-
1
-
-
84860663487
-
The descriptive epidemiology of female breast cancer: an international comparison of screening, incidence, survival and mortality
-
Youlden,D.R. et al. (2012) The descriptive epidemiology of female breast cancer: an international comparison of screening, incidence, survival and mortality. Cancer Epidemiol., 36, 237-248.
-
(2012)
Cancer Epidemiol
, vol.36
, pp. 237-248
-
-
Youlden, D.R.1
-
2
-
-
77950963920
-
U.S. Department of Health and Human Services: The NCI Strategic Plan for Leading the Nation to Eliminate the Suffering and Death Due to Cancer
-
National Cancer Institute (NCI), Bethesda, MD: NCI
-
National Cancer Institute (NCI), U.S. Department of Health and Human Services: The NCI Strategic Plan for Leading the Nation to Eliminate the Suffering and Death Due to Cancer. Bethesda, MD: NCI; 2006.
-
(2006)
-
-
-
3
-
-
84880859236
-
Vitronectin-αvβ3 integrin engagement directs hypoxia-resistant mTOR activity and sustained protein synthesis linked to invasion by breast cancer cells
-
Pola,C. et al. (2013) Vitronectin-αvβ3 integrin engagement directs hypoxia-resistant mTOR activity and sustained protein synthesis linked to invasion by breast cancer cells. Cancer Res., 73, 4571-4578.
-
(2013)
Cancer Res
, vol.73
, pp. 4571-4578
-
-
Pola, C.1
-
4
-
-
84857128956
-
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis
-
Nagalingam,A. et al.(2012) Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis. Breast Cancer Res., 14, R35.
-
(2012)
Breast Cancer Res
, vol.14
-
-
Nagalingam, A.1
-
5
-
-
84882597506
-
Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells
-
Martinelli,E. et al.(2013) Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells. Int J Cancer., 133, 2089-2101.
-
(2013)
Int J Cancer
, vol.133
, pp. 2089-2101
-
-
Martinelli, E.1
-
6
-
-
84877063389
-
The Importance of the PI3K/AKT/MTOR pathway in the progression of ovarian cancer
-
Dobbin,Z.C. et al.(2013) The Importance of the PI3K/AKT/MTOR pathway in the progression of ovarian cancer. Int J Mol Sci., 14, 8213-8227.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 8213-8227
-
-
Dobbin, Z.C.1
-
7
-
-
84878977228
-
Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway
-
Zhang,D.M. et al.(2013) Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway. Carcinogenesis., 34, 1331-1342.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1331-1342
-
-
Zhang, D.M.1
-
8
-
-
84875013867
-
Fibroblast growth factor 2 induces E-cadherin down-regulation via PI3K/Akt/mTOR and MAPK/ERK signaling in ovarian cancer cells
-
Lau,M.T. et al.(2013) Fibroblast growth factor 2 induces E-cadherin down-regulation via PI3K/Akt/mTOR and MAPK/ERK signaling in ovarian cancer cells. PLoS One., 8, e59083.
-
(2013)
PLoS One
, vol.8
-
-
Lau, M.T.1
-
9
-
-
40349106029
-
The potential role of mTOR inhibitors in non-small cell lung cancer
-
Gridelli,C. et al.(2008) The potential role of mTOR inhibitors in non-small cell lung cancer. Oncologist., 13, 139-147.
-
(2008)
Oncologist
, vol.13
, pp. 139-147
-
-
Gridelli, C.1
-
10
-
-
84876536055
-
Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse
-
Manne,N.D. et al.(2013) Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse. Int J Oncol., 42, 2134-2140.
-
(2013)
Int J Oncol
, vol.42
, pp. 2134-2140
-
-
Manne, N.D.1
-
11
-
-
84862979856
-
Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model
-
Perez,J. et al. (2012) Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model. PLoS One., 7, e32458.
-
(2012)
PLoS One
, vol.7
-
-
Perez, J.1
-
12
-
-
84878986499
-
Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis
-
Wang,X. et al.(2013) Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis. Carcinogenesis., 34, 1323-1330.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1323-1330
-
-
Wang, X.1
-
13
-
-
84863317475
-
Genetic variants in the PI3K/PTEN/AKT/mTOR pathway predict head and neck cancer patient second primary tumor/recurrence risk and response to retinoid chemoprevention
-
Hildebrandt,M.A. et al.(2012) Genetic variants in the PI3K/PTEN/AKT/mTOR pathway predict head and neck cancer patient second primary tumor/recurrence risk and response to retinoid chemoprevention. Clin Cancer Res., 18, 3705-3713.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3705-3713
-
-
Hildebrandt, M.A.1
-
14
-
-
84862912936
-
Current development of the second generation of mTOR inhibitors as anticancer agents
-
Zhou,H.Y. et al.(2012) Current development of the second generation of mTOR inhibitors as anticancer agents. Chin J Cancer., 31, 8-18.
