Telomere length in white blood cell DNA and lung cancer: A pooled analysis of three prospective cohorts

Cancer Research

Volumn 74, Issue 15, 2014, Pages 4090-4098

  Seow, Wei Jie ^a   Cawthon, Richard M ^b   Purdue, Mark P ^a   Hu, Wei ^a   Gao, Yu Tang ^g   Huang, Wen Yi ^a   Weinstein, Stephanie J ^a   Ji, Bu Tian ^a   Virtamo, Jarmo ⁱ   Hosgood III, H Dean ^c   Bassig, Bryan A ^a   Shu, Xiao Ou ^d   Cai, Qiuyin ^d   Xiang, Yong Bing ^h   Min, Shen ^a   Chow, Wong Ho ^e   Berndt, Sonja I ^a   Kim, Christopher ^a   Lim, Unhee ^f   Albanes, Demetrius ^a   Caporaso, Neil E ^a   Chanock, Stephen ^a   Zheng, Wei ^d   Rothman, Nathaniel ^a   Lan, Qing ^a   more..

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF TEXAS   (United States)

^f UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^g SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^h SHANGHAI CANCER INSTITUTE   (China)

ⁱ NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; TUMOR MARKER; DNA;

ADULT; AGED; ARTICLE; CANCER RISK; CLINICAL TRIAL (TOPIC); COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; HUMAN; LEUKOCYTE; LUNG ADENOCARCINOMA; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SMOKING; TELOMERE HOMEOSTASIS; BLOOD; CASE CONTROL STUDY; GENETICS; LUNG TUMOR; METABOLISM; MIDDLE AGED; PROSPECTIVE STUDY; RISK FACTOR; TELOMERE; ULTRASTRUCTURE;

CASE-CONTROL STUDIES; COHORT STUDIES; DNA; DNA, NEOPLASM; FEMALE; HUMANS; LEUKOCYTES; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; TELOMERE;

EID: 84905493151     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-0459     Document Type: Article

References (39)

