-
1
-
-
77955358457
-
Lung organogenesis
-
Warburton D, El-Hashash A, Carraro G, Tiozzo C, Sala F, Rogers O, De Langhe S, Kemp PJ, Riccardi D, Torday J, et al. Lung organogenesis. Curr Top Dev Biol 2010;90:73-158.
-
(2010)
Curr Top Dev Biol
, vol.90
, pp. 73-158
-
-
Warburton, D.1
El-Hashash, A.2
Carraro, G.3
Tiozzo, C.4
Sala, F.5
Rogers, O.6
De Langhe, S.7
Kemp, P.J.8
Riccardi, D.9
Torday, J.10
-
2
-
-
74049139927
-
Preparing for the first breath: Genetic and cellular mechanisms in lung development
-
Morrisey EE, Hogan BL. Preparing for the first breath: genetic and cellular mechanisms in lung development. Dev Cell 2010;18:8-23.
-
(2010)
Dev Cell
, vol.18
, pp. 8-23
-
-
Morrisey, E.E.1
Hogan, B.L.2
-
3
-
-
20444498904
-
Fetal lung and diaphragm development in congenital diaphragmatic hernia
-
Rottier R, Tibboel D. Fetal lung and diaphragm development in congenital diaphragmatic hernia. Semin Perinatol 2005;29:86-93.
-
(2005)
Semin Perinatol
, vol.29
, pp. 86-93
-
-
Rottier, R.1
Tibboel, D.2
-
4
-
-
0017740851
-
Congenital cystic adenomatoid malformation of the lung: Classification and morphologic spectrum
-
Stocker JT, Madewell JE, Drake RM. Congenital cystic adenomatoid malformation of the lung: classification and morphologic spectrum. Hum Pathol 1977;8:155-171.
-
(1977)
Hum Pathol
, vol.8
, pp. 155-171
-
-
Stocker, J.T.1
Madewell, J.E.2
Drake, R.M.3
-
5
-
-
42649142250
-
Sox2 is important for two crucial processes in lung development: Branching morphogenesis and epithelial cell differentiation
-
Gontan C, de Munck A, Vermeij M, Grosveld F, Tibboel D, Rottier R. Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation. Dev Biol 2008;317:296-309.
-
(2008)
Dev Biol
, vol.317
, pp. 296-309
-
-
Gontan, C.1
De Munck, A.2
Vermeij, M.3
Grosveld, F.4
Tibboel, D.5
Rottier, R.6
-
6
-
-
79960566484
-
Sox2 activates cell proliferation and differentiation in the respiratory epithelium
-
Tompkins DH, Besnard V, Lange AW, Keiser AR, Wert SE, Bruno MD, Whitsett JA. Sox2 activates cell proliferation and differentiation in the respiratory epithelium. Am J Respir Cell Mol Biol 2011;45:101-110.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 101-110
-
-
Tompkins, D.H.1
Besnard, V.2
Lange, A.W.3
Keiser, A.R.4
Wert, S.E.5
Bruno, M.D.6
Whitsett, J.A.7
-
7
-
-
69549090537
-
Multiple roles for sox2 in the developing and adult mouse trachea
-
Que J, Luo X, Schwartz RJ, Hogan BL. Multiple roles for sox2 in the developing and adult mouse trachea. Development 2009;136:1899-1907.
-
(2009)
Development
, vol.136
, pp. 1899-1907
-
-
Que, J.1
Luo, X.2
Schwartz, R.J.3
Hogan, B.L.4
-
8
-
-
0037227099
-
Multipotent cell lineages in early mouse development depend on sox2 function
-
Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R. Multipotent cell lineages in early mouse development depend on sox2 function. Genes Dev 2003;17:126-140.
-
(2003)
Genes Dev
, vol.17
, pp. 126-140
-
-
Avilion, A.A.1
Nicolis, S.K.2
Pevny, L.H.3
Perez, L.4
Vivian, N.5
Lovell-Badge, R.6
-
9
-
-
84872046078
-
The sox family of transcription factors: Versatile regulators of stem and progenitor cell fate
-
Sarkar A, Hochedlinger K. The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. Cell StemCell 2013;12:15-30.
-
(2013)
Cell StemCell
, vol.12
, pp. 15-30
-
-
Sarkar, A.1
Hochedlinger, K.2
-
10
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
11
-
-
34447530782
-
Multiple dose-dependent roles for sox2 in the patterning and differentiation of anterior foregut endoderm
-
Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan BL. Multiple dose-dependent roles for sox2 in the patterning and differentiation of anterior foregut endoderm. Development 2007;134:2521-2531.
