메뉴 건너뛰기




Volumn 32, Issue 6, 2010, Pages 599-606

Stimulation of the endosomal TLR pathway enhances autophagy-induced cell death in radiotherapy of breast cancer

Author keywords

Autophagy; Imiquimod; MCF 7; Poly(I:C); Radiotherapy; Toll like receptor (TLR)

Indexed keywords

3 METHYLADENINE; GARDIQUIMOD; IMIQUIMOD; POLYINOSINIC POLYCYTIDYLIC ACID; RAPAMYCIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

EID: 84905859552     PISSN: 19769571     EISSN: 20929293     Source Type: Journal    
DOI: 10.1007/s13258-010-0139-x     Document Type: Article
Times cited : (16)

References (37)
  • 2
    • 34548569047 scopus 로고    scopus 로고
    • Toll-like receptor ligands energize peptide vaccines through multiple paths
    • Celis E (2007) Toll-like receptor ligands energize peptide vaccines through multiple paths. Cancer Res. 67: 7945-7947.
    • (2007) Cancer Res. , vol.67 , pp. 7945-7947
    • Celis, E.1
  • 3
    • 77956117171 scopus 로고    scopus 로고
    • Newly identified CpG ODNs, M5-30 and M6-395, stimulate mouse immune cells to secrete TNF-alpha and enhance Th1-mediated immunity
    • Choi SS, Chung E and Jung YJ (2010) Newly identified CpG ODNs, M5-30 and M6-395, stimulate mouse immune cells to secrete TNF-alpha and enhance Th1-mediated immunity. J. Microbiol. 48: 512-517.
    • (2010) J. Microbiol. , vol.48 , pp. 512-517
    • Choi, S.S.1    Chung, E.2    Jung, Y.J.3
  • 4
    • 27744513830 scopus 로고    scopus 로고
    • Coexpression of CD40L and CD70 by semiallogenic tumor cells induces anti-tumor immunity
    • Cormary C, Hiver E, Mariame B, Favre G and Tilkin-Mariame AF (2005) Coexpression of CD40L and CD70 by semiallogenic tumor cells induces anti-tumor immunity. Cancer Gene Ther. 12: 963-972.
    • (2005) Cancer Gene Ther. , vol.12 , pp. 963-972
    • Cormary, C.1    Hiver, E.2    Mariame, B.3    Favre, G.4    Tilkin-Mariame, A.F.5
  • 5
    • 77950252174 scopus 로고    scopus 로고
    • Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
    • Djavaheri-Mergny M, Maiuri MC and Kroemer G (2010) Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1. Oncogene 29: 1717-1719.
    • (2010) Oncogene , vol.29 , pp. 1717-1719
    • Djavaheri-Mergny, M.1    Maiuri, M.C.2    Kroemer, G.3
  • 6
    • 70449475132 scopus 로고    scopus 로고
    • Blocking PD-1 in cancer immunotherapy
    • Dotti G (2009) Blocking PD-1 in cancer immunotherapy. Blood 114: 1457-1458.
    • (2009) Blood , vol.114 , pp. 1457-1458
    • Dotti, G.1
  • 7
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • Egen JG, Kuhns MS and Allison JP (2002) CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat. Immunol. 3: 611-618.
    • (2002) Nat. Immunol. , vol.3 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 8
    • 34249785092 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells dominate multiple immune evasion mechanisms in early but not late phases of tumor development in a B cell lymphoma model
    • Elpek KG, Lacelle C, Singh NP, Yolcu ES and Shirwan H (2007) CD4+CD25+ T regulatory cells dominate multiple immune evasion mechanisms in early but not late phases of tumor development in a B cell lymphoma model. J. Immunol. 178: 6840-6848.
    • (2007) J. Immunol. , vol.178 , pp. 6840-6848
    • Elpek, K.G.1    Lacelle, C.2    Singh, N.P.3    Yolcu, E.S.4    Shirwan, H.5
  • 10
    • 77954930632 scopus 로고    scopus 로고
    • IAPs: From caspase inhibitors to modulators of NF-kappaB, inflammation and cancer
    • Gyrd-Hansen M and Meier P (2010) IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer. Nat. Rev. Cancer 10: 561-574.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 561-574
    • Gyrd-Hansen, M.1    Meier, P.2
  • 12
    • 37849035627 scopus 로고    scopus 로고
    • TLR signaling by tumor and immune cells: A double-edged sword
    • Huang B, Zhao J, Unkeless JC, Feng ZH and Xiong H (2008) TLR signaling by tumor and immune cells: a double-edged sword. Oncogene 27: 218-224.
