메뉴 건너뛰기




Volumn 5, Issue MAY, 2014, Pages

The natural history of transfer RNA and its interactions with the ribosome

Author keywords

Non coding RNA; Origin of life; Phylogenetic analysis; Ribosome; Sequence; Structure; Translation

Indexed keywords


EID: 84905641536     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2014.00127     Document Type: Article
Times cited : (31)

References (44)
  • 1
    • 77449133028 scopus 로고    scopus 로고
    • Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu
    • doi: 10.1017/S0033583509990060
    • Agirrezabala, X., and Frank, J. (2009). Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu. Q. Rev. Biophys. 42, 159-200. doi: 10.1017/S0033583509990060
    • (2009) Q. Rev. Biophys. , vol.42 , pp. 159-200
    • Agirrezabala, X.1    Frank, J.2
  • 2
    • 0031930042 scopus 로고    scopus 로고
    • Origin of the metazoan phyla: molecular clocks confirm paleontological studies
    • doi: 10.1073/pnas.95.2.606
    • Ayala, F. J., Rzhetsky, A., and Ayala, F. J. (1998). Origin of the metazoan phyla: molecular clocks confirm paleontological studies. Proc. Natl. Acad. Sci. U.S.A. 95, 606-611. doi: 10.1073/pnas.95.2.606
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 606-611
    • Ayala, F.J.1    Rzhetsky, A.2    Ayala, F.J.3
  • 3
    • 74249115345 scopus 로고    scopus 로고
    • Topology links RNA secondary structure with global conformation, dynamics, and adaptation
    • doi: 10.1126/science.1181085
    • Bailor, M. H., Sun, X., and Al-Hashimi, H. M. (2010). Topology links RNA secondary structure with global conformation, dynamics, and adaptation. Science 327, 202-206. doi: 10.1126/science.1181085
    • (2010) Science , vol.327 , pp. 202-206
    • Bailor, M.H.1    Sun, X.2    Al-Hashimi, H.M.3
  • 4
    • 0036606550 scopus 로고    scopus 로고
    • Tracing the evolution of RNA structure in ribosomes
    • doi: 10.1093/nar/30.11.2575
    • Caetano-Anollés, G. (2002a). Tracing the evolution of RNA structure in ribosomes. Nucleic Acids Res. 30, 2575-2587. doi: 10.1093/nar/30.11.2575
    • (2002) Nucleic Acids Res. , vol.30 , pp. 2575-2587
    • Caetano-Anollés, G.1
  • 5
    • 0036182064 scopus 로고    scopus 로고
    • Evolved RNA secondary structure and the rooting of the universal tree of life
    • doi: 10.1007/s00239-001-0048-3
    • Caetano-Anollés, G. (2002b). Evolved RNA secondary structure and the rooting of the universal tree of life. J. Mol. Evol. 54, 333-345. doi: 10.1007/s00239-001-0048-3
    • (2002) J. Mol. Evol. , vol.54 , pp. 333-345
    • Caetano-Anollés, G.1
  • 6
    • 0038486929 scopus 로고    scopus 로고
    • An evolutionarily structured universe of protein architecture
    • doi: 10.1101/gr.1161903
    • Caetano-Anollés, G., and Caetano-Anollés, D. (2003). An evolutionarily structured universe of protein architecture. Genome Res. 13, 1563-1571. doi: 10.1101/gr.1161903
    • (2003) Genome Res. , vol.13 , pp. 1563-1571
    • Caetano-Anollés, G.1    Caetano-Anollés, D.2
  • 7
    • 84876783818 scopus 로고    scopus 로고
    • The coevolutionary roots of biochemistry and cellular organization challenge the RNA world paradigm
    • doi: 10.1159/000346551
    • Caetano-Anollés, G., and Seufferheld, M. (2013). The coevolutionary roots of biochemistry and cellular organization challenge the RNA world paradigm. J. Mol. Microbiol. Biotechnol. 23, 152-177. doi: 10.1159/000346551
