Characterization of the lipid binding properties of otoferlin reveals specific interactions between PI(4,5)P2 and the C2C and C2F Domains

Biochemistry

Volumn 53, Issue 30, 2014, Pages 5023-5033

  Padmanarayana, Murugesh ^a   Hams, Nicole ^a   Speight, Lee C ^b   Petersson, E James ^b   Mehl, Ryan A ^a   Johnson, Colin P ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; EMISSION SPECTROSCOPY; ENZYME ACTIVITY; FLUORESCENCE SPECTROSCOPY; LIPID BILAYERS; LIPOSOMES;

CALCIUM CONCENTRATION; CALCIUM-BINDING DOMAIN; ENVIRONMENTALLY SENSITIVE; ISOTHERMAL TITRATION CALORIMETRY; PHOSPHATIDYLINOSITOL 4 ,5-BISPHOSPHATE; SPECIFIC INTERACTION; TRANS-MEMBRANE PROTEINS; UNNATURAL AMINO ACIDS;

CALCIUM;

CARBON; HUMANS; LIPID BILAYERS; MEMBRANE PROTEINS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84905695329     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi5004469     Document Type: Article

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