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Volumn 111, Issue 2, 2004, Pages 184-191

Immunodetection and quantification of vascular endothelial growth factor receptor-3 in human malignant tumor tissues

Author keywords

Growth factors; Lymphangiogenesis; Sandwich ELISA; VEGFR 3

Indexed keywords

GROWTH FACTOR; LIGAND; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; VASCULOTROPIN RECEPTOR 3;

EID: 3142677896     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20211     Document Type: Article
Times cited : (43)

References (48)
  • 1
    • 0033047875 scopus 로고    scopus 로고
    • VEGFs, receptors and angiogenesis
    • Veikkola T, Alitalo K. VEGFs, receptors and angiogenesis. Semin Cancer Biol 1999;9:211-20.
    • (1999) Semin Cancer Biol , vol.9 , pp. 211-220
    • Veikkola, T.1    Alitalo, K.2
  • 2
    • 0029021904 scopus 로고
    • Endothelial receptor tyrosine kinases involved in angiogenesis
    • Mustonen T, Alitalo K. Endothelial receptor tyrosine kinases involved in angiogenesis. J Cell Biol 1995;29:895-98.
    • (1995) J Cell Biol , vol.29 , pp. 895-898
    • Mustonen, T.1    Alitalo, K.2
  • 3
    • 0028940091 scopus 로고
    • Biochemical characterization of two isoforms of FLT4, a VEGF receptor-related tyrosine kinase
    • Borg JP, deLapeyriere O, Noguchi T, Rottapel R, Dubreuil P, Birnbaum D. Biochemical characterization of two isoforms of FLT4, a VEGF receptor-related tyrosine kinase. Oncogene 1995;10:973-84.
    • (1995) Oncogene , vol.10 , pp. 973-984
    • Borg, J.P.1    DeLapeyriere, O.2    Noguchi, T.3    Rottapel, R.4    Dubreuil, P.5    Birnbaum, D.6
  • 5
    • 0030635889 scopus 로고    scopus 로고
    • Lymphangiogenesis: Mechanisms, significance and clinical implications
    • Witte MH, Way DL, Witte CL, Bernas M. Lymphangiogenesis: mechanisms, significance and clinical implications. Exs 1997;79:65-112.
    • (1997) Exs , vol.79 , pp. 65-112
    • Witte, M.H.1    Way, D.L.2    Witte, C.L.3    Bernas, M.4
  • 8
    • 0032053767 scopus 로고    scopus 로고
    • Signaling in angiogenesis and lymphangiogenesis
    • Korpelainen EI, Alitalo K. Signaling in angiogenesis and lymphangiogenesis. Curr Opin Cell Biol 1998;10:159-64.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 159-164
    • Korpelainen, E.I.1    Alitalo, K.2
  • 10
    • 0031213636 scopus 로고    scopus 로고
    • VEGF and VEGF-C specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane
    • Oh SJ, Jeltsch MM, Birkenhaeger R, McCarthy JE, Weich HA, Christ B, Alitalo K, Wilting J. VEGF and VEGF-C specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. Dev Biol 1997;188:96-09.
    • (1997) Dev Biol , vol.188 , pp. 96-09
    • Oh, S.J.1    Jeltsch, M.M.2    Birkenhaeger, R.3    McCarthy, J.E.4    Weich, H.A.5    Christ, B.6    Alitalo, K.7    Wilting, J.8
  • 12
    • 0033862310 scopus 로고    scopus 로고
    • Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase
    • Irrthum A, Karkkainen MJ, Devriendt K, Alitalo K, Vikkula M. Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase. Am J Hum Genet 2000;67:295-301.
    • (2000) Am J Hum Genet , vol.67 , pp. 295-301
    • Irrthum, A.1    Karkkainen, M.J.2    Devriendt, K.3    Alitalo, K.4    Vikkula, M.5
  • 14
    • 1242306185 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C is secreted from cells in cultrue and detectable in tumour tissue lysates-a new assay for quantification by ELISA