    • (2013) J. Mol. Microbiol. Biotechnol. , vol.23 , pp. 152-177
    • Caetano-Anollés, G.1    Seufferheld, M.2
  • 8
    • 84882621993 scopus 로고    scopus 로고
    • Structural phylogenomics retrodicts the origin of the genetic code and uncovers the evolutionary impact of protein flexibility
    • doi: 10.1371/journal.pone.0072225
    • Caetano-Anollés, G., Wang, M., and Caetano-Anollés, D. (2013). Structural phylogenomics retrodicts the origin of the genetic code and uncovers the evolutionary impact of protein flexibility. PLoS ONE 8:e72225. doi: 10.1371/journal.pone.0072225
    • (2013) PLoS ONE , vol.8
    • Caetano-Anollés, G.1    Wang, M.2    Caetano-Anollés, D.3
  • 9
    • 59849127275 scopus 로고    scopus 로고
    • The origin, evolution and structure of the protein world
    • doi: 10.1042/BJ20082063
    • Caetano-Anollés, G., Wang, M., Caetano-Anolles, D., and Mittenthal, J. E. (2009). The origin, evolution and structure of the protein world. Biochem. J. 417, 621-637. doi: 10.1042/BJ20082063
    • (2009) Biochem. J. , vol.417 , pp. 621-637
    • Caetano-Anollés, G.1    Wang, M.2    Caetano-Anolles, D.3    Mittenthal, J.E.4
  • 10
    • 84874833757 scopus 로고    scopus 로고
    • Structural phylogenomics reveals gradual evolutionary replacement of abiotic chemistries by protein enzymes in purine metabolism
    • doi: 10.1371/journal.pone.0059300
    • Caetano-Anollés, K., and Caetano-Anollés, G. (2013). Structural phylogenomics reveals gradual evolutionary replacement of abiotic chemistries by protein enzymes in purine metabolism. PLoS ONE 8:e59300. doi: 10.1371/journal.pone.0059300
    • (2013) PLoS ONE , vol.8
    • Caetano-Anollés, K.1    Caetano-Anollés, G.2
  • 11
    • 84873496121 scopus 로고    scopus 로고
    • Evolutionary optimization of protein folding
    • doi: 10.1371/journal.pcbi.1002861
    • Debes, C., Wang, M., Caetano-Anollees, G., and Gräter, F. (2013). Evolutionary optimization of protein folding. PLoS Comput. Biol. 9:e1002861. doi: 10.1371/journal.pcbi.1002861
    • (2013) PLoS Comput. Biol. , vol.9
    • Debes, C.1    Wang, M.2    Caetano-Anollees, G.3    Gräter, F.4
  • 12
    • 0028500173 scopus 로고
    • The phylogeny of tRNA molecules and the origin of the genetic code
    • doi: 10.1007/BF01582018
    • Di Giulio, M. (1994). The phylogeny of tRNA molecules and the origin of the genetic code. Orig. Life Evol. Biosph. 24, 425-434. doi: 10.1007/BF01582018
    • (1994) Orig. Life Evol. Biosph. , vol.24 , pp. 425-434
    • Di Giulio, M.1
  • 13
    • 84861648979 scopus 로고    scopus 로고
    • The origin of the tRNA molecule: independent data favor a specific model of its evolution
    • doi: 10.1016/j.biochi.2012.01.014
    • Di Giulio, M. (2012). The origin of the tRNA molecule: independent data favor a specific model of its evolution. Biochimie 94, 1464-1466. doi: 10.1016/j.biochi.2012.01.014
    • (2012) Biochimie , vol.94 , pp. 1464-1466
    • Di Giulio, M.1
  • 15
    • 84881262125 scopus 로고    scopus 로고
    • Suggested phylogeny of tRNAs based on the construction of ancestral sequences
    • doi: 10.1016/j.jtbi.2013.06.033
    • Farias, S. T. (2013). Suggested phylogeny of tRNAs based on the construction of ancestral sequences. J. Theor. Biol. 335, 245-248. doi: 10.1016/j.jtbi.2013.06.033
    • (2013) J. Theor. Biol. , vol.335 , pp. 245-248
