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Volumn 99, Issue 8, 2014, Pages

Bone mineral content in patients with congenital generalized lipodystrophy is unaffected by metreleptin replacement therapy

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTIOMETRY, PHOTON; ADOLESCENT; ADULT; BODY COMPOSITION; BONE DENSITY; BONE DEVELOPMENT; CHILD; CHILD, PRESCHOOL; FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; LEPTIN; LIPODYSTROPHY, CONGENITAL GENERALIZED; MALE; YOUNG ADULT;

EID: 84905833730     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2014-1353     Document Type: Article
Times cited : (41)

References (39)
  • 2
    • 0029073613 scopus 로고
    • Weight-reducing effects of the plasma protein encoded by the obese gene
    • Halaas JL, Gajiwala KS, Maffei M, et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science. 1995;269: 543-546.
    • (1995) Science. , vol.269 , pp. 543-546
    • Halaas, J.L.1    Gajiwala, K.S.2    Maffei, M.3
  • 3
    • 0036800760 scopus 로고    scopus 로고
    • Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
    • Farooqi IS, Matarese G, Lord GM, et al. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest. 2002;110:1093-1103.
    • (2002) J Clin Invest. , vol.110 , pp. 1093-1103
    • Farooqi, I.S.1    Matarese, G.2    Lord, G.M.3
  • 4
    • 85011486581 scopus 로고    scopus 로고
    • A leptin dose-response study in obese (ob/ob) and lean (-/-) mice
    • Harris RB, Zhou J, Redmann SM Jr, et al. A leptin dose-response study in obese (ob/ob) and lean (-/-) mice. Endocrinology. 1998; 139:8-19.
    • (1998) Endocrinology. , vol.139 , pp. 8-19
    • Harris, R.B.1    Zhou, J.2    Redmann Jr., S.M.3
  • 5
    • 0033517284 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
    • Shimomura I, Hammer RE, Ikemoto S, Brown MS, Goldstein JL. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature. 1999;401:73-76.
    • (1999) Nature. , vol.401 , pp. 73-76
    • Shimomura, I.1    Hammer, R.E.2    Ikemoto, S.3    Brown, M.S.4    Goldstein, J.L.5
  • 6
    • 0032572722 scopus 로고    scopus 로고
    • Leptin modulates the T-cell immune response and reverses starvation- induced immunosuppression
    • Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation- induced immunosuppression. Nature. 1998;394:897-901.
    • (1998) Nature. , vol.394 , pp. 897-901
    • Lord, G.M.1    Matarese, G.2    Howard, J.K.3    Baker, R.J.4    Bloom, S.R.5    Lechler, R.I.6
  • 7
    • 32544437510 scopus 로고    scopus 로고
    • Leptin replacement therapy mod ulates circulating lymphocyte subsets and cytokine responsiveness in severe lipodystrophy
    • Oral EA, Javor ED, Ding L, et al. Leptin replacement therapy mod ulates circulating lymphocyte subsets and cytokine responsiveness in severe lipodystrophy. J Clin Endocrinol Metab. 2006;91:621-628.
    • (2006) J Clin Endocrinol Metab. , vol.91 , pp. 621-628
    • Oral, E.A.1    Javor, E.D.2    Ding, L.3
  • 8
    • 0030010388 scopus 로고    scopus 로고
    • Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
    • Chehab FF, Lim ME, Lu R. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet. 1996;12:318-320.
    • (1996) Nat Genet. , vol.12 , pp. 318-320
    • Chehab, F.F.1    Lim, M.E.2    Lu, R.3
  • 9
    • 0033575993 scopus 로고    scopus 로고
    • Effects of recombinant leptin therapy in a child with congenital leptin deficiency
    • Farooqi IS, Jebb SA, LangmackG, et al. Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med. 1999;341:879-884.
    • (1999) N Engl J Med. , vol.341 , pp. 879-884
    • Farooqi, I.S.1    Jebb, S.A.2    Langmack, G.3
  • 10
    • 4344690525 scopus 로고    scopus 로고
    • Recombinant human leptin in women with hypothalamic amenorrhea
    • Welt CK, Chan JL, Bullen J, et al. Recombinant human leptin in women with hypothalamic amenorrhea. N Engl J Med. 2004;351: 987-997.