-
(2007)
Development
, vol.134
, pp. 2521-2531
-
-
Que, J.1
Okubo, T.2
Goldenring, J.R.3
Nam, K.T.4
Kurotani, R.5
Morrisey, E.E.6
Taranova, O.7
Pevny, L.H.8
Hogan, B.L.9
-
12
-
-
77956224492
-
Evidence that sox2 overexpression is oncogenic in the lung
-
Lu Y, Futtner C, Rock JR, Xu X, Whitworth W, Hogan BL, Onaitis MW. Evidence that sox2 overexpression is oncogenic in the lung. PLoS ONE 2010;5:e11022.
-
(2010)
PLoS ONE
, vol.5
-
-
Lu, Y.1
Futtner, C.2
Rock, J.R.3
Xu, X.4
Whitworth, W.5
Hogan, B.L.6
Onaitis, M.W.7
-
14
-
-
69149106207
-
Basal cells as stem cells of the mouse trachea and human airway epithelium
-
Rock JR, Onaitis MW, Rawlins EL, Lu Y, Clark CP, Xue Y, Randell SH, Hogan BL. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci USA 2009;106:12771-12775.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12771-12775
-
-
Rock, J.R.1
Onaitis, M.W.2
Rawlins, E.L.3
Lu, Y.4
Clark, C.P.5
Xue, Y.6
Randell, S.H.7
Hogan, B.L.8
-
15
-
-
2942677539
-
Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium
-
Daniely Y, Liao G, Dixon D, Linnoila RI, Lori A, Randell SH, Oren M, Jetten AM. Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am J Physiol Cell Physiol 2004;287:C171-C181.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
-
-
Daniely, Y.1
Liao, G.2
Dixon, D.3
Linnoila, R.I.4
Lori, A.5
Randell, S.H.6
Oren, M.7
Jetten, A.M.8
-
16
-
-
0037308609
-
P63 is expressed in basal and myoepithelial cells of human normal and tumor salivary gland tissues
-
Bilal H, Handra-Luca A, Bertrand JC, Fouret PJ. P63 is expressed in basal and myoepithelial cells of human normal and tumor salivary gland tissues. J Histochem Cytochem 2003;51:133-139.
-
(2003)
J Histochem Cytochem
, vol.51
, pp. 133-139
-
-
Bilal, H.1
Handra-Luca, A.2
Bertrand, J.C.3
Fouret, P.J.4
-
17
-
-
0033594485
-
P63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
-
Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, Bronson RT, Tabin C, Sharpe A, Caput D, Crum C, et al. P63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 1999;398:714-718.
-
(1999)
Nature
, vol.398
, pp. 714-718
-
-
Yang, A.1
Schweitzer, R.2
Sun, D.3
Kaghad, M.4
Walker, N.5
Bronson, R.T.6
Tabin, C.7
Sharpe, A.8
Caput, D.9
Crum, C.10
-
18
-
-
0033594491
-
P63 is a p53 homologue required for limb and epidermal morphogenesis
-
Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. P63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999;398:708-713.
-
(1999)
Nature
, vol.398
, pp. 708-713
-
-
Mills, A.A.1
Zheng, B.2
Wang, X.J.3
Vogel, H.4
Roop, D.R.5
Bradley, A.6
-
19
-
-
84856188471
-
Deltanp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation
-
Romano RA, Smalley K, Magraw C, Serna VA, Kurita T, Raghavan S, Sinha S. Deltanp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation. Development 2012;139:772-782.
-
(2012)
Development
, vol.139
, pp. 772-782
-
-
Romano, R.A.1
Smalley, K.2
Magraw, C.3
Serna, V.A.4
Kurita, T.5
Raghavan, S.6
Sinha, S.7
-
20
-
-
34250188106
-
Novel in vivo targets of deltanp63 in keratinocytes identified by a modified chromatin immunoprecipitation approach
-
Birkaya B, Ortt K, Sinha S. Novel in vivo targets of deltanp63 in keratinocytes identified by a modified chromatin immunoprecipitation approach. BMC Mol Biol 2007;8:43.
-
(2007)
BMC Mol Biol
, vol.8
, pp. 43
-
-
Birkaya, B.1
Ortt, K.2
Sinha, S.3
-
21
-
-
33646365381
-
The unique nh2-terminally deleted (deltan) residues, the pxxp motif, and the ppxy motif are required for the transcriptional activity of the deltan variant of p63
-
Helton ES, Zhu J, Chen X. The unique nh2-terminally deleted (deltan) residues, the pxxp motif, and the ppxy motif are required for the transcriptional activity of the deltan variant of p63. J Biol Chem 2006;281:2533-2542.