    • Weich HA, Bando H, Brokelmann M, Baumann P, Toi M, Barleon B, Alitalo K, Sipos B, Sleeman J. (2004) Vascular endothelial growth factor-C is secreted from cells in cultrue and detectable in tumour tissue lysates-a new assay for quantification by ELISA. J. Immun. Methods Vol. 285, 145-155.
    • (2004) J. Immun. Methods , vol.285 , pp. 145-155
    • Weich, H.A.1    Bando, H.2    Brokelmann, M.3    Baumann, P.4    Toi, M.5    Barleon, B.6    Alitalo, K.7    Sipos, B.8    Sleeman, J.9
  • 17
    • 0030026897 scopus 로고    scopus 로고
    • A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt-4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
    • Joukov V, Pajusola K, Kaipainen A, Chilov D, Lahtinen I, Kukk E, Saksela O, Kalkkinen N, Alitalo K. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt-4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J 1996;15:290-98.
    • (1996) EMBO J , vol.15 , pp. 290-298
    • Joukov, V.1    Pajusola, K.2    Kaipainen, A.3    Chilov, D.4    Lahtinen, I.5    Kukk, E.6    Saksela, O.7    Kalkkinen, N.8    Alitalo, K.9
  • 19
    • 0031867648 scopus 로고    scopus 로고
    • Differential binding characteristics and cellular inhibition by soluble forms of KDR and FLT-1
    • Röckl W, Hecht D, Sztajer H, Waltenberger J, Yayon A, Weich HA. Differential binding characteristics and cellular inhibition by soluble forms of KDR and FLT-1. J Exp Cell Res 1998;241:161-7.
    • (1998) J Exp Cell Res , vol.241 , pp. 161-167
    • Röckl, W.1    Hecht, D.2    Sztajer, H.3    Waltenberger, J.4    Yayon, A.5    Weich, H.A.6
  • 21
  • 22
    • 0032795396 scopus 로고    scopus 로고
    • Detection and quantification of complexed and free soluble human vascular endothelial growth factor receptor-1 (sVEGFR-1) by ELISA
    • Hornig C, Behn T, Bartsch W, Yayon A, Weich HA. Detection and quantification of complexed and free soluble human vascular endothelial growth factor receptor-1 (sVEGFR-1) by ELISA. J Immunol Methods 1999;226:169-77.
    • (1999) J Immunol Methods , vol.226 , pp. 169-177
    • Hornig, C.1    Behn, T.2    Bartsch, W.3    Yayon, A.4    Weich, H.A.5
  • 23
    • 0036497957 scopus 로고    scopus 로고
    • Significance of vascular endothelial growth factor (VEGF)/soluble VEGF receptor-1 relationship in breat cancer
    • Toi M, Bando H, Ogawa T, Muta M, Hornig C, Weich HA. Significance of vascular endothelial growth factor (VEGF)/soluble VEGF receptor-1 relationship in breat cancer. Int J Cancer 2002;98:14-8.
    • (2002) Int J Cancer , vol.98 , pp. 14-18
    • Toi, M.1    Bando, H.2    Ogawa, T.3    Muta, M.4    Hornig, C.5    Weich, H.A.6
  • 24
    • 0028939826 scopus 로고
    • Clinical importance of the determination of tumor angiogenesis in breast carcinoma: Much more than a new prognostic tool
    • Gasparini G, Harris AL. Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool. J Clin Oncol 1995;13:765-83.
    • (1995) J Clin Oncol , vol.13 , pp. 765-783
    • Gasparini, G.1    Harris, A.L.2
  • 25
    • 0019452902 scopus 로고
    • Indirect enzyme linked immunosorbent assay (ELISA): Practical aspects of standardization and quality control
    • McLaren ML, Lillywhite JE, Au AC. Indirect enzyme linked immunosorbent assay (ELISA): practical aspects of standardization and quality control. Med Lab Sci 1981;38:245-51.
    • (1981) Med Lab Sci , vol.38 , pp. 245-251
    • McLaren, M.L.1    Lillywhite, J.E.2    Au, A.C.3
  • 27
    • 0242330142 scopus 로고    scopus 로고