    • (2004) N Engl J Med. , vol.351 , pp. 987-997
    • Welt, C.K.1    Chan, J.L.2    Bullen, J.3
  • 11
    • 84866136855 scopus 로고    scopus 로고
    • Understanding leptin-dependent regulation of skeletal homeostasis
    • Motyl KJ, Rosen CJ. Understanding leptin-dependent regulation of skeletal homeostasis. Biochimie. 2012;94:2089-2096.
    • (2012) Biochimie. , vol.94 , pp. 2089-2096
    • Motyl, K.J.1    Rosen, C.J.2
  • 12
    • 77955766757 scopus 로고    scopus 로고
    • Leptin stimulates fibroblast growth factor 23 expression in bone and suppresses renal 1β, 25-dihydroxyvitamin D3 synthesis in leptin-deficient mice
    • Tsuji K, Maeda T, Kawane T, Matsunuma A, Horiuchi N. Leptin stimulates fibroblast growth factor 23 expression in bone and suppresses renal 1β, 25-dihydroxyvitamin D3 synthesis in leptin-deficient mice. J Bone Miner Res. 2010;25:1711-1723.
    • (2010) J Bone Miner Res. , vol.25 , pp. 1711-1723
    • Tsuji, K.1    Maeda, T.2    Kawane, T.3    Matsunuma, A.4    Horiuchi, N.5
  • 13
    • 0141737573 scopus 로고    scopus 로고
    • Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
    • Ducy P, Amling M, Takeda S, et al. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell. 2000;100:197-207.
    • (2000) Cell. , vol.100 , pp. 197-207
    • Ducy, P.1    Amling, M.2    Takeda, S.3
  • 14
    • 1542316258 scopus 로고    scopus 로고
    • Leptin deficiency produces contrasting phenotypes in bones of the limb and spine
    • Hamrick MW, Pennington C, Newton D, Xie D, Isales C. Leptin deficiency produces contrasting phenotypes in bones of the limb and spine. Bone. 2004;34:376-383.
    • (2004) Bone. , vol.34 , pp. 376-383
    • Hamrick, M.W.1    Pennington, C.2    Newton, D.3    Xie, D.4    Isales, C.5
  • 15
    • 34247546688 scopus 로고    scopus 로고
    • Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice
    • Iwaniec UT, Boghossian S, Lapke PD, Turner RT. Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice. Peptides. 2007;28:1012-1019.
    • (2007) Peptides. , vol.28 , pp. 1012-1019
    • Iwaniec, U.T.1    Boghossian, S.2    Lapke, P.D.3    Turner, R.T.4
  • 16
    • 19044381754 scopus 로고    scopus 로고
    • Leptin treatment induces loss of bone marrow adipocytes and increases bone formation in leptin-deficient ob/ob mice
    • HamrickMW, Della-FeraMA, Choi YH, Pennington C, Hartzell D, Baile CA. Leptin treatment induces loss of bone marrow adipocytes and increases bone formation in leptin-deficient ob/ob mice. J Bone Miner Res. 2005;20:994-1001.
    • (2005) J Bone Miner Res. , vol.20 , pp. 994-1001
    • Hamrick, M.W.1    Della-Fera, M.A.2    Choi, Y.H.3    Pennington, C.4    Hartzell, D.5    Baile, C.A.6
  • 17
    • 84859916102 scopus 로고    scopus 로고
    • Leptin substitution results in the induction of menstrual cycles in an adolescent with leptin deficiency and hypogonadotropic hypogonadism
    • von Schnurbein J, Moss A, Nagel SA, et al. Leptin substitution results in the induction of menstrual cycles in an adolescent with leptin deficiency and hypogonadotropic hypogonadism. Horm Res Paediatr. 2012;77:127-133.
    • (2012) Horm Res Paediatr. , vol.77 , pp. 127-133
    • Von Schnurbein, J.1    Moss, A.2    Nagel, S.A.3
  • 18
    • 0037339129 scopus 로고    scopus 로고
    • Clinical features and metabolic derangements in acquired generalized lipodystrophy: Case reports and review of the literature
    • Misra A, Garg A. Clinical features and metabolic derangements in acquired generalized lipodystrophy: case reports and review of the literature. Medicine. 2003;82:129-146.
    • (2003) Medicine. , vol.82 , pp. 129-146
    • Misra, A.1    Garg, A.2
  • 20
    • 12144288571 scopus 로고    scopus 로고
    • Changes in body composition in patients with severe lipodystrophy after leptin replacement therapy
    • Moran SA, Patten N, Young JR, et al. Changes in body composition in patients with severe lipodystrophy after leptin replacement therapy. Metabolism. 2004;53:513-519.