-
(2012)
Chin J Cancer
, vol.31
, pp. 8-18
-
-
Zhou, H.Y.1
-
15
-
-
84856438701
-
High mTOR expression is associated with a worse oncological outcome in laryngeal carcinoma treated with postoperative radiotherapy: a pilot study
-
Lionello,M. et al.(2012) High mTOR expression is associated with a worse oncological outcome in laryngeal carcinoma treated with postoperative radiotherapy: a pilot study. J Oral Pathol Med., 41, 136-140.
-
(2012)
J Oral Pathol Med
, vol.41
, pp. 136-140
-
-
Lionello, M.1
-
16
-
-
84870908872
-
Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells
-
Zou,Z. et al.(2012) Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells. Autophagy., 8, 1798-1810.
-
(2012)
Autophagy
, vol.8
, pp. 1798-1810
-
-
Zou, Z.1
-
17
-
-
84876989771
-
Promise of rapalogues versus mTOR kinase inhibitors in subset specific breast cancer: old targets new hope
-
De,P. et al.(2013) Promise of rapalogues versus mTOR kinase inhibitors in subset specific breast cancer: old targets new hope. Cancer Treat Rev., 39, 403-412.
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 403-412
-
-
De, P.1
-
18
-
-
84876863294
-
Current status and future perspectives of PI3K and mTOR inhibitor as anticancer drugs in breast cancer
-
Zhang,X. et al.(2013) Current status and future perspectives of PI3K and mTOR inhibitor as anticancer drugs in breast cancer. Curr Cancer Drug Targets., 13, 175-187.
-
(2013)
Curr Cancer Drug Targets
, vol.13
, pp. 175-187
-
-
Zhang, X.1
-
19
-
-
84872540201
-
Flavonoids, flavonoid subclasses and breast cancer risk: a meta-analysis of epidemiologic studies
-
Hui,C. et al.(2013) Flavonoids, flavonoid subclasses and breast cancer risk: a meta-analysis of epidemiologic studies. PLoS One., 8, e54318.
-
(2013)
PLoS One
, vol.8
-
-
Hui, C.1
-
20
-
-
84876081750
-
Citrus fruit intake and breast cancer risk: a quantitative systematic review
-
Song,J.K. et al.(2013) Citrus fruit intake and breast cancer risk: a quantitative systematic review. J Breast Cancer., 16, 72-76.
-
(2013)
J Breast Cancer
, vol.16
, pp. 72-76
-
-
Song, J.K.1
-
21
-
-
84869748019
-
Profiling flavonoid cytotoxicity in human breast cancer cell lines: determination of structure-function relationships
-
Yadegarynia,S. et al.(2012) Profiling flavonoid cytotoxicity in human breast cancer cell lines: determination of structure-function relationships. Nat Prod Commun., 7, 1295-1304.
-
(2012)
Nat Prod Commun
, vol.7
, pp. 1295-1304
-
-
Yadegarynia, S.1
-
22
-
-
78249284364
-
Anticancer activities of an anthocyanin-rich extract from black rice against breast cancer cells in vitro and in vivo
-
Hui,C. et al.(2010) Anticancer activities of an anthocyanin-rich extract from black rice against breast cancer cells in vitro and in vivo. Nutr Cancer., 62, 1128-1136.
-
(2010)
Nutr Cancer
, vol.62
, pp. 1128-1136
-
-
Hui, C.1
-
23
-
-
84862796733
-
Ampelopsin sodium exhibits antitumor effects against bladder carcinoma in orthotopic xenograft models
-
Zhang,B. et al.(2012) Ampelopsin sodium exhibits antitumor effects against bladder carcinoma in orthotopic xenograft models. Anticancer Drugs., 23, 590-596.
-
(2012)
Anticancer Drugs
, vol.23
, pp. 590-596
-
-
Zhang, B.1
-
24
-
-
84856091690
-
Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-κB signaling pathways
-
Qi,S. et al.(2012) Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-κB signaling pathways. Int Immunopharmacol., 12, 278-287.
-
(2012)
Int Immunopharmacol
, vol.12
, pp. 278-287
-
-
Qi, S.1
-
25
-
-
84861897760
-
Flavonoid ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice
-
Ni,F. et al.(2012) Flavonoid ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice. PLoS One., 7, e38802.
-
(2012)
PLoS One
, vol.7
-
-
Ni, F.1
-
26
-
-
84861447253
-
Diallyl trisulfide as an inhibitor of benzo(a)pyrene-induced precancerous carcinogenesis in MCF-10A cells
-
Nkrumah-Elie,Y.M. et al.(2012) Diallyl trisulfide as an inhibitor of benzo(a)pyrene-induced precancerous carcinogenesis in MCF-10A cells. Food Chem Toxicol., 50, 2524-2530.
