Grizzly bears exhibit augmented insulin sensitivity while obese prior to a reversible insulin resistance during hibernation

Cell Metabolism

Volumn 20, Issue 2, 2014, Pages 376-382

  Nelson, O Lynne ^a   Jansen, Heiko T ^a   Galbreath, Elizabeth ^b   Morgenstern, Kurt ^b   Gehring, Jamie Lauren ^a   Rigano, Kimberly Scott ^a   Lee, Jae ^b   Gong, Jianhua ^b   Shaywitz, Adam J ^b,d   Vella, Chantal A ^c   Robbins, Charles T ^a   Corbit, Kevin C ^b  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b AMGEN INC   (United States)

^c UNIVERSITY OF IDAHO   (United States)

^d BIOMARIN PHARMACEUTICAL INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE BLOOD LEVEL; INSULIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ADIPOSE TISSUE; ANALYSIS; ANIMAL; BEAR; BLOOD; BODY WEIGHT; FEMALE; GLUCOSE BLOOD LEVEL; HAPLOINSUFFICIENCY; HIBERNATION; INSULIN RESISTANCE; MALE; METABOLISM; OBESITY; PATHOLOGY; PHOSPHORYLATION; SEASON; SIGNAL TRANSDUCTION;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; FEMALE; HAPLOINSUFFICIENCY; HIBERNATION; INSULIN; INSULIN RESISTANCE; MALE; OBESITY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SEASONS; SIGNAL TRANSDUCTION; URSIDAE;

EID: 84905732123     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.07.008     Document Type: Article

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