Bispecific antibody complex pre-targeting and targeted delivery of polymer drug conjugates for imaging and therapy in dual human mammary cancer xenografts: Targeted polymer drug conjugates for cancer diagnosis and therapy

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 41, Issue 8, 2014, Pages 1603-1616

  Khaw, Ban An ^a   Gada, Keyur S ^a   Patil, Vishwesh ^a   Panwar, Rajiv ^a   Mandapati, Savitri ^a   Hatefi, Arash ^b   Majewski, Stan ^c   Weisenberger, Andrew ^d  

^a NORTHEASTERN UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d THOMAS JEFFERSON NATIONAL ACCELERATOR FACILITY   (United States)

Author keywords

Affibody; Bispecific antibody; Doxorubicin; HER2 neu; Polymer drug conjugates

Indexed keywords

ANTIBODY CONJUGATE; BISPECIFIC ANTIBODY; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; PENTETIC ACID; PHOSPHATE BUFFERED SALINE; POLYGLUTAMIC ACID; POLYMER; RADIOISOTOPE; SUCCINYLPOLYLYSINE; TECHNETIUM 99M; UNCLASSIFIED DRUG; DRUG CARRIER; TECHNETIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BREAST CANCER; BREAST CARCINOMA; BREAST TUMOR; CANCER DIAGNOSIS; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG TARGETING; HUMAN; HUMAN CELL; MAXIMUM TOLERATED DOSE; MOUSE; NONHUMAN; RADIODIAGNOSIS; SCID MOUSE; XENOGRAFT; ANIMAL; CARCINOMA; CHEMISTRY; DIAGNOSTIC USE; DRUG SCREENING; FEMALE; IMMUNOLOGY; MAMMARY NEOPLASMS, EXPERIMENTAL; RADIOIMMUNOTHERAPY; SCINTISCANNING; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, BISPECIFIC; CARCINOMA; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, SCID; PENTETIC ACID; POLYGLUTAMIC ACID; RADIOIMMUNOTHERAPY; RECEPTOR, ERBB-2; TECHNETIUM; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84905566532     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-014-2738-2     Document Type: Article

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