-
(2012)
Food Chem Toxicol
, vol.50
, pp. 2524-2530
-
-
Nkrumah-Elie, Y.M.1
-
27
-
-
84880300172
-
Cancer chemoprevention: a rapidly evolving field
-
Steward,W.P. et al.(2013) Cancer chemoprevention: a rapidly evolving field. Br J Cancer., 109, 1-7.
-
(2013)
Br J Cancer
, vol.109
, pp. 1-7
-
-
Steward, W.P.1
-
28
-
-
84864941592
-
Breast cancer chemoprevention: old and new approaches
-
Cazzaniga,M. et al.(2012) Breast cancer chemoprevention: old and new approaches. J Biomed Biotechnol., 985620.
-
(2012)
J Biomed Biotechnol
, pp. 985620
-
-
Cazzaniga, M.1
-
29
-
-
84896815337
-
mTOR inhibitors: changing landscape of endocrine-resistant breast cancer
-
Chumsri,S. et al.(2014) mTOR inhibitors: changing landscape of endocrine-resistant breast cancer. Future Oncol., 10, 443-456.
-
(2014)
Future Oncol
, vol.10
, pp. 443-456
-
-
Chumsri, S.1
-
30
-
-
84901465453
-
Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition
-
Zhang,H. et al.(2014) Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition. Breast Cancer Res., 16, R36.
-
(2014)
Breast Cancer Res
, vol.16
-
-
Zhang, H.1
-
31
-
-
84896867375
-
Biomarker changes associated with the development of resistance to aromatase inhibitors (AIs) in estrogen receptor-positive breast cancer
-
Arnedos,M. et al.(2014) Biomarker changes associated with the development of resistance to aromatase inhibitors (AIs) in estrogen receptor-positive breast cancer. Ann Oncol., 25, 605-610.
-
(2014)
Ann Oncol
, vol.25
, pp. 605-610
-
-
Arnedos, M.1
-
32
-
-
84899096068
-
Epigenetic Reprogramming of HOXC10 in Endocrine-Resistant Breast Cancer
-
Pathiraja,T.N. et al.(2014) Epigenetic Reprogramming of HOXC10 in Endocrine-Resistant Breast Cancer. Sci Transl Med., 6, 229ra41.
-
(2014)
Sci Transl Med
, vol.6
-
-
Pathiraja, T.N.1
-
33
-
-
84880015651
-
Autocrine IGF-I/insulin receptor axis compensates for inhibition of AKT in ER-positive breast cancer cells with resistance to estrogen deprivation
-
Fox,E.M. et al.(2013) Autocrine IGF-I/insulin receptor axis compensates for inhibition of AKT in ER-positive breast cancer cells with resistance to estrogen deprivation. Breast Cancer Res., 15, R55.
-
(2013)
Breast Cancer Res
, vol.15
-
-
Fox, E.M.1
-
34
-
-
77954974573
-
Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer
-
Miller,T.W. et al.(2010) Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer. J Clin Invest., 120, 2406-2413.
-
(2010)
J Clin Invest
, vol.120
, pp. 2406-2413
-
-
Miller, T.W.1
-
35
-
-
84893646332
-
A phase II study of combined fulvestrant and everolimus in patients with metastatic estrogen receptor (ER)-positive breast cancer after aromatase inhibitor (AI) failure
-
Massarweh,S. et al.(2014) A phase II study of combined fulvestrant and everolimus in patients with metastatic estrogen receptor (ER)-positive breast cancer after aromatase inhibitor (AI) failure. Breast Cancer Res Treat., 143, 325-332.
-
(2014)
Breast Cancer Res Treat
, vol.143
, pp. 325-332
-
-
Massarweh, S.1
-
36
-
-
84868237217
-
Mammalian target of rapamycin as a rational therapeutic target for breast cancer treatment
-
LoRusso,P.M. (2013) Mammalian target of rapamycin as a rational therapeutic target for breast cancer treatment. Oncology., 84, 43-56.
-
(2013)
Oncology
, vol.84
, pp. 43-56
-
-
LoRusso, P.M.1
-
37
-
-
84873432372
-
Inhibition of rapamycin-induced AKT activation elicits differential antitumor response in head and neck cancers
-
Radhakrishnan,P. et al.(2013) Inhibition of rapamycin-induced AKT activation elicits differential antitumor response in head and neck cancers. Cancer Res., 73, 1118-1127.
-
(2013)
Cancer Res
, vol.73
, pp. 1118-1127
-
-
Radhakrishnan, P.1
-
38
-
-
84867459604
-
Dual Inhibition of PI3K/Akt/mTOR pathway and role of autophagy in non-small cell lung cancer cells
-
Jeong,E.H. et al.(2012) Dual Inhibition of PI3K/Akt/mTOR pathway and role of autophagy in non-small cell lung cancer cells. Tuberc Respir Dis (Seoul)., 72, 343-351.
-
(2012)
Tuberc Respir Dis (Seoul).
, vol.72
, pp. 343-351
-
-
Jeong, E.H.1
|