-
(2006)
J Biol Chem
, vol.281
, pp. 2533-2542
-
-
Helton, E.S.1
Zhu, J.2
Chen, X.3
-
22
-
-
46949086501
-
A chromatin immunoprecipitation screen in mouse keratinocytes reveals runx1 as a direct transcriptional target of deltanp63
-
Ortt K, Raveh E, Gat U, Sinha S. A chromatin immunoprecipitation screen in mouse keratinocytes reveals runx1 as a direct transcriptional target of deltanp63. J Cell Biochem 2008;104:1204-1219.
-
(2008)
J Cell Biochem
, vol.104
, pp. 1204-1219
-
-
Ortt, K.1
Raveh, E.2
Gat, U.3
Sinha, S.4
-
23
-
-
66049096917
-
An active role of the deltan isoform of p63 in regulating basal keratin genes k5 and k14 and directing epidermal cell fate
-
Romano RA, Ortt K, Birkaya B, Smalley K, Sinha S. An active role of the deltan isoform of p63 in regulating basal keratin genes k5 and k14 and directing epidermal cell fate. PLoS ONE 2009;4:e5623.
-
(2009)
PLoS ONE
, vol.4
-
-
Romano, R.A.1
Ortt, K.2
Birkaya, B.3
Smalley, K.4
Sinha, S.5
-
24
-
-
84871778678
-
Sox2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype
-
Raghoebir L, Bakker ER, Mills JC, Swagemakers S, Buscop-van Kempen M, Boerema-de Munck A, Driegen S, Meijer D, Grosveld F, Tibboel D, et al. Sox2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype. J Mol Cell Biol 2012;4:377-385.
-
(2012)
J Mol Cell Biol
, vol.4
, pp. 377-385
-
-
Raghoebir, L.1
Bakker, E.R.2
Mills, J.C.3
Swagemakers, S.4
Buscop-Van Kempen, M.5
Boerema-De Munck, A.6
Driegen, S.7
Meijer, D.8
Grosveld, F.9
Tibboel, D.10
-
25
-
-
0036008331
-
Conditional gene expression in the respiratory epithelium of the mouse
-
Perl AK, Tichelaar JW, Whitsett JA. Conditional gene expression in the respiratory epithelium of the mouse. Transgenic Res 2002;11:21-29.
-
(2002)
Transgenic Res
, vol.11
, pp. 21-29
-
-
Perl, A.K.1
Tichelaar, J.W.2
Whitsett, J.A.3
-
26
-
-
78649816004
-
Induction of deltanp63 by the newly identified keratinocyte-specific transforming growth factor beta signaling pathway with smad2 and ikappab kinase alpha in squamous cell carcinoma
-
Fukunishi N, Katoh I, Tomimori Y, Tsukinoki K, Hata R, Nakao A, Ikawa Y, Kurata S. Induction of deltanp63 by the newly identified keratinocyte-specific transforming growth factor beta signaling pathway with smad2 and ikappab kinase alpha in squamous cell carcinoma. Neoplasia 2010;12:969-979.
-
(2010)
Neoplasia
, vol.12
, pp. 969-979
-
-
Fukunishi, N.1
Katoh, I.2
Tomimori, Y.3
Tsukinoki, K.4
Hata, R.5
Nakao, A.6
Ikawa, Y.7
Kurata, S.8
-
27
-
-
84864565572
-
Deltanp63alpha mediates proliferation and apoptosis in human gastric cancer cells by the regulation of gata-6
-
Wang H, Liu Z, Li J, Zhao X, Wang Z, Xu H. Deltanp63alpha mediates proliferation and apoptosis in human gastric cancer cells by the regulation of gata-6. Neoplasma 2012;59:416-423.
-
(2012)
Neoplasma
, vol.59
, pp. 416-423
-
-
Wang, H.1
Liu, Z.2
Li, J.3
Zhao, X.4
Wang, Z.5
Xu, H.6
-
28
-
-
0034961448
-
Branching and differentiation defects in pulmonary epithelium with elevated gata6 expression
-
Koutsourakis M, Keijzer R, Visser P, Post M, Tibboel D, Grosveld F. Branching and differentiation defects in pulmonary epithelium with elevated gata6 expression. Mech Dev 2001;105:105-114.