    • Lymphatic endothelium: Morphological, molecular and functional properties
    • Pepper M, Skobe M. Lymphatic endothelium: morphological, molecular and functional properties. J Cell Biol. 2003;163:209-13.
    • (2003) J Cell Biol , vol.163 , pp. 209-213
    • Pepper, M.1    Skobe, M.2
  • 28
    • 0028091775 scopus 로고
    • Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors
    • Pajusola K, Aprelikova O, Pelicci G, Weich H, Claesson-Welsh L, Alitalo K. Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors. Oncogene 1994;9:3545-55.
    • (1994) Oncogene , vol.9 , pp. 3545-3555
    • Pajusola, K.1    Aprelikova, O.2    Pelicci, G.3    Weich, H.4    Claesson-Welsh, L.5    Alitalo, K.6
  • 29
    • 0030453355 scopus 로고    scopus 로고
    • VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
    • Kukk E, Lymboussaki A, Taira S, Kaipainen A, Jeltsch M, Joukov V, Alitalo K. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development 1996;122:3829-37.
    • (1996) Development , vol.122 , pp. 3829-3837
    • Kukk, E.1    Lymboussaki, A.2    Taira, S.3    Kaipainen, A.4    Jeltsch, M.5    Joukov, V.6    Alitalo, K.7
  • 31
    • 0036289044 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endothelia
    • Witmer AN, Dai J, Weich HA, Vrensen GF, Schlingemann RO. Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endothelia. J Histochem Cytochem 2002;50:767-77.
    • (2002) J Histochem Cytochem , vol.50 , pp. 767-777
    • Witmer, A.N.1    Dai, J.2    Weich, H.A.3    Vrensen, G.F.4    Schlingemann, R.O.5
  • 33
    • 0035886701 scopus 로고    scopus 로고
    • Markers for the lymphatic endothelium: In search of the holy grail?
    • Sleeman JP, Krishnan J, Kirkin V, Baumann P. Markers for the lymphatic endothelium: in search of the holy grail? Microsc Res Tech 2001;55:61-9.
    • (2001) Microsc Res Tech , vol.55 , pp. 61-69
    • Sleeman, J.P.1    Krishnan, J.2    Kirkin, V.3    Baumann, P.4
  • 34
    • 0029079943 scopus 로고
    • Mutation at tyrosine residue 1337 abrogates ligand-dependent transforming capacity of the FLT4 receptor
    • Fournier E, Dubreuil P, Birnbaum D, Borg JP. Mutation at tyrosine residue 1337 abrogates ligand-dependent transforming capacity of the FLT4 receptor. Oncogene 1995;11:921-31.
    • (1995) Oncogene , vol.11 , pp. 921-931
    • Fournier, E.1    Dubreuil, P.2    Birnbaum, D.3    Borg, J.P.4
  • 35
    • 0033814892 scopus 로고    scopus 로고
    • VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
    • Partanen TA, Arola J, Saaristo A, Jussila L, Ora A, Miettinen M, Stacker SA, Achen MG, Alitalo K. VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J 2000;14:2087-96.
    • (2000) FASEB J , vol.14 , pp. 2087-2096
    • Partanen, T.A.1    Arola, J.2    Saaristo, A.3    Jussila, L.4    Ora, A.5    Miettinen, M.6    Stacker, S.A.7    Achen, M.G.8    Alitalo, K.9
  • 37
    • 0033846016 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing
    • Paavonen K, Puolakkainen P, Jussila L, Jahkola T, Alitalo K. Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing. Am J Pathol 2000;156:1499-504.
    • (2000) Am J Pathol , vol.156 , pp. 1499-1504
    • Paavonen, K.1    Puolakkainen, P.2    Jussila, L.3    Jahkola, T.4    Alitalo, K.5
  • 38
    • 0037024472 scopus 로고    scopus 로고
    • Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
