Quantification of Doxorubicin and metabolites in rat plasma and small volume tissue samples by liquid chromatography/electrospray tandem mass spectroscopy

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 808, Issue 2, 2004, Pages 141-152

  Arnold, Robert D ^a   Slack, Jeanine E ^a   Straubinger, Robert M ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

7 deoxydoxorubicinolone; 7 deoxydoxorubicinone; 7 DXR olone; 7 DXR one; acetonitrile; ACN; CHOL; cholesterol; Daunorubicin; distearoylphosphatidylcholine; DNM; Doxorubicin; Doxorubicinol; doxorubicinolone; doxorubicinone; DSPC; DXR; DXR ol; DXR olone; DXR one; LC

Indexed keywords

CASCADE CONNECTIONS; DEMODULATION; DRUG DOSAGE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; TUMORS;

DOXORUBICIN; HUMAN MALIGNANCIES; RAT PLASMA;

METABOLITES;

7 DEOXYADRIAMYCINONE; 7 DEOXYDOXORUBICINOLONE; ADRIAMYCINONE; DOXORUBICIN; DOXORUBICIN DERIVATIVE; DOXORUBICINOL; DOXORUBICINOLONE; LIPOSOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; DRUG TISSUE LEVEL; ELECTROSPRAY MASS SPECTROMETRY; GLIOBLASTOMA; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOXORUBICIN; RATS; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TISSUE DISTRIBUTION;

EID: 3242664369     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2004.04.030     Document Type: Article

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