    • (2004) Metabolism. , vol.53 , pp. 513-519
    • Moran, S.A.1    Patten, N.2    Young, J.R.3
  • 21
    • 0036114844 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
    • Petersen KF, Oral EA, Dufour S, et al. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J Clin Invest. 2002;109:1345-1350.
    • (2002) J Clin Invest. , vol.109 , pp. 1345-1350
    • Petersen, K.F.1    Oral, E.A.2    Dufour, S.3
  • 22
    • 21344447493 scopus 로고    scopus 로고
    • Long-term efficacy of leptin replacement in patients with generalized lipodystrophy
    • Javor ED, Cochran EK, Musso C, Young JR, Depaoli AM, Gorden P. Long-term efficacy of leptin replacement in patients with generalized lipodystrophy. Diabetes. 2005;54:1994-2002.
    • (2005) Diabetes. , vol.54 , pp. 1994-2002
    • Javor, E.D.1    Cochran, E.K.2    Musso, C.3    Young, J.R.4    Depaoli, A.M.5    Gorden, P.6
  • 23
    • 33947283865 scopus 로고    scopus 로고
    • Long-term efficacy of leptin replacement in patients with Dunnigan-type familial partial lipodystrophy
    • Park JY, Javor ED, Cochran EK, DePaoli AM, Gorden P. Long-term efficacy of leptin replacement in patients with Dunnigan-type familial partial lipodystrophy. Metabolism. 2007;56:508-516.
    • (2007) Metabolism. , vol.56 , pp. 508-516
    • Park, J.Y.1    Javor, E.D.2    Cochran, E.K.3    Depaoli, A.M.4    Gorden, P.5
  • 24
    • 72449185147 scopus 로고    scopus 로고
    • Efficacy of leptin therapy in the different forms of human lipodystrophy
    • Chong AY, Lupsa BC, Cochran EK, Gorden P. Efficacy of leptin therapy in the different forms of human lipodystrophy. Diabetologia. 2010;53:27-35.
    • (2010) Diabetologia. , vol.53 , pp. 27-35
    • Chong, A.Y.1    Lupsa, B.C.2    Cochran, E.K.3    Gorden, P.4
  • 25
    • 0037148928 scopus 로고    scopus 로고
    • Leptin-replacement therapy for lipodystrophy
    • Oral EA, Simha V, Ruiz E, et al. Leptin-replacement therapy for lipodystrophy. N Engl J Med. 2002;346:570-578.
    • (2002) N Engl J Med. , vol.346 , pp. 570-578
    • Oral, E.A.1    Simha, V.2    Ruiz, E.3
  • 26
    • 16244363679 scopus 로고    scopus 로고
    • Leptin reverses nonalcoholic steatohepatitis in patients with severe lipodystrophy
    • Javor ED, Ghany MG, Cochran EK, et al. Leptin reverses nonalcoholic steatohepatitis in patients with severe lipodystrophy. Hepatology. 2005;41:753-760.
    • (2005) Hepatology. , vol.41 , pp. 753-760
    • Javor, E.D.1    Ghany, M.G.2    Cochran, E.K.3
  • 27
    • 80053482085 scopus 로고    scopus 로고
    • Revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non-black children: Results of the bone mineral density in childhood study
    • Zemel BS, Kalkwarf HJ, Gilsanz V, et al. Revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non-black children: results of the bone mineral density in childhood study. J Clin Endocrinol Metab. 2011; 96:3160-3169.
    • (2011) J Clin Endocrinol Metab. , vol.96 , pp. 3160-3169
    • Zemel, B.S.1    Kalkwarf, H.J.2    Gilsanz, V.3
  • 28
    • 70349280466 scopus 로고    scopus 로고
    • Dual energy x-ray absorptiometry body composition reference values from NHANES
    • Kelly TL, Wilson KE, Heymsfield SB. Dual energy x-ray absorptiometry body composition reference values from NHANES. PloS One. 2009;4:e7038.
    • (2009) PloS One. , vol.4
    • Kelly, T.L.1    Wilson, K.E.2    Heymsfield, S.B.3
  • 29
    • 0003556467 scopus 로고
    • Radiographic atlas of skeletal development of the hand and wrist. 2nd ed. Stanford
    • University Press;
    • Greulich WW, Pyle SI. Radiographic atlas of skeletal development of the hand and wrist. 2nd ed. Stanford, CA: Stanford University Press; 1959.