-
(2001)
Mech Dev
, vol.105
, pp. 105-114
-
-
Koutsourakis, M.1
Keijzer, R.2
Visser, P.3
Post, M.4
Tibboel, D.5
Grosveld, F.6
-
29
-
-
0036337973
-
Gata6 regulates differentiation of distal lung epithelium
-
Yang H, Lu MM, Zhang L, Whitsett JA, Morrisey EE. Gata6 regulates differentiation of distal lung epithelium. Development 2002;129:2233-2246.
-
(2002)
Development
, vol.129
, pp. 2233-2246
-
-
Yang, H.1
Lu, M.M.2
Zhang, L.3
Whitsett, J.A.4
Morrisey, E.E.5
-
32
-
-
34347364738
-
Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development
-
Ramasamy SK, Mailleux AA, Gupte VV, Mata F, Sala FG, Veltmaat JM, Del Moral PM, De Langhe S, Parsa S, Kelly LK, et al. Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development. Dev Biol 2007;307:237-247.
-
(2007)
Dev Biol
, vol.307
, pp. 237-247
-
-
Ramasamy, S.K.1
Mailleux, A.A.2
Gupte, V.V.3
Mata, F.4
Sala, F.G.5
Veltmaat, J.M.6
Del Moral, P.M.7
De Langhe, S.8
Parsa, S.9
Kelly, L.K.10
-
33
-
-
40349083964
-
Fgf10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia
-
Nyeng P, Norgaard GA, Kobberup S, Jensen J. Fgf10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia. BMC Dev Biol 2008;8:2.
-
(2008)
BMC Dev Biol
, vol.8
, pp. 2
-
-
Nyeng, P.1
Norgaard, G.A.2
Kobberup, S.3
Jensen, J.4
-
34
-
-
84862107772
-
Beta-catenin-sox2 signaling regulates the fate of developing airway epithelium
-
Hashimoto S, Chen H, Que J, Brockway BL, Drake JA, Snyder JC, Randell SH, Stripp BR. Beta-catenin-sox2 signaling regulates the fate of developing airway epithelium. J Cell Sci 2012;125:932-942.
-
(2012)
J Cell Sci
, vol.125
, pp. 932-942
-
-
Hashimoto, S.1
Chen, H.2
Que, J.3
Brockway, B.L.4
Drake, J.A.5
Snyder, J.C.6
Randell, S.H.7
Stripp, B.R.8
-
35
-
-
61349155553
-
Mesodermal deletion of transforming growth factor-beta receptor ii disrupts lung epithelial morphogenesis: Cross-talk between tgf-beta and sonic hedgehog pathways
-
Li M, Li C, Liu YH, Xing Y, Hu L, Borok Z, Kwong KY, Minoo P. Mesodermal deletion of transforming growth factor-beta receptor ii disrupts lung epithelial morphogenesis: cross-talk between tgf-beta and sonic hedgehog pathways. J Biol Chem 2008;283:36257-36264.
-
(2008)
J Biol Chem
, vol.283
, pp. 36257-36264
-
-
Li, M.1
Li, C.2
Liu, Y.H.3
Xing, Y.4
Hu, L.5
Borok, Z.6
Kwong, K.Y.7
Minoo, P.8
-
36
-
-
20444445954
-
Wnt/beta-catenin signaling acts upstream of n-myc, bmp4, and fgf signaling to regulate proximaldistal patterning in the lung
-
Shu W, Guttentag S, Wang Z, Andl T, Ballard P, Lu MM, Piccolo S, Birchmeier W, Whitsett JA, Millar SE, et al. Wnt/beta-catenin signaling acts upstream of n-myc, bmp4, and fgf signaling to regulate proximaldistal patterning in the lung. Dev Biol 2005;283:226-239.
-
(2005)
Dev Biol
, vol.283
, pp. 226-239
-
-
Shu, W.1
Guttentag, S.2
Wang, Z.3
Andl, T.4
Ballard, P.5
Lu, M.M.6
Piccolo, S.7
Birchmeier, W.8
Whitsett, J.A.9
Millar, S.E.10
-
37
-
-
79951542163
-
Signaling through bmp receptors promotes respiratory identity in the foregut via repression of sox2
-
Domyan ET, Ferretti E, Throckmorton K, Mishina Y, Nicolis SK, Sun X. Signaling through bmp receptors promotes respiratory identity in the foregut via repression of sox2. Development 2011;138:971-981.
