Human selenium binding protein-1 (hSP56) is a negative regulator of HIF-1α and suppresses the malignant characteristics of prostate cancer cells

BMB Reports

Volumn 47, Issue 7, 2014, Pages 411-416

  Jeong, Jee Yeong ^a,b   Zhou, Jin Rong ^a   Gao, Chong ^a   Feldman, Laurie ^a   Sytkowski, Arthur J ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Kosin University College of Medicine   (South Korea)

^c IQVIA   (United States)

Author keywords

Hypoxia inducible factor; Prostate cancer; Protein protein interaction; pVHL interacting deubiquitinating enzyme; Selenium binding protein

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PROTEIN BINDING; SELENBP1 PROTEIN, HUMAN; SELENIUM BINDING PROTEIN; UBIQUITIN THIOLESTERASE; USP20 PROTEIN, HUMAN; USP33 PROTEIN, HUMAN;

ANIMAL; ANTAGONISTS AND INHIBITORS; CELL TRANSFORMATION; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; DOWN REGULATION; GENETICS; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; MALE; METABOLISM; MOUSE; PATHOLOGY; PROSTATE TUMOR; RNA INTERFERENCE; SCID MOUSE; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CERCOPITHECUS AETHIOPS; COS CELLS; DOWN-REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; MICE; MICE, INBRED ICR; MICE, SCID; PROSTATIC NEOPLASMS; PROTEIN BINDING; RNA INTERFERENCE; RNA, MESSENGER; SELENIUM-BINDING PROTEINS; TRANSPLANTATION, HETEROLOGOUS; UBIQUITIN THIOLESTERASE;

EID: 84905906253     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2014.47.7.104     Document Type: Article

References (31)