    • (1959) CA: Stanford
    • Greulich, W.W.1    Pyle, S.I.2
  • 31
    • 84875674807 scopus 로고    scopus 로고
    • Bone mineral accretion and its relationship to growth, sexual maturation and body composition during childhood and adolescence
    • Zemel B. Bone mineral accretion and its relationship to growth, sexual maturation and body composition during childhood and adolescence. World Rev Nutr Diet. 2013;106:39-45.
    • (2013) World Rev Nutr Diet. , vol.106 , pp. 39-45
    • Zemel, B.1
  • 32
    • 84879205073 scopus 로고    scopus 로고
    • Diagnostic evaluation of bone densitometric size adjustment techniques in children with and without low trauma fractures
    • Crabtree NJ, Högler W, Cooper MS, Shaw NJ. Diagnostic evaluation of bone densitometric size adjustment techniques in children with and without low trauma fractures. Osteoporos Int. 2013;24: 2015-2024.
    • (2013) Osteoporos Int. , vol.24 , pp. 2015-2024
    • Crabtree, N.J.1    Högler, W.2    Cooper, M.S.3    Shaw, N.J.4
  • 33
    • 33747735518 scopus 로고    scopus 로고
    • Elevated plasma adiponectin in humans with genetically defective insulin receptors
    • Semple RK, Soos MA, Luan J, et al. Elevated plasma adiponectin in humans with genetically defective insulin receptors. J Clin Endocrinol Metab. 2006;91:3219-3223.
    • (2006) J Clin Endocrinol Metab. , vol.91 , pp. 3219-3223
    • Semple, R.K.1    Soos, M.A.2    Luan, J.3
  • 34
    • 67651148206 scopus 로고    scopus 로고
    • In vitro and in vivo effects of adiponectin on bone
    • Williams GA, Wang Y, Callon KE, et al. In vitro and in vivo effects of adiponectin on bone. Endocrinology. 2009;150:3603-3610.
    • (2009) Endocrinology. , vol.150 , pp. 3603-3610
    • Williams, G.A.1    Wang, Y.2    Callon, K.E.3
  • 35
    • 34547123090 scopus 로고    scopus 로고
    • Jürimäe J, Jürimäe T. Plasma adiponectin concentration in healthy pre- and postmenopausal women: Relationship with body composition, bone mineral, and metabolic variables
    • Jürimäe J, Jürimäe T. Plasma adiponectin concentration in healthy pre- and postmenopausal women: relationship with body composition, bone mineral, and metabolic variables. Am J Physiol Endocrinol Metab. 2007;293:E42-E47.
    • (2007) Am J Physiol Endocrinol Metab. , vol.293
  • 36
    • 33748071110 scopus 로고    scopus 로고
    • Association between bone mass and fractures in children: A prospective cohort study
    • Clark EM, Ness AR, Bishop NJ, Tobias JH. Association between bone mass and fractures in children: a prospective cohort study. J Bone Miner Res. 2006;21:1489-1495.
    • (2006) J Bone Miner Res. , vol.21 , pp. 1489-1495
    • Clark, E.M.1    Ness, A.R.2    Bishop, N.J.3    Tobias, J.H.4
  • 37
    • 0036846461 scopus 로고    scopus 로고
    • Effect of subcutaneous leptin replacement therapy on bone metabolism in patients with generalized lipodystrophy
    • Simha V, Zerwekh JE, Sakhaee K, Garg A. Effect of subcutaneous leptin replacement therapy on bone metabolism in patients with generalized lipodystrophy. J Clin Endocrinol Metab. 2002;87: 4942-4945.
    • (2002) J Clin Endocrinol Metab. , vol.87 , pp. 4942-4945
    • Simha, V.1    Zerwekh, J.E.2    Sakhaee, K.3    Garg, A.4
  • 39
    • 84860783483 scopus 로고    scopus 로고
    • Serum leptin, parathyroid hormone, 1, 25-dihydroxyvitamin D, fibroblast growth factor 23, bone alkaline phosphatase, and sclerostin relationships in obesity
    • Grethen E, Hill KM, Jones R, et al. Serum leptin, parathyroid hormone, 1, 25-dihydroxyvitamin D, fibroblast growth factor 23, bone alkaline phosphatase, and sclerostin relationships in obesity. J Clin Endocrinol Metab. 2012;97:1655-1662. Diseases
    • (2012) J Clin Endocrinol Metab. , vol.97 , pp. 1655-1662
    • Grethen, E.1    Hill, K.M.2    Jones, R.3


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