-
(2011)
Development
, vol.138
, pp. 971-981
-
-
Domyan, E.T.1
Ferretti, E.2
Throckmorton, K.3
Mishina, Y.4
Nicolis, S.K.5
Sun, X.6
-
38
-
-
33644764648
-
Evidence that autocrine signaling through bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells
-
Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL. Evidence that autocrine signaling through bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol 2006;291:67-82.
-
(2006)
Dev Biol
, vol.291
, pp. 67-82
-
-
Eblaghie, M.C.1
Reedy, M.2
Oliver, T.3
Mishina, Y.4
Hogan, B.L.5
-
39
-
-
84905479433
-
Lung epithelial branching program antagonizes alveolar differentiation
-
In press
-
Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J. Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci USA (In press)
-
Proc Natl Acad Sci USA
-
-
Chang, D.R.1
Martinez Alanis, D.2
Miller, R.K.3
Ji, H.4
Akiyama, H.5
McCrea, P.D.6
Chen, J.7
-
40
-
-
84883237460
-
Localized fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors
-
Volckaert T, Campbell A, Dill E, Li C, Minoo P, De Langhe S. Localized fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors. Development 2013;140:3731-3742.
-
(2013)
Development
, vol.140
, pp. 3731-3742
-
-
Volckaert, T.1
Campbell, A.2
Dill, E.3
Li, C.4
Minoo, P.5
De Langhe, S.6
-
41
-
-
84880875969
-
Fgfr2 signaling underlies p63 oncogenic function in squamous cell carcinoma
-
Ramsey MR, Wilson C, Ory B, Rothenberg SM, Faquin W, Mills AA, Ellisen LW. Fgfr2 signaling underlies p63 oncogenic function in squamous cell carcinoma. J Clin Invest 2013;123:3525-3538.
-
(2013)
J Clin Invest
, vol.123
, pp. 3525-3538
-
-
Ramsey, M.R.1
Wilson, C.2
Ory, B.3
Rothenberg, S.M.4
Faquin, W.5
Mills, A.A.6
Ellisen, L.W.7
-
42
-
-
46249127489
-
A gata6-wnt pathway required for epithelial stem cell development and airway regeneration
-
Zhang Y, Goss AM, Cohen ED, Kadzik R, Lepore JJ, Muthukumaraswamy K, Yang J, DeMayo FJ, Whitsett JA, Parmacek MS, et al. A gata6-wnt pathway required for epithelial stem cell development and airway regeneration. Nat Genet 2008;40:862-870.
-
(2008)
Nat Genet
, vol.40
, pp. 862-870
-
-
Zhang, Y.1
Goss, A.M.2
Cohen, E.D.3
Kadzik, R.4
Lepore, J.J.5
Muthukumaraswamy, K.6
Yang, J.7
DeMayo, F.J.8
Whitsett, J.A.9
Parmacek, M.S.10
-
43
-
-
0032590183
-
The transcription factor gata6 is essential for early extraembryonic development
-
Koutsourakis M, Langeveld A, Patient R, Beddington R, Grosveld F. The transcription factor gata6 is essential for early extraembryonic development. Development 1999;126:723-732.
-
(1999)
Development
, vol.126
, pp. 723-732
-
-
Koutsourakis, M.1
Langeveld, A.2
Patient, R.3
Beddington, R.4
Grosveld, F.5
-
44
-
-
79960470568
-
Gata6 activates wnt signaling in pancreatic cancer by negatively regulating the wnt antagonist dickkopf-1
-
Zhong Y, Wang Z, Fu B, Pan F, Yachida S, Dhara M, Albesiano E, Li L, Naito Y, Vilardell F, et al. Gata6 activates wnt signaling in pancreatic cancer by negatively regulating the wnt antagonist dickkopf-1. PLoS ONE 2011;6:e22129.
-
(2011)
PLoS ONE
, vol.6
-
-
Zhong, Y.1
Wang, Z.2
Fu, B.3
Pan, F.4
Yachida, S.5
Dhara, M.6
Albesiano, E.7
Li, L.8
Naito, Y.9
Vilardell, F.10
-
45
-
-
70450196056
-
The id21 distal tip lung epithelium contains individual multipotent embryonic progenitor cells
-
Rawlins EL, Clark CP, Xue Y, Hogan BL. The id21 distal tip lung epithelium contains individual multipotent embryonic progenitor cells. Development 2009;136:3741-3745.
-
(2009)
Development
, vol.136
, pp. 3741-3745
-
-
Rawlins, E.L.1
Clark, C.P.2
Xue, Y.3
Hogan, B.L.4
|