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Volumn 11, Issue 10, 2011, Pages 929-939

Protein targets for anticancer gold compounds: Mechanistic inferences

Author keywords

Cancer; Gold compounds; Metal protein adducts; Proteins

Indexed keywords

ALLOCRYSIN; ANTINEOPLASTIC AGENT; AUOXO1; AUOXO2; AUOXO3; AUOXO4; AUOXO5; AUOXO6; AURANOFIN; AURO BIS(THIOSULFATE); AUROTHIOGLUCOSE; AUROTHIOMALATE; CISPLATIN; GOLD DERIVATIVE; PROTEASOME; PROTEIN KINASE C IOTA; SODIUM AUROTHIOSULFATE; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 80055108291     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/187152011797927607     Document Type: Article
Times cited : (33)

References (46)
  • 1
    • 27844432489 scopus 로고    scopus 로고
    • Gold-based therapeutic agents
    • Shaw, CF III. Gold-based therapeutic agents. Chem. Rev., 1999, 99, 2589-2600.
    • (1999) Chem. Rev. , vol.99 , pp. 2589-2600
    • Shaw III, C.F.1
  • 2
    • 77951999997 scopus 로고    scopus 로고
    • Gold compounds as anticancer agents: Chemistry, cellular pharmacology, and preclinical studies
    • Nobili, S.; Mini, E.; Landini, I.; Gabbiani, C.; Casini, A.; Messori, L. Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies. Med. Res. Rev., 2010, 30, 550-580.
    • (2010) Med. Res. Rev. , vol.30 , pp. 550-580
    • Nobili, S.1    Mini, E.2    Landini, I.3    Gabbiani, C.4    Casini, A.5    Messori, L.6
  • 7
    • 62449242847 scopus 로고    scopus 로고
    • Gold(III) porphyrin complex is more potent than cisplatin in inhibiting growth of nasopharyngeal carcinoma in vitro and in vivo
    • To, YF; Sun, RW; Chen, Y; Chan, VS; Yu, WY; Tam, PK; Che, CM; Lin, CL. Gold(III) porphyrin complex is more potent than cisplatin in inhibiting growth of nasopharyngeal carcinoma in vitro and in vivo. Int. J. Cancer, 2009, 124, 1971-1979.
    • (2009) Int. J. Cancer. , vol.124 , pp. 1971-1979
    • To, Y.F.1    Sun, R.W.2    Chen, Y.3    Chan, V.S.4    Yu, W.Y.5    Tam, P.K.6    Che, C.M.7    Lin, C.L.8
  • 8
    • 33644532836 scopus 로고    scopus 로고
    • Gold(III) compound is a novel chemocytotoxic agent for hepatocellular carcinoma
    • Lum, CT; Yang, ZF; Li, HY; Wai-Yin Sun, R;Fan, ST; Poon, RT;Lin, MC; Che, CM; Kung, HF. Gold(III) compound is a novel chemocytotoxic agent for hepatocellular carcinoma. Int. J. Cancer, 2006, 118, 1527-1538.
    • (2006) Int. J. Cancer. , vol.118 , pp. 1527-1538
    • Lum, C.T.1    Yang, Z.F.2    Li, H.Y.3    Wai-Yin, S.4
  • 11
    • 70349561362 scopus 로고    scopus 로고
    • Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: A systematic study
    • Casini, A; Kelter, G; Gabbiani, C; Cinellu, MA; Minghetti, G; Fregona, D; Fiebig, HH; Messori, L. Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study. J Biol. Inorg. Chem., 2009, 14, 1139-1149.
    • (2009) J Biol. Inorg. Chem. , vol.14 , pp. 1139-1149
    • Casini, A.1    Kelter, G.2    Gabbiani, C.3    Cinellu, M.A.4    Minghetti, G.5    Fregona, D.6    Fiebig, H.H.7    Messori, L.8
  • 12
    • 34250652117 scopus 로고    scopus 로고
    • 'Targeting the mitochondrial cell death pathway with gold compounds
    • Barnard, P.J.; Berners-Price, S.J. 'Targeting the mitochondrial cell death pathway with gold compounds', Coord. Chem.y Rev., 2007, 251, 1889-1902.
    • (2007) Coord. Chem.y Rev. , vol.251 , pp. 1889-1902
    • Barnard, P.J.1    Berners-Price, S.J.2
  • 13
    • 0001100775 scopus 로고    scopus 로고
    • Kinetics and Mechanism of the Reaction between Serum Albumin and Auranofin
    • Xiao, J; Schliesman, B; Parsons, DJ; Shaw, CF 3rd. Kinetics and Mechanism of the Reaction between Serum Albumin and Auranofin (and Its Isopropyl Analogue) in vitro. Inorg. Chem. 1996, 35, 424-433.