    • Farias, S.T.1
  • 16
    • 0023471213 scopus 로고
    • The phylogeny of tRNA sequences provides evidence for ambiguity reduction in the origin of the genetic code
    • doi: 10.1101/SQB.1987.052.01.085
    • Fitch, W. M., and Upper, K. (1987). The phylogeny of tRNA sequences provides evidence for ambiguity reduction in the origin of the genetic code. Cold Spring Harb. Symp. Quant. Biol. 52, 759-767. doi: 10.1101/SQB.1987.052.01.085
    • (1987) Cold Spring Harb. Symp. Quant. Biol. , vol.52 , pp. 759-767
    • Fitch, W.M.1    Upper, K.2
  • 17
    • 71549148346 scopus 로고    scopus 로고
    • tRNA as active chemical scaffold for diverse chemical transformations
    • doi: 10.1016/j.febslet.2009.11.045
    • Francklyn, C. S., and Minajigi, A. (2010). tRNA as active chemical scaffold for diverse chemical transformations. FEBS Lett. 584, 366-375. doi: 10.1016/j.febslet.2009.11.045
    • (2010) FEBS Lett. , vol.584 , pp. 366-375
    • Francklyn, C.S.1    Minajigi, A.2
  • 18
    • 84861141850 scopus 로고    scopus 로고
    • PRORP proteins support RNase P activity in both organelles and the nucleus in arabidopsis
    • doi: 10.1101/gad.189514.112
    • Gutmann, B., Gobert, A., and Giegé, P. (2012). PRORP proteins support RNase P activity in both organelles and the nucleus in arabidopsis. Genes Dev. 26, 1022-1027. doi: 10.1101/gad.189514.112
    • (2012) Genes Dev. , vol.26 , pp. 1022-1027
    • Gutmann, B.1    Gobert, A.2    Giegé, P.3
  • 19
    • 0031000512 scopus 로고    scopus 로고
    • Discrete determinants in transfer RNA for editing and aminoacylation
    • doi: 10.1126/science.276.5316.1250
    • Hale, S. P., Auld, D. S., Schmidt, E., and Schimmel, P. (1997). Discrete determinants in transfer RNA for editing and aminoacylation. Science 276, 1250-1252. doi: 10.1126/science.276.5316.1250
    • (1997) Science , vol.276 , pp. 1250-1252
    • Hale, S.P.1    Auld, D.S.2    Schmidt, E.3    Schimmel, P.4
  • 20
    • 84858040413 scopus 로고    scopus 로고
    • Ribosomal history reveals origins of modern protein synthesis
    • doi: 10.1371/journal.pone.0032776
    • Harish, A., and Caetano-Anollés, G. (2012). Ribosomal history reveals origins of modern protein synthesis. PLoS ONE 7:e32776. doi: 10.1371/journal.pone.0032776
    • (2012) PLoS ONE , vol.7
    • Harish, A.1    Caetano-Anollés, G.2
  • 21
    • 0030484686 scopus 로고    scopus 로고
    • Patterns of phylogenetic tree balance with variable or evolving speciation rates
    • doi: 10.2307/2410685
    • Heard, S. B. (1996). Patterns of phylogenetic tree balance with variable or evolving speciation rates. Evolution 50, 2141-2148. doi: 10.2307/2410685
    • (1996) Evolution , vol.50 , pp. 2141-2148
    • Heard, S.B.1
  • 22
    • 84870448969 scopus 로고    scopus 로고
    • Comparative analysis of RNA families reveals distinct repertoires for each domain of life
    • doi: 10.1371/journal.pcbi.1002752
    • Hoeppner, M. P., Gardner P. P., and Poole, A. M. (2012). Comparative analysis of RNA families reveals distinct repertoires for each domain of life. PLoS Comput. Biol. 8:e1002752. doi: 10.1371/journal.pcbi.1002752
    • (2012) PLoS Comput. Biol. , vol.8
    • Hoeppner, M.P.1    Gardner, P.P.2    Poole, A.M.3
  • 23
    • 84884839966 scopus 로고    scopus 로고
    • What can information-asymmetric games tell us about the context of Crick's 'frozen accident'?
