Isolated spinal cord contusion in rats induces chronic brain neuroinflammation, neurodegeneration,and cognitive impairment: Involvement of cell cycle activation

Cell Cycle

Volumn 13, Issue 15, 2014, Pages 2446-2458

  Wu, Junfang ^a   Stoica, Bogdan A ^a   Luo, Tao ^a   Sabirzhanov, Boris ^a   Zhao, Zaorui ^a   Guanciale, Kelsey ^a   Nayar, Suresh K ^b   Foss, Catherine A ^b   Pomper, Martin G ^b   Faden, Alan I ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brain; Cell cycle activation; Cognitive impairment; Inflammation; Neurodegeneration; Spinal cord injury

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; SECONDARY LYMPHOID TISSUE CHEMOKINE; BIOLOGICAL MARKER; CELL CYCLE PROTEIN; CR8 COMPOUND; CYCLIN DEPENDENT KINASE; PROTEIN KINASE INHIBITOR; PURINE DERIVATIVE; PYRIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; COGNITIVE DEFECT; EXPERIMENTAL SPINAL CORD CONTUSION; HIPPOCAMPUS; HYPERESTHESIA; IMMUNOHISTOCHEMISTRY; MAZE TEST; MICROGLIA; MOTOR DYSFUNCTION; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PASSIVE AVOIDANCE TEST; RAT; STEREOMETRY; THALAMUS; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; CELL CYCLE; CHRONIC DISEASE; COGNITION DISORDERS; COMPLICATION; ENZYMOLOGY; MALE; METABOLISM; MILD COGNITIVE IMPAIRMENT; NEURODEGENERATIVE DISEASES; PATHOLOGY; PATHOPHYSIOLOGY; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT;

ANIMALS; BIOMARKERS; BRAIN; CELL CYCLE; CELL CYCLE PROTEINS; CHEMOKINE CCL21; CHRONIC DISEASE; COGNITION DISORDERS; CYCLIN-DEPENDENT KINASES; MALE; MICROGLIA; MILD COGNITIVE IMPAIRMENT; NERVE DEGENERATION; NEURODEGENERATIVE DISEASES; PROTEIN KINASE INHIBITORS; PURINES; PYRIDINES; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES;

EID: 84905913374     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.29420     Document Type: Article

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