    • (1996) Inorg. Chem. , vol.35 , pp. 424-433
    • Xiao, J.1    Schliesman, B.2    Parsons, D.J.3    Shaw, C.F.4
  • 14
    • 0025171528 scopus 로고
    • Evidence for a glutathionegold-albumin metabolite
    • Shaw, CF 3rd; Isab, AA; Coffer MT, Mirabelli CK.Gold(I) efflux from auranofin-treated red blood cells. Evidence for a glutathionegold-albumin metabolite. Biochem. Pharmacol., 1990, 40, 1227-1234.
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 1227-1234
    • Shaw 3rd, C.F.1    Isab, A.A.2    Coffer, M.T.3
  • 15
    • 44349154204 scopus 로고    scopus 로고
    • Spectroscopic evidence for the formation of goldfingers
    • Franzman, MA; Barrios, AM. Spectroscopic evidence for the formation of goldfingers. Inorg. Chem., 2008, 47, 3928-3930.
    • (2008) Inorg. Chem. , vol.47 , pp. 3928-3930
    • Franzman, M.A.1    Barrios, A.M.2
  • 16
    • 52449114832 scopus 로고    scopus 로고
    • Mitochondria-targeted chemotherapeutics: The rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols
    • Hickey, JL; Ruhayel, RA; Barnard, PJ; Baker, MV; Berners-Price, SJ; Filipovska, A. Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols. J. Am. Chem. Soc., 2008, 130, 12570-12571.
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 12570-12571
    • Hickey, J.L.1    Ruhayel, R.A.2    Barnard, P.J.3    Baker, M.V.4    Berners-Price, S.J.5    Filipovska, A.6
  • 19
    • 79951861884 scopus 로고    scopus 로고
    • Bioinorganic and medicinal chemistry: Aspects of gold(I)-protein complexes
    • Krishna, P.; Bhabak, Bhaskar J. Bhuyan and Govindasamy Mugesh, Bioinorganic and medicinal chemistry: aspects of gold(I)- protein complexes Dalton Trans., 2011, 40, 2099-2111.
    • (2011) Dalton Trans , vol.40 , pp. 2099-2111
    • Krishna, P.1    Bhabak2    Mugesh, G.3
  • 21
    • 39249084976 scopus 로고    scopus 로고
    • Gold(III) compounds as anticancer agents: Relevance of gold-protein interactions for their mechanism of action
    • Casini, A; Hartinger, C; Gabbiani, C; Mini, E; Dyson, PJ; Keppler, BK; Messori, L. Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action. J. Inorg. Biochem., 2008, 102, 564-575.
    • (2008) J. Inorg. Biochem. , vol.102 , pp. 564-575
    • Casini, A.1    Hartinger, C.2    Gabbiani, C.3    Mini, E.4    Dyson, P.J.5    Keppler, B.K.6    Messori, L.7
  • 23
    • 33748531865 scopus 로고    scopus 로고
    • Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands
    • Casini, A; Cinellu, MA; Minghetti, G; Gabbiani, C; Coronnello, M; Mini, E; Messori L. Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands. J. Med. Chem., 2006, 49, 5524-5531.
    • (2006) J. Med. Chem. , vol.49 , pp. 5524-5531
    • Casini, A.1    Cinellu, M.A.2    Minghetti, G.3    Gabbiani, C.4    Coronnello, M.5    Mini, E.6    Messori, L.7
  • 24
    • 64049113556 scopus 로고    scopus 로고
    • The anti-cancer properties of gold(III) compounds with dianionic porphyrin and tetradentate ligands
    • Wai-Yin Sun R., Che C.-M. The anti-cancer properties of gold(III) compounds with dianionic porphyrin and tetradentate ligands Coord. Chem. Rev., 2009, 253, 1682-1691.
    • (2009) Coord. Chem. Rev. , vol.253 , pp. 1682-1691
    • Wai-Yin, S.R.1    Che, C.-M.2
  • 25
    • 77649206626 scopus 로고    scopus 로고
    • Che, CM Stable anticancer gold(III)-porphyrin complexes: Effects of porphyrin structure
    • Sun, RW; Li, CK; Ma, DL; Yan, JJ; Lok, CN; Leung, CH; Zhu, N; Che, CM Stable anticancer gold(III)-porphyrin complexes: effects of porphyrin structure. Chemistry. 2010, 16, 3097-3113.