    • doi: 10.1098/rsif.2013.0614
    • Jee, J., Sundstrom, A., Massey, S. E., and Mishra, B. (2013). What can information-asymmetric games tell us about the context of Crick's 'frozen accident'? J. R. Soc. Interface 10:20130614. doi: 10.1098/rsif.2013.0614
    • (2013) J. R. Soc. Interface , vol.10 , pp. 20130614
    • Jee, J.1    Sundstrom, A.2    Massey, S.E.3    Mishra, B.4
  • 24
    • 84862908451 scopus 로고    scopus 로고
    • Protein domain structure uncovers the origin of aerobic metabolism and the rise of planetary oxygen
    • doi: 10.1016/j.str.2011.11.003
    • Kim, K. M., Qin, T., Jiang, Y.-Y., Xiong, M., Caetano-Anollés, D., Zhang, H.-Y., et al. (2012). Protein domain structure uncovers the origin of aerobic metabolism and the rise of planetary oxygen. Structure 20, 67-76. doi: 10.1016/j.str.2011.11.003
    • (2012) Structure , vol.20 , pp. 67-76
    • Kim, K.M.1    Qin, T.2    Jiang, Y.-Y.3    Xiong, M.4    Caetano-Anollés, D.5    Zhang, H.-Y.6
  • 25
    • 58049198302 scopus 로고    scopus 로고
    • Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM
    • doi: 10.1038/emboj.2008.243
    • Li, W., Agirrezabala, X., Lei, J., Bouakaz, L., Brunelle, J. L., Ortiz-Meoz, R. F., et al. (2008). Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM. EMBO J. 27, 3322-3331. doi: 10.1038/emboj.2008.243
    • (2008) EMBO J. , vol.27 , pp. 3322-3331
    • Li, W.1    Agirrezabala, X.2    Lei, J.3    Bouakaz, L.4    Brunelle, J.L.5    Ortiz-Meoz, R.F.6
  • 26
    • 0028961335 scopus 로고
    • SCOP: a structural classification of proteins database for the investigation of sequences and structures
    • doi: 10.1016/S0022-2836(05)80134-2
    • Murzin, A. G., Brenner, S. E., Hubbard, T., and Chothia, C. (1995). SCOP: a structural classification of proteins database for the investigation of sequences and structures. J. Mol. Biol. 247, 536-540. doi: 10.1016/S0022-2836(05)80134-2
    • (1995) J. Mol. Biol. , vol.247 , pp. 536-540
    • Murzin, A.G.1    Brenner, S.E.2    Hubbard, T.3    Chothia, C.4
  • 27
    • 18844413446 scopus 로고    scopus 로고
    • Structural insights into translational fidelity
    • doi: 10.1146/annurev.biochem.74.061903.155440
    • Ogle, J. M., and Ramakrishnan, V. (2005). Structural insights into translational fidelity. Annu. Rev. Biochem. 74, 129-177. doi: 10.1146/annurev.biochem.74.061903.155440
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 129-177
    • Ogle, J.M.1    Ramakrishnan, V.2
  • 28
    • 0030777303 scopus 로고    scopus 로고
    • CATH-a hierarchic classification of protein domain structures
    • doi: 10.1016/S0969-2126(97)00260-8
    • Orengo, C. A., Michie, A., Jones, S., Jones, D. T., Swindells, M., and Thornton, J. M. (1997). CATH-a hierarchic classification of protein domain structures. Structure 5, 1093-1109. doi: 10.1016/S0969-2126(97)00260-8
    • (1997) Structure , vol.5 , pp. 1093-1109
    • Orengo, C.A.1    Michie, A.2    Jones, S.3    Jones, D.T.4    Swindells, M.5    Thornton, J.M.6
  • 29
    • 43049088477 scopus 로고    scopus 로고
    • Life without RNase P
    • doi: 10.1038/nature06833
    • Randau, L., Schröder, I., and Söll, D. (2008). Life without RNase P. Nature 453, 120-123. doi: 10.1038/nature06833
