Folate deficiency induces dysfunctional long and short telomeres; Both states are associated with hypomethylation and DNA damage in human WIL2-NS cells

Cancer Prevention Research

Volumn 7, Issue 1, 2014, Pages 128-138

  Bull, Caroline F ^a,b   Mayrhofer, Graham ^b   O'Callaghan, Nathan J ^a   Au, Amy Y ^c   Pickett, Hilda A ^c,d   Low, Grace Kah Mun ^e   Zeegers, Dimphy ^e   Hande, M Prakash ^e,f   Fenech, Michael F ^a  

^a CSIRO   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

^e NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DNA; FOLIC ACID; TELOMERASE REVERSE TRANSCRIPTASE; URACIL;

ARTICLE; CHROMOSOMAL INSTABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINESIS; DNA DAMAGE; DNA METHYLATION; FLUORESCENCE IN SITU HYBRIDIZATION; FOLIC ACID DEFICIENCY; GENETIC MARKER; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MICRONUCLEUS TEST; MITOSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING;

AZACITIDINE; BIOLOGICAL MARKERS; CHROMOSOMAL INSTABILITY; CYTOKINESIS; DIET; DNA DAMAGE; DNA METHYLATION; FOLIC ACID; FOLIC ACID DEFICIENCY; HUMANS; TELOMERASE; TELOMERE; URACIL;

EID: 84892419961     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-13-0264     Document Type: Article

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