    • (2010) Chemistry , vol.16 , pp. 3097-3113
    • Sun, R.W.1    Li, C.K.2    Ma, D.L.3    Yan, J.J.4    Lok, C.N.5    Leung, C.H.6    Zhu, N.7
  • 26
    • 0242277285 scopus 로고    scopus 로고
    • The thioredoxin system-from science to clinic
    • Gromer, S; Urig, S; Becker, K. The thioredoxin system-from science to clinic. Med Res Rev. 2004, 24, 40-89.
    • (2004) Med Res Rev , vol.24 , pp. 40-89
    • Gromer, S.1    Urig, S.2    Becker, K.3
  • 27
    • 67349120863 scopus 로고    scopus 로고
    • Focus on mammalian thioredoxin reductases-important selenoproteins with versatile functions
    • Arnér, ES. Focus on mammalian thioredoxin reductases-important selenoproteins with versatile functions. Biochim. Biophys. ACTA. 2009, 1790, 495-526.
    • (2009) Biochim. Biophys. ACTA. , vol.1790 , pp. 495-526
    • Arnér, E.S.1
  • 28
  • 29
    • 77956481191 scopus 로고    scopus 로고
    • Reactions of medicinally relevant gold compounds with the C-terminal motif of thioredoxin reductase elucidated by MS analysis
    • Pratesi, A; Gabbiani, C; Ginanneschi, M; Messori, L. Reactions of medicinally relevant gold compounds with the C-terminal motif of thioredoxin reductase elucidated by MS analysis. Chem. Commun. (Camb). 2010, 46, 7001-7003.
    • (2010) Chem. Commun. , vol.46 , pp. 7001-7003
    • Pratesi, A.1    Gabbiani, C.2    Ginanneschi, M.3    Messori, L.4
  • 31
    • 78049264771 scopus 로고    scopus 로고
    • The 26S proteasome: Assembly and function of a destructive machine
    • [Gallastegui, N; Groll, M. The 26S proteasome: assembly and function of a destructive machine. Trends Biochem. Sci. 2010, 35, 634-642.
    • (2010) Trends Biochem , vol.35 , pp. 634-642
    • Gallastegui, N.1    Groll, M.2
  • 32
    • 78651321769 scopus 로고    scopus 로고
    • The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention
    • Chen, D; Dou, QP. The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention. Curr. Protein Pept. Sci., 2010, 11, 459-470.
    • (2010) Curr. Protein Pept. Sci. , vol.11 , pp. 459-470
    • Chen, D.1    Dou, Q.P.2
  • 33
    • 77951660776 scopus 로고    scopus 로고
    • Latest insights into the anticancer activity of gold(III)-dithiocarbamato complexes
    • Ronconi, L; Aldinucci, D; Dou, QP; Fregona, D. Latest insights into the anticancer activity of gold(III)-dithiocarbamato complexes. Anticancer Agents Med Chem., 2010, 10, 283-292.
    • (2010) Anticancer Agents Med Chem , vol.10 , pp. 283-292
    • Ronconi, L.1    Aldinucci, D.2    Dou, Q.P.3    Fregona, D.4
  • 34
    • 64449085700 scopus 로고    scopus 로고
    • The tumor proteasome as a novel target for gold(III) complexes: Implications for breast cancer therapy
    • Milacic, V; Dou, QP. The tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapy. Coord Chem Rev. 2009, 253, 1649-1660.
    • (2009) Coord Chem Rev , vol.253 , pp. 1649-1660
    • Milacic, V.1    Dou, Q.P.2
  • 35
    • 0032104245 scopus 로고    scopus 로고
    • The extended protein kinase C superfamily
    • Mellor, H; Parker, PJ The extended protein kinase C superfamily. Biochem. J., 1998, 332, 281-292.
    • (1998) Biochem. J. , vol.332 , pp. 281-292
    • Mellor, H.1    Parker, P.J.2
  • 36
    • 79251508328 scopus 로고    scopus 로고
    • Protein kinase C expression and oncogenic signaling mechanisms in cancer
    • Murray, NR; Kalari, KR; Fields, AP. Protein kinase C expression and oncogenic signaling mechanisms in cancer. J. Cell Physiol., 2011, 226, 879-887.
    • (2011) J. Cell Physiol. , vol.226 , pp. 879-887
    • Murray, N.R.1    Kalari, K.R.2    Fields, A.P.3
  • 37
