Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: A novel apoptosis-independent autophagic signaling pathway

Phytotherapy Research

Volumn 28, Issue 8, 2014, Pages 1153-1162

  Ghosh, Samrat ^a   Bishayee, Kausik ^a   Khuda Bukhsh, Anisur Rahman ^a  

^a UNIVERSITY OF KALYANI   (India)

Author keywords

apoptosis; autophagy; Beclin 1; programmed cell death; reactive oxygen species

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 METHYLADENINE; ALCOHOL; BECLIN 1; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; GRAVEOLINE; PLANT MEDICINAL PRODUCT; REACTIVE OXYGEN METABOLITE; RUTA GRAVEOLENS EXTRACT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; IMMUNOBLOTTING; INTRACELLULAR SIGNALING; MELANOMA CELL; MELANOMA SKIN CANCER; PROTEIN EXPRESSION;

RUTA GRAVEOLENS;

APOPTOSIS; AUTOPHAGY; BECLIN-1; PROGRAMMED CELL DEATH; REACTIVE OXYGEN SPECIES;

ADENINE; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE, TUMOR; HUMANS; MELANOMA; MEMBRANE PROTEINS; METHOXSALEN; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; RUTA; SIGNAL TRANSDUCTION;

EID: 84905663924     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5107     Document Type: Article

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