    • (2008) Nature , vol.453 , pp. 120-123
    • Randau, L.1    Schröder, I.2    Söll, D.3
  • 30
    • 78449288755 scopus 로고    scopus 로고
    • Cellular mechanisms that control mistranslation
    • doi: 10.1038/nrmicro2472
    • Reynolds, N. M., Lazazzera, B. A., and Ibba, M. (2010). Cellular mechanisms that control mistranslation. Nat. Rev. Microbiol. 8, 849-856. doi: 10.1038/nrmicro2472
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 849-856
    • Reynolds, N.M.1    Lazazzera, B.A.2    Ibba, M.3
  • 31
    • 38649093627 scopus 로고    scopus 로고
    • The origin and evolution of tRNA inferred from phylogenetic analysis of structure
    • doi: 10.1007/s00239-007-9050-8
    • Sun, F.-J., and Caetano-Anollés, G. (2008a). The origin and evolution of tRNA inferred from phylogenetic analysis of structure. J. Mol. Evol. 66, 21-35. doi: 10.1007/s00239-007-9050-8
    • (2008) J. Mol. Evol. , vol.66 , pp. 21-35
    • Sun, F.-J.1    Caetano-Anollés, G.2
  • 32
    • 53949094757 scopus 로고    scopus 로고
    • Transfer RNA and the origin of diversified life
    • doi: 10.3184/003685008X360650
    • Sun, F.-J., and Caetano-Anollés, G. (2008b). Transfer RNA and the origin of diversified life. Sci. Prog. 91, 265-284. doi: 10.3184/003685008X360650
    • (2008) Sci. Prog. , vol.91 , pp. 265-284
    • Sun, F.-J.1    Caetano-Anollés, G.2
  • 33
    • 50949084622 scopus 로고    scopus 로고
    • Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code
    • doi: 10.1371/journal.pone.0002799
    • Sun, F.-J., and Caetano-Anollés, G. (2008c). Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code. PLoS ONE 3:e2799. doi: 10.1371/journal.pone.0002799
    • (2008) PLoS ONE , vol.3
    • Sun, F.-J.1    Caetano-Anollés, G.2
  • 34
    • 72449132771 scopus 로고    scopus 로고
    • The evolutionary history of the structure of 5S ribosomal RNA
    • doi: 10.1007/s00239-009-9264-z
    • Sun, F.-J., and Caetano-Anollés, G. (2009). The evolutionary history of the structure of 5S ribosomal RNA. J. Mol. Evol. 69, 430-443. doi: 10.1007/s00239-009-9264-z
    • (2009) J. Mol. Evol. , vol.69 , pp. 430-443
    • Sun, F.-J.1    Caetano-Anollés, G.2
  • 35
    • 77952276437 scopus 로고    scopus 로고
    • The ancient history of the structure of ribonuclease P and the early origins of archaea
    • doi: 10.1186/1471-2105-11-153
    • Sun, F. J., and Caetano-Anollés, G. (2010). The ancient history of the structure of ribonuclease P and the early origins of archaea. BMC Bioinformatics 11:153. doi: 10.1186/1471-2105-11-153
    • (2010) BMC Bioinformatics , vol.11 , pp. 153
    • Sun, F.J.1    Caetano-Anollés, G.2
  • 37
    • 84885535303 scopus 로고    scopus 로고
    • Phylogenetic utility of RNA structure: evolution's arrow and emergence of modern biochemistry and diversified life
    • ed G. Caetano-Anollés (Hoboken, NJ: Wiley-Blackwell)
    • Sun, F.-J., Harish, A., and Caetano-Anolles, G. (2010) "Phylogenetic utility of RNA structure: evolution's arrow and emergence of modern biochemistry and diversified life," in Evolutionary Bioinformatics and Systems Biology, ed G. Caetano-Anollés (Hoboken, NJ: Wiley-Blackwell), 329-360.