    • (2008) Oncogene , vol.27 , pp. 218-224
    • Huang, B.1    Zhao, J.2    Unkeless, J.C.3    Zh, F.4    Xiong, H.5
  • 14
    • 34248169629 scopus 로고    scopus 로고
    • Development of TLR9 agonists for cancer therapy
    • Krieg AM (2007) Development of TLR9 agonists for cancer therapy. J. Clin. Invest. 117: 1184-1194.
    • (2007) J. Clin. Invest. , vol.117 , pp. 1184-1194
    • Krieg, A.M.1
  • 17
    • 0033975869 scopus 로고    scopus 로고
    • Innate immune recognition: Mechanisms and pathways
    • Medzhitov R and Janeway C, Jr. (2000a) Innate immune recognition: mechanisms and pathways. Immunol. Rev. 173: 89-97.
    • (2000) Immunol. Rev. , vol.173 , pp. 89-97
    • Medzhitov, R.1    Janeway, C.2
  • 18
    • 0034307339 scopus 로고    scopus 로고
    • The Toll receptor family and microbial recognition
    • Medzhitov R and Janeway C, Jr. (2000b) The Toll receptor family and microbial recognition. Trends Microbiol. 8: 452-456.
    • (2000) Trends Microbiol. , vol.8 , pp. 452-456
    • Medzhitov, R.1    Janeway, C.2
  • 19
    • 0036812719 scopus 로고    scopus 로고
    • Effective therapeutic anticancer vaccines based on precision guiding of cytolytic T lymphocytes
    • Melief CJ, Van Der Burg SH, Toes RE, Ossendorp F and Offringa R (2002) Effective therapeutic anticancer vaccines based on precision guiding of cytolytic T lymphocytes. Immunol. Rev. 188: 177-182.
    • (2002) Immunol. Rev. , vol.188 , pp. 177-182
    • Melief, C.J.1    Van Der Burg, S.H.2    Toes, R.E.3    Ossendorp, F.4    Offringa, R.5
  • 20
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima N and Yoshimori T (2007) How to interpret LC3 immunoblotting. Autophagy 3: 542-545.
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 22
    • 33750561502 scopus 로고    scopus 로고
    • Monocyte-derived DC primed with TLR agonists secrete IL-12p70 in a CD40-dependent manner under hyperthermic conditions
    • Peng JC, Hyde C, Pai S, O'Sullivan BJ, Nielsen LK and Thomas R (2006) Monocyte-derived DC primed with TLR agonists secrete IL-12p70 in a CD40-dependent manner under hyperthermic conditions. J. Immunother. 29: 606-615.
    • (2006) J. Immunother. , vol.29 , pp. 606-615
    • Peng, J.C.1    Hyde, C.2    Pai, S.3    O'Sullivan, B.J.4    Nielsen, L.K.5    Thomas, R.6
  • 23
    • 43549112759 scopus 로고    scopus 로고
    • Bcl-2-family proteins and hematologic malignancies: History and future prospects
    • Reed JC (2008) Bcl-2-family proteins and hematologic malignancies: history and future prospects. Blood 111: 3322-3330.
    • (2008) Blood , vol.111 , pp. 3322-3330
    • Reed, J.C.1
  • 24
    • 37849008154 scopus 로고    scopus 로고
    • Radiation therapy and Toll-like receptor signaling: Implications for the treatment of cancer
    • Roses RE, Xu M, Koski GK and Czerniecki BJ (2008) Radiation therapy and Toll-like receptor signaling: implications for the treatment of cancer. Oncogene 27: 200-207.
    • (2008) Oncogene , vol.27 , pp. 200-207
    • Roses, R.E.1    Xu, M.2    Koski, G.K.3    Czerniecki, B.J.4
  • 25
    • 65049090350 scopus 로고    scopus 로고
    • Antitumor effects of an imidazoquinoline in renal cell carcinoma
    • Schwartz MJ, Liu H, Hwang DH, Kawamoto H and Scherr DS (2009) Antitumor effects of an imidazoquinoline in renal cell carcinoma. Urology 73: 1156-1162.
    • (2009) Urology , vol.73 , pp. 1156-1162
    • Schwartz, M.J.1    Liu, H.2    Hwang, D.H.3    Kawamoto, H.4    Scherr, D.S.5
  • 26
    • 50649093779 scopus 로고    scopus 로고
    • The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy
    • Smits EL, Ponsaerts P, Berneman ZN and Van Tendeloo VF (2008) The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy. Oncologist 13: 859-875.
    • (2008) Oncologist , vol.13 , pp. 859-875
    • Smits, E.L.1    Ponsaerts, P.2    Berneman, Z.N.3    Van Tendeloo, V.F.4
  • 27
    • 0036775463 scopus 로고    scopus 로고
    • IRAK-4 as the central TIR signaling mediator in innate immunity