    • He Y, Kozaki K, Karpanen T, Koshikawa K, Yla-Herttuala S, Takahashi T, Alitalo K. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling. J Natl Cancer Inst 2002;94:819-25.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 819-825
    • He, Y.1    Kozaki, K.2    Karpanen, T.3    Koshikawa, K.4    Yla-Herttuala, S.5    Takahashi, T.6    Alitalo, K.7
  • 39
    • 0037310399 scopus 로고    scopus 로고
    • Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats
    • Krishnan J, Kirkin V, Steffen A, Hegen M, Weih D, Tomarev S, Wilting J, and Sleeman J P. Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats. Cancer Res 2003;63:713-22.
    • (2003) Cancer Res , vol.63 , pp. 713-722
    • Krishnan, J.1    Kirkin, V.2    Steffen, A.3    Hegen, M.4    Weih, D.5    Tomarev, S.6    Wilting, J.7    Sleeman, J.P.8
  • 40
    • 0034899437 scopus 로고    scopus 로고
    • Lymphangiogenesis and tumor metastasis: Myth or reality
    • Pepper MS. Lymphangiogenesis and tumor metastasis: myth or reality. Clin Cancer Res 2001;7:462-8.
    • (2001) Clin Cancer Res , vol.7 , pp. 462-468
    • Pepper, M.S.1
  • 43
    • 1142270447 scopus 로고    scopus 로고
    • Quantitative analysis of lymphangiogenic markers in human colorectal cancer
    • Parr C, Jiang WG. Quantitative analysis of lymphangiogenic markers in human colorectal cancer. Int J Oncol 2003;23:533-9.
    • (2003) Int J Oncol , vol.23 , pp. 533-539
    • Parr, C.1    Jiang, W.G.2
  • 44
    • 0037439321 scopus 로고    scopus 로고
    • Clinical significance of vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 in patients with nonsmall cell lung carcinoma
    • Arinaga M, Noguchi T, Takeno S, Chujo M, Miura T, Uchida Y. Clinical significance of vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 in patients with nonsmall cell lung carcinoma. Cancer 2003;97:457-64.
    • (2003) Cancer , vol.97 , pp. 457-464
    • Arinaga, M.1    Noguchi, T.2    Takeno, S.3    Chujo, M.4    Miura, T.5    Uchida, Y.6
  • 45
    • 0037139527 scopus 로고    scopus 로고
    • Intratumoral lymphatic vessels: A case of mistaken identity or malfunction?
    • Jain RK, Fenton BT. Intratumoral lymphatic vessels: a case of mistaken identity or malfunction? J Natl Cancer Inst 2002;94:417-21.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 417-421
    • Jain, R.K.1    Fenton, B.T.2
  • 46
    • 0037085765 scopus 로고    scopus 로고
    • Vasdcular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy
    • Dias S, Choy M, Alitalo K. Vasdcular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood 2002;99:2179-84.
    • (2002) Blood , vol.99 , pp. 2179-2184
    • Dias, S.1    Choy, M.2    Alitalo, K.3
  • 47
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo
    • Plate KH, Breier G, Weich HA, Risau W. Vascular endothelial growth factor is a potential tumor angiogenesis factor in human gliomas in vivo. Nature 1992;359:845-7.
    • (1992) Nature , vol.359 , pp. 845-847
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 48
    • 0031030706 scopus 로고    scopus 로고
    • Induction of VEGF and VEGF receptors gene expression by hypoxia: Divergent regulation in vivo and in vitro
    • Sandner P, Wolf K, Bergmaier U, Gess B, Kutz A. Induction of VEGF and VEGF receptors gene expression by hypoxia: divergent regulation in vivo and in vitro. Kidney Int 1997;51:448-53.
    • (1997) Kidney Int , vol.51 , pp. 448-453
    • Sandner, P.1    Wolf, K.2    Bergmaier, U.3    Gess, B.4    Kutz, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.