1. Yang, M. and Sytkowski, A. J. (1998) Differential expression and androgen regulation of the human selenium- binding protein gene hSP56 in prostate cancer cells. Cancer Res. 58, 3150-3153.
2. Chang, P. W., Tsui, S. K., Liew, C., Lee, C. C., Waye, M. M. and Fung, K. P. (1997) Isolation, characterization, and chromosomal mapping of a novel cDNA clone encoding human selenium binding protein. J. Cell Biochem. 64, 217-224.
3. Wu, C. L., Zhang, W. B., Mai, K. S., Liang, X. F., Xu, W., Wang, J. and Ma, H. M. (2010) Molecular cloning, characterization and mRNA expression of selenium-binding protein in abalone (Haliotis discus hannai Ino): Response to dietary selenium, iron and zinc. Fish Shellfish Immunol. 29, 117-125.
4. Chen, G., Wang, H., Miller, C. T., Thomas, D. G., Gharib, T. G., Misek, D. E., Giordano, T. J., Orringer, M. B., Hanash, S. M. and Beer, D. G. (2004) Reduced selenium- binding protein 1 expression is associated with poor outcome in lung adenocarcinomas. J. Pathol. 202, 321-329.
5. Brown, L. M., Helmke, S. M., Hunsucker, S. W., Netea-Maier, R. T., Chiang, S. A., Heinz, D. E., Shroyer, K. R., Duncan, M. W. and Haugen, B. R. (2006) Quantitative and qualitative differences in protein expression between papillary thyroid carcinoma and normal thyroid tissue. Mol. Carcinog. 45, 613-626.
6. Kim, H., Kang, H. J., You, K. T., Kim, S. H., Lee, K. Y., Kim, T. I., Kim, C., Song, S. Y., Kim, H. J. and Lee, C. (2006) Suppression of human selenium-binding protein 1 is a late event in colorectal carcinogenesis and is associated with poor survival. Proteomics 6, 3466-3476.
7. Li, T., Yang, W., Li, M., Byun, D. S., Tong, C., Nasser, S., Zhuang, M., Arango, D., Mariadason, J. M. and Augenlicht, L. H. (2008) Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer. Mol. Nutr. Food Res. 52, 1289-1299.
8. Zhang, P., Zhang, C., Wang, X., Liu, F., Sung, C. J., Quddus, M. R. and Lawrence, W. D. (2011) The expression of selenium-binding protein 1 is decreased in uterine leiomyoma. Diagn. Pathol. 5, 80.
9. Zhang, J., Zhan, N. and Dong, W. G. (2010) Altered expression of selenium-binding protein 1 in gastric carcinoma and precursor lesions. Med. Oncol. 28, 951-957.
10. Zhang, J., Dong, W. G. and Lin, J. (2011) Reduced selenium- binding protein 1 is associated with poor survival rate in gastric carcinoma. Med. Oncol. 28, 481-487.
11. Xia, Y. J., Ma, Y. Y., He, X. J., Wang, H. J., Ye, Z. Y. and Tao, H. Q. (2011) Suppression of selenium-binding protein 1 in gastric cancer is associated with poor survival. Hum. Pathol. 42, 1620-1628.
12. Silvers, A. L., Lin, L., Bass, A. J., Chen, G., Wang, Z., Thomas, D. G., Lin, J., Giordano, T. J., Orringer, M. B., Beer, D. G. and Chang, A. C. (2010) Decreased selenium- binding protein 1 in esophageal adenocarcinoma results from posttranscriptional and epigenetic regulation and affects chemosensitivity. Clin. Cancer Res. 16, 2009-2021.
13. Zhang, C., Wang, Y. E., Zhang, P., Liu, F., Sung, C. J., Steinhoff, M. M., Quddus, M. R. and Lawrence, W. D. (2010) Progressive loss of selenium-binding protein 1 expression correlates with increasing epithelial proliferation and papillary complexity in ovarian serous borderline tumor and low-grade serous carcinoma. Hum. Pathol. 41, 255-261.
14. Jeong, J. Y., Wang, Y. and Sytkowski, A. J. (2009) Human selenium binding protein-1 (hSP56) interacts with VDU1 in a selenium-dependent manner. Biochem. Biophys. Res. Commun. 379, 583-588.
15. Kaelin, W. G., Jr. and Ratcliffe, P. J. (2008) Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol. Cell 30, 393-402.
16. Ivan, M., Kondo, K., Yang, H., Kim, W., Valiando, J., Ohh, M., Salic, A., Asara, J. M., Lane, W. S. and Kaelin, W. G., Jr. (2001) HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 292, 464-468.
17. Semenza, G. L. (2003) Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3, 721-732.
18. Li, Z., Wang, D., Messing, E. M. and Wu, G. (2005) VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha. EMBO Rep. 6, 373-378.
19. Hagg, M. and Wennstrom, S. (2005) Activation of hypoxia- induced transcription in normoxia. Exp. Cell Res. 306, 180-191.
20. Jamba, L., Nehru, B., Medina, D., Bansal, M. P. and Sinha, R. (1996) Isolation and identification of selenium- labeled proteins in the mouse kidney. Anticancer Res. 16, 1651-1657.
21. Sinha, R., Bansal, M. P., Ganther, H. and Medina, D. (1993) Significance of selenium-labeled proteins for selenium's chemopreventive functions. Carcinogenesis 14, 1895-1900.
22. Flemetakis, E., Agalou, A., Kavroulakis, N., Dimou, M., Martsikovskaya, A., Slater, A., Spaink, H. P., Roussis, A. and Katinakis, P. (2002) Lotus japonicus gene Ljsbp is highly conserved among plants and animals and encodes a homologue to the mammalian selenium-binding proteins. Mol. Plant. Microbe. Interact. 15, 313-322.
23. Scortegagna, M., Martin, R. J., Kladney, R. D., Neumann, R. G. and Arbeit, J. M. (2009) Hypoxia-inducible factor- 1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition. Cancer Res. 69, 2638-2646.
24. Pass, H. I., Liu, Z., Wali, A., Bueno, R., Land, S., Lott, D., Siddiq, F., Lonardo, F., Carbone, M. and Draghici, S. (2004) Gene Expression Profiles Predict Survival and Progression of Pleural Mesothelioma. Clin. Cancer Res. 10, 849-859.
25. Pohl, N. M., Tong, C., Fang, W., Bi, X., Li, T. and Yang, W. (2009) Transcriptional regulation and biological functions of selenium-binding protein 1 in colorectal cancer in vitro and in nude mouse xenografts. PLoS One 4, e7774.
26. Glatt, S. J., Everall, I. P., Kremen, W. S., Corbeil, J., Sasik, R., Khanlou, N., Han, M., Liew, C. C. and Tsuang, M. T. (2005) Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 102, 15533-15538.
27. Kanazawa, T., Chana, G., Glatt, S. J., Mizuno, H., Masliah, E., Yoneda, H., Tsuang, M. T. and Everall, I. P. (2008) The utility of SELENBP1 gene expression as a biomarker for major psychotic disorders: replication in schizophrenia and extension to bipolar disorder with psychosis. Am J. Med. Genet. B. Neuropsychiatr. Genet. 147B, 686-689.
28. Huang, C., Ding, G., Gu, C., Zhou, J., Kuang, M., Ji, Y., He, Y., Kondo, T. and Fan, J. (2012) Decreased selenium- binding protein 1 enhances glutathione peroxidase 1 activity and downregulates HIF-1alpha to promote hepatocellular carcinoma invasiveness. Clin. Cancer Res. 18, 3042-3053.
29. Goldberg, M. A. and Schneider, T. J. (1994) Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J. Biol. Chem. 269, 4355-4359.
30. Freedman, V. H. and Shin, S. I. (1974) Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell 3, 355-359.
31. Jeong, J. Y., Feldman, L., Solar, P., Szenajch, J. and Sytkowski, A. J. (2008) Characterization of erythropoietin receptor and erythropoietin expression and function in human ovarian cancer cells. Int. J. Cancer 122, 274-280.