    • 36749037936 scopus 로고    scopus 로고
    • Targeting the oncogenic protein kinase Ciota signalling pathway for the treatment of cancer
    • Fields, AP; Frederick, LA; Regala, RP. Targeting the oncogenic protein kinase Ciota signalling pathway for the treatment of cancer. Biochem Soc Trans., 2007, 35, 996-1000.
    • (2007) Biochem Soc Trans , vol.35 , pp. 996-1000
    • Fields, A.P.1    Frederick, L.A.2    Regala, R.P.3
  • 38
    • 32944470373 scopus 로고    scopus 로고
    • A novel small-molecule inhibitor of protein kinase Ciota blocks transformed growth of non-small-cell lung cancer cells
    • Stallings-Mann, M; Jamieson, L; Regala, RP; Weems, C; Murray, NR; Fields, AP. A novel small-molecule inhibitor of protein kinase Ciota blocks transformed growth of non-small-cell lung cancer cells. Cancer Res., 2006, 66, 1767-1774.
    • (2006) Cancer Res , vol.66 , pp. 1767-1774
    • Stallings-Mann, M.1    Jamieson, L.2    Regala, R.P.3    Weems, C.4    Murray, N.R.5    Fields, A.P.6
  • 39
    • 48649092328 scopus 로고    scopus 로고
    • Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells
    • Regala, RP; Thompson, EA; Fields, AP. Atypical protein kinase C iota expression and aurothiomalate sensitivity in human lung cancer cells. Cancer Res., 2008, 68, 5888-5895.
    • (2008) Cancer Res , vol.68 , pp. 5888-5895
    • Regala, R.P.1    Thompson, E.A.2    Fields, A.P.3
  • 40
    • 29744448918 scopus 로고    scopus 로고
    • Mechanisms of aurothiomalate-Cys2His2 zinc finger interactions
    • Larabee JL, Hocker JR, Hanas JS. Mechanisms of aurothiomalate-Cys2His2 zinc finger interactions Chem. Res. Toxicol., 2005 18,1943-154
    • (2005) Chem. Res. Toxicol. , vol.18 , pp. 1943-1954
    • Larabee, J.L.1    Hocker, J.R.2    Hanas, J.S.3
  • 41
    • 44349154204 scopus 로고    scopus 로고
    • Spectroscopic evidence for the formation of goldfingers
    • [Franzman MA, Barrios AM Spectroscopic evidence for the formation of goldfingers. Inorg. Chem., 2008, 473928-473930.
    • (2008) Inorg. Chem. , pp. 473928-473930
    • Franzman, M.A.1    Barrios, A.M.2
  • 42
    • 70349425673 scopus 로고    scopus 로고
    • Zinc finger proteins as templates for metal ion exchange: Substitution effects on the Cfinger of HIV nucleocapsid NCp7 using
    • de Paula QA, Mangrum JB, Farrell NP Zinc finger proteins as templates for metal ion exchange: Substitution effects on the Cfinger of HIV nucleocapsid NCp7 using M(chelate) species (M=Pt, Pd, Au). J. Inorg. Biochem., 2009,103, 1347-1354.
    • (2009) J. Inorg. Biochem. , vol.103 , pp. 1347-1354
    • de Paula, Q.A.1    Mangrum, J.B.2    Farrell, N.P.3
  • 44
    • 77951657455 scopus 로고    scopus 로고
    • Proteomic and metallomic strategies for understanding the mode of action of anticancer metallodrugs
    • Gabbiani, C; Magherini, F; Modesti, A; Messori, L. Proteomic and metallomic strategies for understanding the mode of action of anticancer metallodrugs. Anticancer Agents Med. Chem., 2010, 10, 324-337.
    • (2010) Anticancer Agents Med. Chem. , vol.10 , pp. 324-337
    • Gabbiani, C.1    Magherini, F.2    Modesti, A.3    Messori, L.4
  • 45
    • 31344472931 scopus 로고    scopus 로고
    • Proteomic characterization of the cytotoxic mechanism of gold (III) porphyrin 1a, a potential anticancer drug
    • Wang, Y; He, QY; Che CM, Chiu JF. Proteomic characterization of the cytotoxic mechanism of gold (III) porphyrin 1a, a potential anticancer drug. Proteomics, 2006, 6, 131-142.
    • (2006) Proteomics , vol.6 , pp. 131-142
    • Wang, Y.1    He, Q.Y.2    Che, C.M.3    Chiu, J.F.4


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