MicroRNA-543 suppresses endometrial cancer oncogenicity via targeting FAK and TWIST1 expression

Archives of Gynecology and Obstetrics

Volumn 290, Issue 3, 2014, Pages 533-541

  Li, Bing ^a   Chen, Hong ^a   Shang, Li Xin ^a   Gao, Wei ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b Chang Ping Maternal and Child Health Hospital   (China)

Author keywords

Endometrial cancer; FAK; MicroRNA 543; TWIST1

Indexed keywords

ADENOCARCINOMA; BLOTTING, WESTERN; CARCINOMA; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; ENDOMETRIAL NEOPLASMS; ENDOMETRIUM; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; NEOPLASM INVASIVENESS; NUCLEAR PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TWIST TRANSCRIPTION FACTOR;

EID: 84905909667     PISSN: 09320067     EISSN: 14320711     Source Type: Journal    
DOI: 10.1007/s00404-014-3219-3     Document Type: Article

References (30)

1. Mutz-Dehbalaie I, Egle D, Fessler S, Hubalek M, Fiegl H, Marth C, Widschwendter A (2012) HE4 is an independent prognostic marker in endometrial cancer patients. Gynecol Oncol 126(2):186-191. doi:10.1016/j.ygyno.2012.04.022
2. Amant F, Moerman P, Neven P, Timmerman D, Van Limbergen E, Vergote I (2005) Endometrial cancer. Lancet 366(9484):491-505. doi:10.1016/S0140-6736(05) 67063-8 (Pubitemid 41111699)
3. Kitchener H (2006) Management of endometrial cancer. Eur J Surg Oncol: J Eur Soc Surg Oncol Br Assoc Surg Oncol 32(8):838-843. doi:10.1016/j.ejso.2006. 03.046
4. Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136(2):215-233. doi:10.1016/j.cell.2009.01.002
5. Ma L, Teruya-Feldstein J, Weinberg RA (2007) Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449(7163):682-688. doi:10.1038/nature06174 (Pubitemid 47552092)
6. Poliseno L, Salmena L, Riccardi L, Fornari A, Song, Hobbs RM, Sportoletti P, Varmeh S, Egia A, Fedele G, Rameh L, Loda M, Pandolfi PP (2010) Identification of the miR-106b ∼ 25 micro-RNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci signal 3(117):ra29. doi:10.1126/scisignal.2000594
7. Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D, Teruya-Feldstein J, Reinhardt F, Onder TT, Valastyan S, Westermann F, Speleman F, Vandesompele J, Weinberg RA (2010) miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol 12(3):247-256. doi:10.1038/ncb2024
8. Tavazoie SF, Alarcon C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, Massague J (2008) Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451(7175):147-152. doi:10.1038/nature06487
9. Kyo S, Sakaguchi J, Ohno S, Mizumoto Y, Maida Y, Hashimoto M, Nakamura M, Takakura M, Nakajima M, Masutomi K, Inoue M (2006) High Twist expression is involved in infiltrative endometrial cancer and affects patient survival. Hum Pathol 37(4):431-438. doi:10.1016/j.humpath.2005.12.021
10. Livasy CA, Moore D, Cance WG, Lininger RA (2004) Focal adhesion kinase overexpression in endometrial neoplasia. Appl Immunohistochem Mol Morphol: AIMM/Off Publ Soc Appl Immunohistochem 12(4):342-345
11. Haga CL, Phinney DG (2012) MicroRNAs in the imprinted DLK1-DIO3 region repress the epithelial-to-mesenchymal transition by targeting the TWIST1 protein signaling network. J Biol Chem 287(51):42695-42707. doi:10.1074/jbc.M112.387761
12. Gupta GP, Massague J (2006) Cancer metastasis: building a framework. Cell 127(4):679-695. doi:10.1016/j.cell.2006.11.001 (Pubitemid 44781029)
13. Krek A, Grun D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, MacMenamin P, da Piedade I, Gunsalus KC, Stoffel M, Rajewsky N (2005) Combinatorial microRNA target predictions. Nat Genet 37(5):495-500. doi:10.1038/ng1536 (Pubitemid 40617277)
14. Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27(1):91-105. doi:10.1016/j.molcel.2007.06.017 (Pubitemid 46991392)
15. McLean GW, Carragher NO, Avizienyte E, Evans J, Brunton VG, Frame MC (2005) The role of focal-adhesion kinase in cancer - a new therapeutic opportunity. Nat Rev Cancer 5(7):505-515. doi:10.1038/nrc1647 (Pubitemid 40942827)
16. Schlaepfer DD, Hanks SK, Hunter T, van der Geer P (1994) Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372(6508):786-791
17. Cance WG, Harris JE, Iacocca MV, Roche E, Yang X, Chang J, Simkins S, Xu L (2000) Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes. Clin Cancer Res: Off J Am Assoc Cancer Res 6(6):2417-2423 (Pubitemid 30399210)
18. Gabriel B, Hasenburg A, Waizenegger M, Orlowska-Volk M, Stickeler E, zur Hausen A (2009) Expression of focal adhesion kinase in patients with endometrial cancer: a clinicopathologic study. Int J Gynecol Cancer: Off J Int Gynecol Cancer Soc 19(7):1221-1225. doi:10.1111/IGC.0b013e3181b33c61
19. Judson PL, He X, Cance WG, Van Le L (1999) Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma. Cancer 86(8):1551-1556 (Pubitemid 29489790)
20. Kornberg LJ (1998) Focal adhesion kinase expression in oral cancers. Head Neck 20(7):634-639
21. Kong X, Li G, Yuan Y, He Y, Wu X, Zhang W, Wu Z, Chen T, Wu W, Lobie PE, Zhu T (2012) MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression. PLoS One 7(8):e41523. doi:10.1371/journal.pone.0041523
22. Wu DG, Wang Y, Fan LG, Luo H, Han B, Sun LH, Wang XF, Zhang JX, Cao L, Wang XR, You YP, Liu N (2011) MicroRNA-7 regulates glioblastoma cell invasion via targeting focal adhesion kinase expression. Chin Med J 124(17):2616-2621
23. Ding J, Huang S, Wu S, Zhao Y, Liang L, Yan M, Ge C, Yao J, Chen T, Wan D, Wang H, Gu J, Yao M, Li J, Tu H, He X (2010) Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA. Nat Cell Biol 12(4):390-399. doi:10.1038/ncb2039
24. Castanon I, Baylies MK (2002) A Twist in fate: evolutionary comparison of Twist structure and function. Gene 287(1-2):11-22 (Pubitemid 34460565)
25. Maestro R, Dei Tos AP, Hamamori Y, Krasnokutsky S, Sartorelli V, Kedes L, Doglioni C, Beach DH, Hannon GJ (1999) Twist is a potential oncogene that inhibits apoptosis. Genes Dev 13(17):2207-2217 (Pubitemid 29426726)
26. Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A, Weinberg RA (2004) Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117(7):927-939. doi:10.1016/j.cell.2004.06.006 (Pubitemid 38798858)
27. Martin TA, Parr C, Davies G, Watkins G, Lane J, Matsumoto K, Nakamura T, Mansel RE, Jiang WG (2003) Growth and angiogenesis of human breast cancer in a nude mouse tumour model is reduced by NK4, a HGF/SF antagonist. Carcinogenesis 24(8):1317-1323. doi:10.1093/carcin/bgg072 (Pubitemid 37038821)
28. Rosivatz E, Becker I, Specht K, Fricke E, Luber B, Busch R, Hofler H, Becker KF (2002) Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer. Am J Pathol 161(5):1881-1891. doi:10.1016/S0002-9440(10)64464-1 (Pubitemid 35265545)
29. Hagan JP, O'Neill BL, Stewart CL, Kozlov SV, Croce CM (2009) At least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1. PLoS One 4(2):e4352. doi:10.1371/journal.pone.0004352
30. Edwards CA, Mungall AJ, Matthews L, Ryder E, Gray DJ, Pask AJ, Shaw G, Graves JA, Rogers J, Dunham I, Renfree MB, Ferguson-Smith AC (2008) The evolution of the DLK1-DIO3 imprinted domain in mammals. PLoS Biol 6(6):e135. doi:10.1371/journal.pbio.0060135