    • Suzuki N, Suzuki S and Yeh WC (2002) IRAK-4 as the central TIR signaling mediator in innate immunity. Trends Immunol. 23: 503-506.
    • (2002) Trends Immunol. , vol.23 , pp. 503-506
    • Suzuki, N.1    Suzuki, S.2    Yeh, W.C.3
  • 28
    • 31544471136 scopus 로고    scopus 로고
    • Tumor cells transduced with the MHC class II Transactivator and CD80 activate tumor-specific CD4+ T cells whether or not they are silenced for invariant chain
    • Thompson JA, Dissanayake SK, Ksander BR, Knutson KL, Disis ML and Ostrand-Rosenberg S (2006) Tumor cells transduced with the MHC class II Transactivator and CD80 activate tumor-specific CD4+ T cells whether or not they are silenced for invariant chain. Cancer Res. 66: 1147-1154.
    • (2006) Cancer Res. , vol.66 , pp. 1147-1154
    • Thompson, J.A.1    Dissanayake, S.K.2    Ksander, B.R.3    Knutson, K.L.4    Disis, M.L.5    Ostrand-Rosenberg, S.6
  • 30
    • 35648930568 scopus 로고    scopus 로고
    • Update on toll-like receptor-directed therapies for human disease
    • Tse K and Horner AA (2007) Update on toll-like receptor-directed therapies for human disease. Ann. Rheum. Dis. 66 Suppl 3: iii77-80.
    • (2007) Ann. Rheum. Dis. , vol.66 , pp. III77-III80
    • Tse, K.1    Horner, A.A.2
  • 31
    • 4944235951 scopus 로고    scopus 로고
    • Efficacy of imiquimod for the expression of Bcl-2, Ki67, p53 and basal cell carcinoma apoptosis
    • Vidal D, Matias-Guiu X and Alomar A (2004) Efficacy of imiquimod for the expression of Bcl-2, Ki67, p53 and basal cell carcinoma apoptosis. Br. J. Dermatol. 151: 656-662.
    • (2004) Br. J. Dermatol. , vol.151 , pp. 656-662
    • Vidal, D.1    Matias-Guiu, X.2    Alomar, A.3
  • 32
    • 69049112114 scopus 로고    scopus 로고
    • Tumor-specific adenovirus-mediated PUMA gene transfer using the survivin promoter enhances radiosensitivity of breast cancer cells in vitro and in vivo
    • Wang R, Wang X, Li B, Lin F, Dong K, Gao P and Zhang HZ (2009) Tumor-specific adenovirus-mediated PUMA gene transfer using the survivin promoter enhances radiosensitivity of breast cancer cells in vitro and in vivo. Breast Cancer Res. Treat. 117: 45-54.
    • (2009) Breast Cancer Res. Treat. , vol.117 , pp. 45-54
    • Wang, R.1    Wang, X.2    Li, B.3    Lin, F.4    Dong, K.5    Gao, P.6    Zhang, H.Z.7
  • 33
    • 28644438156 scopus 로고    scopus 로고
    • The role of peroxiredoxin II in radiation-resistant MCF-7 breast cancer cells
    • Wang T, Tamae D, LeBon T, Shively JE, Yen Y and Li JJ (2005) The role of peroxiredoxin II in radiation-resistant MCF-7 breast cancer cells. Cancer Res. 65: 10338-10346.
    • (2005) Cancer Res. , vol.65 , pp. 10338-10346
    • Wang, T.1    Tamae, D.2    Lebon, T.3    Shively, J.E.4    Yen, Y.5    Li, J.J.6
  • 34
    • 77249145443 scopus 로고    scopus 로고
    • TLR signalling regulated antigen presentation in dendritic cells
    • Watts C, West MA and Zaru R (2010) TLR signalling regulated antigen presentation in dendritic cells. Curr. Opin. Immunol. 22: 124-130.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 124-130
    • Watts, C.1    West, M.A.2    Zaru, R.3
  • 35
    • 34848886914 scopus 로고    scopus 로고
    • Autophagosome formation: Core machinery and adaptations
    • Xie Z and Klionsky DJ (2007) Autophagosome formation: core machinery and adaptations. Nat. Cell Biol. 9: 1102-1109.
    • (2007) Nat. Cell Biol. , vol.9 , pp. 1102-1109
    • Xie, Z.1    Klionsky, D.J.2
  • 37
    • 66349112689 scopus 로고    scopus 로고
    • Radiation-induced autophagy in normal and cancer cells: Towards novel cytoprotection and radio- sensitization policies?
    • Zois CE and Koukourakis MI (2009) Radiation-induced autophagy in normal and cancer cells: towards novel cytoprotection and radio- sensitization policies? Autophagy 5: 442-450.
    • (2009) Autophagy , vol.5 , pp. 442-450
    • Zois, C.E.1    Koukourakis, M.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.