
Howell, M.D.2
Talmor, D.3
Lahey, D.4
Ngo, L.5
Buras, J.6
Wolfe, R.E.7
Weiss, J.W.8
Lisbon, A.9
-
16
-
-
33344468985
-
Translating research to clinical practice: A 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department
-
Trzeciak S, Dellinger RP, Abate NL, Cowan RM, Stauss M, Kilgannon JH, Zanotti S, Parrillo JE: Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department. Chest 129:225-232, 2006.
-
(2006)
Chest
, vol.129
, pp. 225-232
-
-
Trzeciak, S.1
Dellinger, R.P.2
Abate, N.L.3
Cowan, R.M.4
Stauss, M.5
Kilgannon, J.H.6
Zanotti, S.7
Parrillo, J.E.8
-
17
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
-
Chest
-
Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101:1644-1655, 1992.
-
(1992)
The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
Dellinger, R.P.4
Fein, A.M.5
Knaus, W.A.6
Schein, R.M.7
Sibbald, W.J.8
-
19
-
-
0030015661
-
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine
-
Vincent JL, Moreno R, Takala J, Willatts S, De Mendonca A, Bruining H, Reinhart CK, Suter PM, Thijs LG: The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 22:707-710, 1996.
-
(1996)
Intensive Care Med
, vol.22
, pp. 707-710
-
-
Vincent, J.L.1
Moreno, R.2
Takala, J.3
Willatts, S.4
De Mendonca, A.5
Bruining, H.6
Reinhart, C.K.7
Suter, P.M.8
Thijs, L.G.9
-
20
-
-
0037352375
-
Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial
-
Vincent JL, Angus DC, Artigas A, Kalil A, Basson BR, Jamal HH, Johnson G 3rd, Bernard GR: Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial. Crit Care Med 31:834-840, 2003.
-
(2003)
Crit Care Med
, vol.31
, pp. 834-840
-
-
Vincent, J.L.1
Angus, D.C.2
Artigas, A.3
Kalil, A.4
Basson, B.R.5
Jamal, H.H.6
Johnson 3rd, G.7
Bernard, G.R.8
-
21
-
-
0029613841
-
Importance of events per independent variable in proportional hazards regression analysis. II. Accuracy and precision of regression estimates
-
Peduzzi P, Concato J, Feinstein AR, Holford TR: Importance of events per independent variable in proportional hazards regression analysis. II. Accuracy and precision of regression estimates. J Clin Epidemiol 48: 1503-1510, 1995.
-
(1995)
J Clin Epidemiol
, vol.48
, pp. 1503-1510
-
-
Peduzzi, P.1
Concato, J.2
Feinstein, A.R.3
Holford, T.R.4
-
22
-
-
0030474271
-
A simulation study of the number of events per variable in logistic regression analysis
-
Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR: A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol 49:1373-1379, 1996.
-
(1996)
J Clin Epidemiol
, vol.49
, pp. 1373-1379
-
-
Peduzzi, P.1
Concato, J.2
Kemper, E.3
Holford, T.R.4
Feinstein, A.R.5
-
23
-
-
33750035147
-
Emergency department hypotension predicts sudden unexpected in-hospital mortality: A prospective cohort study
-
Jones AE, Yiannibas V, Johnson C, Kline JA: Emergency department hypotension predicts sudden unexpected in-hospital mortality: a prospective cohort study. Chest 130:941-946, 2006.
-
(2006)
Chest
, vol.130
, pp. 941-946
-
-
Jones, A.E.1
Yiannibas, V.2
Johnson, C.3
Kline, J.A.4
-
24
-
-
0026629446
-
Role of tissue hypoxia as the mechanism of lactic acidosis during E. coli endotoxemia
-
Hurtado FJ, Gutierrez AM, Silva N, Fernandez E, Khan AE, Gutierrez G: Role of tissue hypoxia as the mechanism of lactic acidosis during E. coli endotoxemia. J Appl Physiol 72:1895-1901, 1992.
-
(1992)
J Appl Physiol
, vol.72
, pp. 1895-1901
-
-
Hurtado, F.J.1
Gutierrez, A.M.2
Silva, N.3
Fernandez, E.4
Khan, A.E.5
Gutierrez, G.6
-
25
-
-
0030203145
-
Sepsis-induced alterations in pyruvate dehydrogenase complex activity in rat skeletal muscle: Effects on plasma lactate
-
Vary TC: Sepsis-induced alterations in pyruvate dehydrogenase complex activity in rat skeletal muscle: effects on plasma lactate. Shock 6:89-94, 1996.
-
(1996)
Shock
, vol.6
, pp. 89-94
-
-
Vary, T.C.1
-
26
-
-
0033533116
-
Lactate is an unreliable indicator of tissue hypoxia in injury or sepsis
-
James JH, Luchette FA, McCarter FD, Fischer JE: Lactate is an unreliable indicator of tissue hypoxia in injury or sepsis. Lancet 354:505-508, 1999.
-
(1999)
Lancet
, vol.354
, pp. 505-508
-
-
James, J.H.1
Luchette, F.A.2
McCarter, F.D.3
Fischer, J.E.4
-
27
-
-
0036123381
-
Hypoxia is not the sole cause of lactate production during shock
-
Luchette FA, Jenkins WA, Friend LA, Su C, Fischer JE, James JH: Hypoxia is not the sole cause of lactate production during shock. J Trauma 52:415-419, 2002.
-
(2002)
J Trauma
, vol.52
, pp. 415-419
-
-
Luchette, F.A.1
Jenkins, W.A.2
Friend, L.A.3
Su, C.4
Fischer, J.E.5
James, J.H.6
-
28
-
-
0037040572
-
Role of skeletal muscle Na+-K+ ATPase activity in increased lactate production in sub-acute sepsis
-
McCarter FD, Nierman SR, James JH, Wang L, King JK, Friend LA, Fischer JE: Role of skeletal muscle Na+-K+ ATPase activity in increased lactate production in sub-acute sepsis. Life Sci 70:1875-1888, 2002.
-
(2002)
Life Sci
, vol.70
, pp. 1875-1888
-
-
McCarter, F.D.1
Nierman, S.R.2
James, J.H.3
Wang, L.4
King, J.K.5
Friend, L.A.6
Fischer, J.E.7
-
29
-
-
0031968240
-
Mild hyperlactatemia in stable septic patients is due to impaired lactate clearance rather than overproduction
-
Levraut J, Ciebiera JP, Chave S, Rabary O, Jambou P, Carles M, Grimaud D: Mild hyperlactatemia in stable septic patients is due to impaired lactate clearance rather than overproduction. Am J Respir Crit Care Med 157: 1021-1026, 1998.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1021-1026
-
-
Levraut, J.1
Ciebiera, J.P.2
Chave, S.3
Rabary, O.4
Jambou, P.5
Carles, M.6
Grimaud, D.7
-
30
-
-
0029583745
-
Liver injury during sepsis
-
Pastor CM, Billiar TR, Losser MR, Payen DM: Liver injury during sepsis. J Crit Care 10:183-197, 1995.
-
(1995)
J Crit Care
, vol.10
, pp. 183-197
-
-
Pastor, C.M.1
Billiar, T.R.2
Losser, M.R.3
Payen, D.M.4
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