Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with Wiskott-Aldrich syndrome

Frontiers in Immunology

Volumn 5, Issue JUL, 2014, Pages

  O'Connell, Amy E ^a   Volpi, Stefano ^a   Dobbs, Kerry ^a   Fiorini, Claudia ^a   Tsitsikov, Erdyni ^a   de Boer, Helen ^a   Barlan, Isil B ^b   Despotovic, Jenny M ^c   Espinosa Rosales, Francisco J ^d   Hanson, I Celine ^c   Kanariou, Maria G ^e   Martínez Beckerat, Roxana ^f   Mayorga Sirera, Alvaro ^g   Mejia Carvajal, Carmen ^h   Radwan, Nesrine ⁱ   Weiss, Aaron R ^j   Pai, Sung Yun ^a   Lee, Yu Nee ^a   Notarangelo, Luigi D ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b MARMARA UNIVERSITY   (Turkey)

^c TEXAS CHILDREN S HOSPITAL   (United States)

^d INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^e AGHIA SOPHIA CHILDREN S HOSPITAL   (Greece)

^f Hospital Mario Catarino Rivas   (Honduras)

^g Centro de Neumologia y Alergia   (Honduras)

^h Manati Medical Center   (Puerto Rico)

ⁱ AIN SHAMS UNIVERSITY   (Egypt)

^j MAINE MEDICAL CENTER   (United States)

more..

Author keywords

B cell receptor; Clonotypic expansion; Deep sequencing; Immune repertoire; Next generation sequencing; Somatic hypermutation; T cell receptor; Wiskott Aldrich syndrome

Indexed keywords

EID: 84905637816     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00340     Document Type: Article

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