    • (2010) Evolutionary Bioinformatics and Systems Biology , pp. 329-360
    • Sun, F.-J.1    Harish, A.2    Caetano-Anolles, G.3
  • 38
    • 84864298156 scopus 로고    scopus 로고
    • Nuclear RNase P of Trypanosoma brucei: a single protein in place of the multicomponent RNA-protein complex
    • doi: 10.1016/j.celrep.2012.05.021
    • Taschner, A., Weber, C., Buzet, A., Hartmann, R. K., Hartig, A., and Rossmanith, W. (2012). Nuclear RNase P of Trypanosoma brucei: a single protein in place of the multicomponent RNA-protein complex. Cell Rep. 2, 19-25. doi: 10.1016/j.celrep.2012.05.021
    • (2012) Cell Rep. , vol.2 , pp. 19-25
    • Taschner, A.1    Weber, C.2    Buzet, A.3    Hartmann, R.K.4    Hartig, A.5    Rossmanith, W.6
  • 39
    • 78650476811 scopus 로고    scopus 로고
    • A universal molecular clock of protein folds and its power in tracing the early history of aerobic metabolism and planet oxygenation
    • doi: 10.1093/molbev/msq232
    • Wang, M., Jiang, Y.-Y., Kim, K. M., Qu, G., Ji, H.-F., Mittenthal, J. E., et al. (2011). A universal molecular clock of protein folds and its power in tracing the early history of aerobic metabolism and planet oxygenation. Mol. Biol. Evol. 28, 567-582. doi: 10.1093/molbev/msq232
    • (2011) Mol. Biol. Evol. , vol.28 , pp. 567-582
    • Wang, M.1    Jiang, Y.-Y.2    Kim, K.M.3    Qu, G.4    Ji, H.-F.5    Mittenthal, J.E.6
  • 40
    • 0023449816 scopus 로고
    • tRNA-like structures tag the 3' ends of genomic RNA molecules for replication: implications for the origin of protein synthesis
    • doi: 10.1073/pnas.84.21.7383
    • Weiner, A. M., and Maizels, N. (1987). tRNA-like structures tag the 3' ends of genomic RNA molecules for replication: implications for the origin of protein synthesis. Proc. Natl. Acad. Sci. U.S.A. 84, 7383-7387. doi: 10.1073/pnas.84.21.7383
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 7383-7387
    • Weiner, A.M.1    Maizels, N.2
  • 41
    • 17844405021 scopus 로고    scopus 로고
    • Coevolution theory of the genetic code at age thirty
    • doi: 10.1002/bies.20208
    • Wong, J. T. (2005). Coevolution theory of the genetic code at age thirty. Bioessays 27, 416-425. doi: 10.1002/bies.20208
    • (2005) Bioessays , vol.27 , pp. 416-425
    • Wong, J.T.1
  • 42
    • 84855892823 scopus 로고    scopus 로고
    • Quality control in aminoacyl-tRNA synthesis: its role in translational fidelity
    • doi: 10.1016/B978-0-12-386497-0.00001-3
    • Yadavalli, S. S., and Ibba, M. (2012). Quality control in aminoacyl-tRNA synthesis: its role in translational fidelity. Adv. Protein Chem. Struct. Biol. 86, 1-43. doi: 10.1016/B978-0-12-386497-0.00001-3
    • (2012) Adv. Protein Chem. Struct. Biol. , vol.86 , pp. 1-43
    • Yadavalli, S.S.1    Ibba, M.2
  • 43
    • 34547607777 scopus 로고    scopus 로고
    • A first-principles model of early evolution: emergence of gene families, species and preferred protein folds
    • doi: 10.1371/journal.pcbi.0030139
    • Zeldovich, K. B., Chen, P., Shakhnovich, B. E., and Shakhnovich, E. I. (2007). A first-principles model of early evolution: emergence of gene families, species and preferred protein folds. PLoS Comput. Biol. 3:e139. doi: 10.1371/journal.pcbi.0030139
    • (2007) PLoS Comput. Biol. , vol.3
    • Zeldovich, K.B.1    Chen, P.2    Shakhnovich, B.E.3    Shakhnovich, E.I.4
  • 44
    • 0001895697 scopus 로고
    • Evolutionary divergence and convergence in proteins
    • eds V. Bryson and H. J. Vogel (New York, NY: Academic Press)
    • Zuckerkandl, E., and Pauling, L. (1965). "Evolutionary divergence and convergence in proteins," in Evolving Genes and Proteins, eds V. Bryson and H. J. Vogel (New York, NY: Academic Press), 97-166.
    • (1965) Evolving Genes and Proteins , pp. 97-166
    • Zuckerkandl, E.1    Pauling, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.