Prolonged lactate clearance is associated with increased mortality in the surgical intensive care unit

American Journal of Surgery

Volumn 182, Issue 5, 2001, Pages 481-485

  McNelis, John ^a,b   Marini, Corrado P ^a   Jurkiewicz, Antoni ^a   Szomstein, Samuel ^a   Simms, H Hank ^a   Ritter, Garry ^a   Nathan, Ira M ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b LONG ISLAND JEWISH MEDICAL CENTER   (United States)

Author keywords

Intensive care unit mortality; Lactate; Lactate clearance; Oxygen delivery; Resuscitation; Surgical intensive care unit

Indexed keywords

LACTIC ACID;

ADULT; AGED; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; DATA ANALYSIS; DEMOGRAPHY; DISEASE ASSOCIATION; FEMALE; HEMODYNAMIC MONITORING; HOSPITAL DEPARTMENT; HUMAN; INTENSIVE CARE; LABORATORY TEST; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE ANALYSIS; POSTOPERATIVE CARE; PREDICTION; PRIORITY JOURNAL; SURVIVAL RATE; TREATMENT OUTCOME;

AGED; APACHE; CRITICAL ILLNESS; ENDPOINT DETERMINATION; HUMANS; INTENSIVE CARE; INTENSIVE CARE UNITS; LACTIC ACID; MULTIVARIATE ANALYSIS; POSTOPERATIVE CARE; RESUSCITATION; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 0035688766     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9610(01)00755-3     Document Type: Article

References (19)

1. Blood lactate levels are better prognostic indicators than TNF and IL-6 levels in patients with septic shock
2. Lactate clearance and survival following injury
3. Serial blood lactate levels can predict the developement of multiple organ failure following septic shock
4. Lactic acidosis during sepsis is related to increased pyruvate production not defects in tissue oxygen availability
5. Evidence for early supply independent mitochondrial dysfunction in patients developing multiple organ failure after trauma
6. Prospective, randomized trial of survivor values of cardiac index, oxygen delivery, and oxygen consumption as endpoints in severe trauma
7. A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high risk surgical patients
8. Prospective trial of supranormal values of survivors as theraputic goals in high risk surgical patients
9. Serum cytokine levels in human septic shock: Relation to multiple system organ failure and mortality
10. Oxygen transport patterns in patients with sepsis syndrome or septic shock: Influence of treatment and relationship to outcome
11. Oxygen transport dependant splanchnic metabolism in the sepsis syndrome
12. Peripheral oxygen availability within skeletal muscle in sepsis and septic shock: Comparison to limited infection and cardiogenic shock
13. Combined measurements of blood lactate levels and gastric intramucosal pH in patients with severe sepsis
14. Serial lactate determinations during circulatory shock
15. Experimental and clinical studies on lactate and pyruvate as indicators of the severity of acute circulatory failure
16. The relationship between oxygen delivery and oxygenconsumption during fluid resuscitation of burn-related shock
17. The use of oxygen consumption and delivery as endpoints for resuscitation in critically ill patients
18. The relationship between oxygen delivery and uptake in the critically ill: Is there a critical or optimal theraputic value? A meta analysis
19. Oxygen delivery in patients with adult respiratory distress syndrome who undergo surgery: Correlation with multiple system organ failure