1. Blasco MA. Telomeres and human disease: ageing, cancer and beyond. Nat Rev Genet 2005;6:611-22.
2. Jang JS, Choi YY, Lee WK, Choi JE, Cha SI, Kim YJ, et al. Telomere length and the risk of lung cancer. Cancer Sci 2008;99:1385-9.
3. Willeit P, Willeit J, Mayr A, Weger S, Oberhollenzer F, Brandstatter A, et al. Telomere length and risk of incident cancer and cancer mortality. JAMA 2010;304:69-75.
4. Ma HX, Zhou ZY, Wei S, Liu ZS, Pooley KA, Dunning AM, et al. Shortened telomere length is associated with increased risk of cancer: a meta-analysis. PLos ONE 2011;6.
5. Wentzensen IM, Mirabello L, Pfeiffer RM, Savage SA. The association of telomere length and cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev 2011;20:1238-50.
6. McGrath M, Wong JYY, Michaud D, Hunter DJ, De Vivo I. Telomere length, cigarette smoking, and bladder cancer risk in men and women. Cancer Epidemiol Biomarkers Prev 2007;16:815-9.
7. Pellatt AJ, Wolff RK, Torres-Mejia G, John EM, Herrick JS, Lundgreen A, et al. Telomere length, telomere-related genes, and breast cancer risk: the breast cancer health disparities study. Gene Chromosome Cancer 2013;52:595-609.
8. Qu SM, Wen WQ, Shu XO, Chow WH, Xiang YB, Wu J, et al. Association of leukocyte telomere length with breast cancer risk: nested case-control findings from the Shanghai Women's Health Study. Am J Epidemiol 2013;177:617-24.
9. Lan Q, Cawthon R, Shen M, Weinstein SJ, Virtamo J, Lim U, et al. A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of non-Hodgkin lymphoma. Clin Cancer Res 2009;15:7429-33.
10. Lynch SM, Major JM, Cawthon R, Weinstein SJ, Virtamo J, Lan Q, et al. A prospective analysis of telomere length and pancreatic cancer in the alpha-tocopherol beta-carotene cancer (ATBC) prevention study. Int J Cancer 2013;133:2672-80.
11. Gramatges MM, Telli ML, Balise R, Ford JM. Longer relative telomere length in blood from women with sporadic and familial breast cancer compared with healthy controls. Cancer Epidemiol Biomarkers Prev 2010;19:605-13.
12. Nan HM, Du MM, De Vivo I, Manson JE, Liu SM, McTiernan A, et al. Shorter telomeres associate with a reduced risk of melanoma development. Cancer Res 2011;71:6758-63.
13. Svenson U, Ljungberg B, Roos G. Telomere length in peripheral blood predicts survival in clear cell renal cell carcinoma. Cancer Res 2009;69:2896-901.
14. Weischer M, Nordestgaard BG, Cawthon RM, Freiberg JJ, Tybjrg-Hansen A, Bojesen SE. Short telomere length, cancer survival, and cancer risk in 47102 individuals. J Natl Cancer Inst 2013;105:459-68.
15. Lan Q, Cawthon R, Gao YT, Hu W, Hosgood HD, Barone-Adesi F, et al. Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China. PLos ONE 2013;8.
16. Shen M, Cawthon R, Rothman N, Weinstein SJ, Virtamo J, Hosgood HD 3rd, et al. A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of lung cancer. Lung Cancer 2011;73:133-7.
17. Purdue MP, Lan Q, Bagni R, Hocking W.G., Baris D, Reding DJ, et al. Prediagnostic serum levels of cytokines and other immune markers and risk of non-Hodgkin lymphoma. Cancer Res 2011;71:4898-907.
18. Prorok PC, Andriole GL, Bresalier RS, Buys SS, Chia D, Crawford ED, et al. Design of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Control Clin Trials 2000;21:273s-309s.
19. The ATBC Cancer Prevention Study Group. The alpha-tocopherol, beta-carotene lung cancer prevention study: design, methods, participant characteristics, and compliance. Ann Epidemiol 1994;4:1-10.
20. Zheng W, Chow WH, Yang G, Jin F, Rothman N, Blair A, et al. The Shanghai Women's Health Study: rationale, study design, and baseline characteristics. Am J Epidemiol 2005;162:1123-31.
21. Cawthon RM. Telomere length measurement by a novel monochrome multiplex quantitative PCR method. Nucleic Acids Res 2009;37.
22. Wu XF, Amos CI, Zhu Y, Zhao H, Grossman BH, Shay JW, et al. Telomere dysfunction: a potential cancer predisposition factor. J Natl Cancer Inst 2003;95:1211-8.
23. Hosgood HD, Cawthon R, He XZ, Chanock S, Lan Q. Genetic variation in telomere maintenance genes, telomere length, and lung cancer susceptibility. Lung Cancer 2009;66:157-61.
24. Savage SA, Gadalla SM, Chanock SJ. The long and short of telomeres and cancer association studies. J Natl Cancer Inst 2013;105:448-9.
25. Hackett JA, Greider CW. Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis. Oncogene 2002;21:619-26.
26. Bryan TM, Englezou A, Gupta J, Bacchetti S, Reddel RR. Telomere elongation in immortal human-cells without detectable telomerase activity. EMBO J 1995;14:4240-8.
27. Mooi WJ, Peeper DS. Oncogene-induced cell senescence - Halting on the road to cancer. N Engl J Med 2006;355:1037-46.
28. Bull CF, Mayrhofer G, O'Callaghan NJ, Au AY, Pickett HA, Low GKM, et al. Folate deficiency induces dysfunctional long and short telomeres; both states are associated with hypomethylation and DNA damage in human WIL2-NS cells. Cancer Prev Res 2014;7:128-38.
29. Gadalla SM, Cawthon R, Giri N, Alter BP, Savage SA. Telomere length in blood, buccal cells, and fibroblasts from patients with inherited bone marrow failure syndromes. Aging-Us 2010;2:867-74.
30. Hou LF, Zhang X, Gawron AJ, Liu J. Surrogate tissue telomere length and cancer risk: shorter or longer? Cancer Lett 2012;319:130-5.
31. Reddel RR. The role of senescence and immortalization in carcinogenesis. Carcinogenesis 2000;21:477-84.
32. Anic GM, Sondak VK, Messina JL, Fenske NA, Zager JS, Cherpelis BS, et al. Telomere length and risk of melanoma, squamous cell carcinoma, and basal cell carcinoma. Cancer Epidemiol 2013;37:434-9.
33. McDoniels-Silvers AL, Nimri CF, Stoner GD, Lubet RA, You M. Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas. Clin Cancer Res 2002;8:1127-38.
34. Pezzella F, Turley H, Kuzu I, Tungekar MF, Dunnill MS, Pierce CB, et al. Bcl-2 protein in non-small-cell lung-carcinoma. N Engl J Med 1993;329:690-4.
35. Subramanian J, Govindan R. Lung cancer in never smokers: a review. J Clin Oncol 2007;25:561-70.
36. Radzikowska E, Glaz P, Roszkowski K. Lung cancer in women: age, smoking, histology, performance status, stage, initial treatment and survival. Population-based study of 20 561 cases. Ann Oncol 2002;13:1087-93.
37. Hsiung CA, Lan Q, Hong YC, Chen CJ, Hosgood HD, Chang IS, et al. The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLos Genet 2010;6.
38. Landi MT, Chatterjee N, Yu K, Goldin LR, Goldstein AM, Rotunno M, et al. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet 2009;85:679-91.
39. Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL, et al. Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet 2013;45:422-7.