MicroRNAs in the imprinted DLK1-DIO3 region repress the epithelial-to-mesenchymal transition by targeting the TWIST1 protein signaling network

Journal of Biological Chemistry

Volumn 287, Issue 51, 2012, Pages 42695-42707

  Haga, Christopher L ^a   Phinney, Donald G ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOMA CELLS; CARCINOMA PATIENTS; CELL CYCLE; CPG ISLANDS; CRITICAL STEPS; DIAGNOSTIC TOOLS; ECTOPIC EXPRESSIONS; EPIGENETIC MODIFICATION; EXPRESSION LEVELS; HYPERMETHYLATION; METASTATIC DISEASE; MICRORNAS; PROMOTER METHYLATION; PROTEIN SIGNALING; SIGNALING NETWORKS; THERAPEUTIC TARGETS; TUMOR CELL LINES; TUMOR GROWTH; TUMOR METASTASIS; TUMOR PROGRESSIONS;

ALKYLATION; CELL CULTURE; PATHOLOGY; RNA; SIGNALING;

TUMORS;

ATM PROTEIN; BMI1 PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICRORNA; MICRORNA 200; MICRORNA 300; MICRORNA 382; MICRORNA 494; MICRORNA 495; MICRORNA 539; MICRORNA 543; MICRORNA 544; PROTEIN KINASE B; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR SOX9; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST 1; TRANSCRIPTION FACTOR ZEB1; TRANSCRIPTION FACTOR ZEB2; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

3' UNTRANSLATED REGION; ARTICLE; CANCER CONTROL; CANCER INHIBITION; CANCER INVASION; CELL MOTILITY; CELL STRAIN HEK293; CELL STRUCTURE; CHROMOSOME 14; CONTROLLED STUDY; CPG ISLAND; DLK1 DIO3 IMPRINTED REGION; DNA METHYLATION; DNA MODIFICATION; DOWN REGULATION; EPIGENETICS; EPITHELIAL MESENCHYMAL TRANSITION; G1 PHASE CELL CYCLE CHECKPOINT; GAIN OF FUNCTION MUTATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; INTRACELLULAR SIGNALING; INTRADUCTAL CARCINOMA; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; METASTASIS INHIBITION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

BASE SEQUENCE; BREAST; BREAST NEOPLASMS; CADHERINS; CARCINOMA, DUCTAL, BREAST; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SHAPE; DNA-BINDING PROTEINS; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC LOCI; GENOMIC IMPRINTING; HUMANS; MICRORNAS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NEOPLASM INVASIVENESS; NUCLEAR PROTEINS; POLYCOMB REPRESSIVE COMPLEX 1; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; TWIST TRANSCRIPTION FACTOR;

EID: 84871118304     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.387761     Document Type: Article

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